Douglas Grossman

Amifostine aminothiols and protection of keratinocyte apoptosis and DNA damage.

Apoptosis regulators and responses in human melanocytic and keratinocytic cells.

Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression.

Metastatic melanoma in pregnancy: risk of transplacental metastases in the infant.

Phospholipid scramblase 3 controls mitochondrial structure, function, and apoptotic response.

Novel application of a fibrin cell block method to evaluate melanocytic cell populations.

Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells.

Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine.

Vulvar melanoma: diffuse melanosis and metastasis to the placenta.

Proliferation, apoptosis, and survivin expression in keratinocytic neoplasms and hyperplasias.

UVB-induced apoptosis drives clonal expansion during skin tumor development.

Imatinib mesylate for melanoma: will a new target be revealed?

Colonization of adjacent stem cell compartments by mutant keratinocytes.

Proliferation, apoptosis, and survivin expression in a spectrum of melanocytic nevi.

Nevus distribution in a Utah melanoma kindred with a temperature-sensitive CDKN2A mutation.

Keratinocyte apoptosis in epidermal development and disease.

Melanoma genetics: a review of genetic factors and clinical phenotypes in familial melanoma.

Activation of dual apoptotic pathways in human melanocytes and protection by survivin.

Proteolytic cleavage of Livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspase.

Phosphorylation of mitochondrial phospholipid scramblase 3 by protein kinase C-delta induces its activation and facilitates mitochondrial targeting of tBid.

Absence of senescence-associated beta-galactosidase activity in human melanocytic nevi in vivo.

Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice.

Predominant formation of heavily pigmented dermal melanocytomas resembling 'animal-type' melanomas in hepatocyte growth factor (C57BL/6 x C3H)F1 mice following neonatal UV irradiation.

Digital dermoscopic monitoring of atypical nevi in patients at risk for melanoma.

N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of ultraviolet-induced melanoma in mice.

Survivin repression by p53, Rb and E2F2 in normal human melanocytes.

Increased melanocytic nevi and nevus density in a G-34T CDKN2A/p16 melanoma-prone pedigree.

Role of phospholipid scramblase 3 in the regulation of tumor necrosis factor-alpha-induced apoptosis.

Sampling of melanocytic nevi for research purposes: a prospective, pilot study to determine effect on diagnosis.

The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells.

Strategies for early melanoma detection: Approaches to the patient with nevi.

Use of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress: towards a novel paradigm for melanoma chemoprevention.

Low rates of clinical recurrence after biopsy of benign to moderately dysplastic melanocytic nevi.

Comparative analysis of total body and dermatoscopic photographic monitoring of nevi in similar patient populations at risk for cutaneous melanoma.

Survivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation.

Failure to compare dermoscopy findings of pigmented lesions on your patient: Comment on "Dermoscopy of patients with multiple nevi".

A decade of melanomas: identification of factors associated with delayed detection in an academic group practice.

Role of the apoptotic and mitotic regulator survivin in melanoma.

The dysplastic nevus: from historical perspective to management in the modern era: part I. Historical, histologic, and clinical aspects.

The dysplastic nevus: from historical perspective to management in the modern era: part II. Molecular aspects and clinical management.

Sentinel lymph node biopsy for melanoma in pregnant women.

Surgical margins for melanoma in situ.

Familial melanoma-associated mutations in p16 uncouple its tumor-suppressor functions.

Selenium for the prevention of cutaneous melanoma.

Commentary: transecting melanomas: does it matter?

Role of melanin in melanocyte dysregulation of reactive oxygen species.

Survivin promotion of melanoma metastasis requires upregulation of α5 integrin.

Skin self-examinations and visual identification of atypical nevi: comparing individual and crowdsourcing approaches.

Aspirin and other NSAIDs as chemoprevention agents in melanoma.

Adequacy of 5-mm surgical excision margins for non-lentiginous melanoma in situ.

Addressing the knowledge gap in clinical recommendations for management and complete excision of clinically atypical nevi/dysplastic nevi: Pigmented Lesion Subcommittee consensus statement.

Predictive value of biopsy specimens suspicious for melanoma: support for 6-mm criterion in the ABCD rule.

A safe and efficient model for ultraviolet radiation-induced herpes simplex labialis.

Practical application of new technologies for melanoma diagnosis: Part I. Noninvasive approaches.

Practical application of new technologies for melanoma diagnosis: Part II. Molecular approaches.

Reduction in nevus biopsies in patients monitored by total body photography.

A phase I study of intratumoral ipilimumab and interleukin-2 in patients with advanced melanoma.

Development of an Educational Program Integrating Concepts of Genetic Risk and Preventive Strategies for Children with a Family History of Melanoma.

A Phase II Randomized Placebo-Controlled Trial of Oral N-acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress In Vivo.