Nabeel R. Yaseen

Biphenotypic acute leukemia with coexpression of CD79a and markers of myeloid lineage.

The oncogene Nup98-HOXA9 induces gene transcription in myeloid cells.

CD45-associated protein inhibits CD45 dimerization and up-regulates its protein tyrosine phosphatase activity.

Purification of RanGDP, RanGTP, and RanGMPPNP by ion exchange chromatography.

Carrier-independent nuclear import of the transcription factor PU.1 via RanGTP-stimulated binding to Nup153.

NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells.

Ultrastructural nuclear import assay.

Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9.

Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins.

In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML.

Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming ability.