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Department of Biomedical Sciences
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Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability.
Cancer research May, 2002 | Pubmed ID: 11980640
Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice.
Cancer research Sep, 2002 | Pubmed ID: 12234974
Minimal effects of dietary restriction on neuroendocrine carcinogenesis in Rb+/- mice.
Carcinogenesis Feb, 2003 | Pubmed ID: 12584165
Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.
Cancer research Jul, 2003 | Pubmed ID: 12839925
Mammary carcinoma suppression by cellular retinoic acid binding protein-II.
Cancer research Aug, 2003 | Pubmed ID: 12907615
Use of multiphoton imaging for studying cell migration in the mouse.
Methods in molecular biology (Clifton, N.J.) , 2005 | Pubmed ID: 15576922
Suppression of melanotroph carcinogenesis leads to accelerated progression of pituitary anterior lobe tumors and medullary thyroid carcinomas in Rb+/- mice.
Cancer research Feb, 2005 | Pubmed ID: 15705875
Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer.
Cancer research Aug, 2006 | Pubmed ID: 16912162
Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts.
Cancer research Jun, 2007 | Pubmed ID: 17553900
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth.
Cancer research Sep, 2007 | Pubmed ID: 17823410
Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia.
Carcinogenesis Mar, 2008 | Pubmed ID: 17893233
Toxicity and biomedical imaging of layered nanohybrids in the mouse.
Toxicologic pathology Oct, 2007 | Pubmed ID: 17943654
Core-shell silica nanoparticles as fluorescent labels for nanomedicine.
Journal of biomedical optics Nov-Dec, 2007 | Pubmed ID: 18163823
Role of p53 and Rb in ovarian cancer.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 18546622
Mouse models for cancer stem cell research.
Toxicologic pathology Jan, 2010 | Pubmed ID: 19920280
Frequent downregulation of miR-34 family in human ovarian cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research Feb, 2010 | Pubmed ID: 20145172
Strategies for high-resolution imaging of epithelial ovarian cancer by laparoscopic nonlinear microscopy.
Translational oncology , 2010 | Pubmed ID: 20563260
Conditional knockout of fibronectin abrogates mouse mammary gland lobuloalveolar differentiation.
Developmental biology Oct, 2010 | Pubmed ID: 20624380
Mouse prostate cancer cell lines established from primary and postcastration recurrent tumors.
Hormones & cancer Feb, 2010 | Pubmed ID: 20631921
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology Nov, 2010 | Pubmed ID: 20864684
Wild-type p53 controls cell motility and invasion by dual regulation of MET expression.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21831840
MET-dependent cancer invasion may be preprogrammed by early alterations of p53-regulated feedforward loop and triggered by stromal cell-derived HGF.
Cell cycle (Georgetown, Tex.) Nov, 2011 | Pubmed ID: 22071625
Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.
Nature Mar, 2013 | Pubmed ID: 23467088
miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment.
Cell reports Mar, 2014 | Pubmed ID: 24630988
Role of the stem cell niche in the pathogenesis of epithelial ovarian cancers.
Molecular & cellular oncology Jul-Sep, 2014 | Pubmed ID: 27308341
Cornell University
Andrea Flesken-Nikitin1,
Blaine A. Harlan1,
Alexander Yu. Nikitin1
1Department of Biomedical Sciences, Cornell University
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