Department of Microbiology,
Immunology and Pathology,
Immunology,
and Pathology,
College of Veterinary Medicine and Biomedical Sciences,
Department of Microbiology, Immunology and Pathology,
Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences,
Prion Research Center,
Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences
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Depletion of Lyn kinase from the BCR complex and inhibition of B cell activation by excess CD21 ligation.
International immunology Feb, 2002 | Pubmed ID: 11809733
Yin Yang 1, Oct1, and NFAT-4 form repeating, cyclosporin-sensitive regulatory modules within the murine CD21 intronic control region.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2002 | Pubmed ID: 11907091
Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses.
Immunity Dec, 2002 | Pubmed ID: 12479818
Efficient in vitro amplification of chronic wasting disease PrPRES.
Journal of virology Sep, 2007 | Pubmed ID: 17553879
Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2007 | Pubmed ID: 17947689
In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification.
Virology Dec, 2008 | Pubmed ID: 18952250
Trans-species amplification of PrP(CWD) and correlation with rigid loop 170N.
Virology Apr, 2009 | Pubmed ID: 19269662
Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay.
PloS one , 2009 | Pubmed ID: 19293928
CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system.
Brain : a journal of neurology Sep, 2009 | Pubmed ID: 19531531
Detection of protease-resistant cervid prion protein in water from a CWD-endemic area.
Prion Jul-Sep, 2009 | Pubmed ID: 19823039
Detection of sub-clinical CWD infection in conventional test-negative deer long after oral exposure to urine and feces from CWD+ deer.
PloS one , 2009 | Pubmed ID: 19956732
Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures.
PloS one , 2010 | Pubmed ID: 20559428
Sensitivity of protein misfolding cyclic amplification versus immunohistochemistry in ante-mortem detection of chronic wasting disease.
The Journal of general virology May, 2012 | Pubmed ID: 22278825
Detection of PrPCWD in feces from naturally exposed Rocky Mountain elk (Cervus elaphus nelsoni) using protein misfolding cyclic amplification.
Journal of wildlife diseases Apr, 2012 | Pubmed ID: 22493117
Detection of prion protein in the cerebrospinal fluid of elk (Cervus canadensis nelsoni) with chronic wasting disease using protein misfolding cyclic amplification.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc Jul, 2012 | Pubmed ID: 22621952
Incunabular immunological events in prion trafficking.
Scientific reports , 2012 | Pubmed ID: 22679554
Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2012 | Pubmed ID: 23002439
Lipopeptide delivery of siRNA to the central nervous system.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23070775
Estimating prion adsorption capacity of soil by BioAssay of Subtracted Infectivity from Complex Solutions (BASICS).
PloS one , 2013 | Pubmed ID: 23484043
Intranasal inoculation of white-tailed deer (Odocoileus virginianus) with lyophilized chronic wasting disease prion particulate complexed to montmorillonite clay.
PloS one , 2013 | Pubmed ID: 23671598
Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease.
International immunology Dec, 2013 | Pubmed ID: 24038599
Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons.
PloS one , 2014 | Pubmed ID: 24760020
Prions--not your immunologist's pathogen.
PLoS pathogens Feb, 2015 | Pubmed ID: 25695738
A brief history of prions.
Pathogens and disease Dec, 2015 | Pubmed ID: 26449713
Detection and Quantification of CWD Prions in Fixed Paraffin Embedded Tissues by Real-Time Quaking-Induced Conversion.
Scientific reports , 2016 | Pubmed ID: 27157060
Dietary magnesium and copper affect survival time and neuroinflammation in chronic wasting disease.
Prion May, 2016 | Pubmed ID: 27216881
Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice.
Frontiers in microbiology , 2016 | Pubmed ID: 27933048
Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification.
mSphere , 2017 | Pubmed ID: 28144628
Endogenous Brain Lipids Inhibit Prion Amyloid Formation .
Journal of virology May, 2017 | Pubmed ID: 28202758
Pathways of Prion Spread during Early Chronic Wasting Disease in Deer.
Journal of virology May, 2017 | Pubmed ID: 28250130
Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2017 | Pubmed ID: 29070671
Relative Impact of Complement Receptors CD21/35 (Cr2/1) on Scrapie Pathogenesis in Mice.
mSphere , 2017 | Pubmed ID: 29202042
Lipopeptide Delivery of siRNA to the Central Nervous System.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30838631
Chronic Wasting Disease in Cervids: Implications for Prion Transmission to Humans and Other Animal Species.
mBio Jul, 2019 | Pubmed ID: 31337719
siRNA Therapeutics for Protein Misfolding Diseases of the Central Nervous System.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 33928585
Tissue-specific biochemical differences between chronic wasting disease prions isolated from free-ranging white-tailed deer (Odocoileus virginianus).
The Journal of biological chemistry Apr, 2022 | Pubmed ID: 35304100
Adipose-derived mesenchymal stromal cells decrease prion-induced glial inflammation in vitro.
Scientific reports Dec, 2022 | Pubmed ID: 36581683
A multiplexed, paired-pooled droplet digital PCR assay for detection of SARS-CoV-2 in saliva.
Scientific reports Feb, 2023 | Pubmed ID: 36813822
Intranasally delivered mesenchymal stromal cells decrease glial inflammation early in prion disease.
Frontiers in neuroscience , 2023 | Pubmed ID: 37250395
1Prion Research Center, Colorado State University,
2Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University,
3Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University
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