Mark D. Zabel

Depletion of Lyn kinase from the BCR complex and inhibition of B cell activation by excess CD21 ligation.

Yin Yang 1, Oct1, and NFAT-4 form repeating, cyclosporin-sensitive regulatory modules within the murine CD21 intronic control region.

Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses.

Efficient in vitro amplification of chronic wasting disease PrPRES.

Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.

In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification.

Trans-species amplification of PrP(CWD) and correlation with rigid loop 170N.

Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay.

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system.

Detection of protease-resistant cervid prion protein in water from a CWD-endemic area.

Detection of sub-clinical CWD infection in conventional test-negative deer long after oral exposure to urine and feces from CWD+ deer.

Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures.

Sensitivity of protein misfolding cyclic amplification versus immunohistochemistry in ante-mortem detection of chronic wasting disease.

Detection of PrPCWD in feces from naturally exposed Rocky Mountain elk (Cervus elaphus nelsoni) using protein misfolding cyclic amplification.

Detection of prion protein in the cerebrospinal fluid of elk (Cervus canadensis nelsoni) with chronic wasting disease using protein misfolding cyclic amplification.

Incunabular immunological events in prion trafficking.

Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease.

Lipopeptide delivery of siRNA to the central nervous system.

Estimating prion adsorption capacity of soil by BioAssay of Subtracted Infectivity from Complex Solutions (BASICS).

Intranasal inoculation of white-tailed deer (Odocoileus virginianus) with lyophilized chronic wasting disease prion particulate complexed to montmorillonite clay.

Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease.

Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons.

Prions--not your immunologist's pathogen.

A brief history of prions.

Detection and Quantification of CWD Prions in Fixed Paraffin Embedded Tissues by Real-Time Quaking-Induced Conversion.

Dietary magnesium and copper affect survival time and neuroinflammation in chronic wasting disease.

Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice.

Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification.

Endogenous Brain Lipids Inhibit Prion Amyloid Formation .

Pathways of Prion Spread during Early Chronic Wasting Disease in Deer.

Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis.

Relative Impact of Complement Receptors CD21/35 (Cr2/1) on Scrapie Pathogenesis in Mice.

Lipopeptide Delivery of siRNA to the Central Nervous System.

Chronic Wasting Disease in Cervids: Implications for Prion Transmission to Humans and Other Animal Species.

siRNA Therapeutics for Protein Misfolding Diseases of the Central Nervous System.

Tissue-specific biochemical differences between chronic wasting disease prions isolated from free-ranging white-tailed deer (Odocoileus virginianus).

Adipose-derived mesenchymal stromal cells decrease prion-induced glial inflammation in vitro.

A multiplexed, paired-pooled droplet digital PCR assay for detection of SARS-CoV-2 in saliva.

Intranasally delivered mesenchymal stromal cells decrease glial inflammation early in prion disease.