Department of Pediatrics
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Churg-Strauss syndrome in a 7-year-old receiving montelukast and inhaled corticosteroids.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology Feb, 2003 | Pubmed ID: 12602680
Rituximab therapy for multisystem autoimmune diseases in pediatric patients.
The Journal of pediatrics Nov, 2003 | Pubmed ID: 14615729
Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology Oct, 2003 | Pubmed ID: 14641613
Antibiotic desensitization for the allergic patient: 5 years of experience and practice.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology Apr, 2004 | Pubmed ID: 15104194
Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes.
The Journal of clinical investigation Sep, 2005 | Pubmed ID: 16110329
Primary immune deficiencies presenting in adults: seven years of experience from Iran.
Journal of clinical immunology Jul, 2005 | Pubmed ID: 16133995
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution.
Science (New York, N.Y.) Mar, 2006 | Pubmed ID: 16556845
Towards subtlety: understanding the role of Toll-like receptor signaling in susceptibility to human infections.
Clinical immunology (Orlando, Fla.) Jul, 2006 | Pubmed ID: 16563867
Detection of a novel nonsense mutation in the interleukin 2 receptor gamma gene causing X-linked severe combined immunodeficiency.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology Apr, 2006 | Pubmed ID: 16680939
IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2006 | Pubmed ID: 17114497
Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection.
Clinical immunology (Orlando, Fla.) Mar, 2007 | Pubmed ID: 17157070
Common human Toll-like receptor 4 polymorphisms--role in susceptibility to respiratory syncytial virus infection and functional immunological relevance.
Clinical immunology (Orlando, Fla.) Jun, 2007 | Pubmed ID: 17449325
Recurrent systemic pneumococcal disease and IRAK4 deficiency.
The Pediatric infectious disease journal Nov, 2007 | Pubmed ID: 17984826
Commonly invasive serotypes of Streptococcus pneumoniae trigger a reduced innate immune response compared with serotypes rarely responsible for invasive infection.
FEMS immunology and medical microbiology Jun, 2008 | Pubmed ID: 18248437
Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2008 | Pubmed ID: 18490781
Optimizing outcomes of hematopoietic stem cell transplantation for severe combined immunodeficiency.
Clinical immunology (Orlando, Fla.) May, 2009 | Pubmed ID: 19217351
Relative CD4 lymphopenia and a skewed memory phenotype are the main immunologic abnormalities in a child with Omenn syndrome due to homozygous RAG1-C2633T hypomorphic mutation.
Clinical immunology (Orlando, Fla.) Jun, 2009 | Pubmed ID: 19246248
Predictors of early inactive disease in a juvenile idiopathic arthritis cohort: results of a Canadian multicenter, prospective inception cohort study.
Arthritis and rheumatism Aug, 2009 | Pubmed ID: 19644903
Innate immunity.
The Journal of allergy and clinical immunology Feb, 2010 | Pubmed ID: 19932920
Toll-like receptor signaling and pre-eclampsia.
American journal of reproductive immunology (New York, N.Y. : 1989) Jan, 2010 | Pubmed ID: 20059464
Acidification-dependent activation of CD1d-restricted natural killer T cells is intact in cystic fibrosis.
Immunology Jun, 2010 | Pubmed ID: 20102408
Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome.
The Journal of allergy and clinical immunology Feb, 2010 | Pubmed ID: 20159255
Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort.
Arthritis care & research Apr, 2010 | Pubmed ID: 20391508
Epidemiology of asthma: risk factors for development.
Expert review of clinical immunology Jan, 2009 | Pubmed ID: 20476901
TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus.
PloS one Aug, 2010 | Pubmed ID: 20711470
Toll-like receptor gene polymorphisms and preeclampsia risk: a case-control study and data synthesis.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy , 2010 | Pubmed ID: 20818954
TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2010 | Pubmed ID: 21068401
Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients.
The Journal of clinical investigation Jan, 2011 | Pubmed ID: 21123946
Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells.
PloS one , 2010 | Pubmed ID: 21152080
Variables to be controlled in the assessment of blood innate immune responses to Toll-like receptor stimulation.
Journal of immunological methods Mar, 2011 | Pubmed ID: 21277305
The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells.
PloS one Jan, 2011 | Pubmed ID: 21305014
Influence of common non-synonymous Toll-like receptor 4 polymorphisms on bronchopulmonary dysplasia and prematurity in human infants.
PloS one , 2012 | Pubmed ID: 22348075
Staphylococcus aureus nasal septal abscess complicated by extradural abscess in an infant.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale Feb, 2012 | Pubmed ID: 22498276
Role of human TLR4 in respiratory syncytial virus-induced NF-κB activation, viral entry and replication.
Innate immunity Dec, 2012 | Pubmed ID: 22535679
Inflammasome-mediated IL-1β production in humans with cystic fibrosis.
PloS one , 2012 | Pubmed ID: 22649552
Successful approach to treatment of Helicobacter bilis infection in X-linked agammaglobulinemia.
Journal of clinical immunology Dec, 2012 | Pubmed ID: 22843217
Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2012 | Pubmed ID: 23105139
Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2013 | Pubmed ID: 23264659
Functional analysis of the impact of ORMDL3 expression on inflammation and activation of the unfolded protein response in human airway epithelial cells.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology Feb, 2013 | Pubmed ID: 23369242
Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2013 | Pubmed ID: 23487427
IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates.
Journal of leukocyte biology Jun, 2013 | Pubmed ID: 23543769
A new exposure metric for traffic-related air pollution? An analysis of determinants of hopanes in settled indoor house dust.
Environmental health : a global access science source Jun, 2013 | Pubmed ID: 23782977
Neonatal pain-related stress and NFKBIA genotype are associated with altered cortisol levels in preterm boys at school age.
PloS one , 2013 | Pubmed ID: 24066085
Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis.
ACS chemical biology Jan, 2014 | Pubmed ID: 24117378
Pathogen recognition receptor crosstalk in respiratory syncytial virus sensing: a host and cell type perspective.
Trends in microbiology Nov, 2013 | Pubmed ID: 24119913
Severe combined immunodeficiency (SCID) in Canadian children: a national surveillance study.
Journal of clinical immunology Nov, 2013 | Pubmed ID: 24122030
Human primary immunodeficiencies causing defects in innate immunity.
Current opinion in allergy and clinical immunology Dec, 2013 | Pubmed ID: 24126612
An antibiotic-altered microbiota provides fuel for the enteric foe.
Cell research Jan, 2014 | Pubmed ID: 24165893
Combined immunodeficiency associated with homozygous MALT1 mutations.
The Journal of allergy and clinical immunology May, 2014 | Pubmed ID: 24332264
Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2014 | Pubmed ID: 24391215
Hierarchical maturation of innate immune defences in very preterm neonates.
Neonatology , 2014 | Pubmed ID: 24603545
Limitation of TREC-based newborn screening for ZAP70 Severe Combined Immunodeficiency.
Clinical immunology (Orlando, Fla.) Jul, 2014 | Pubmed ID: 24797280
The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort.
Annals of the rheumatic diseases Oct, 2015 | Pubmed ID: 24842571
Assessment of genetic associations between common single nucleotide polymorphisms in RIG-I-like receptor and IL-4 signaling genes and severe respiratory syncytial virus infection in children: a candidate gene case-control study.
PloS one , 2014 | Pubmed ID: 24949794
A novel mouse model of Campylobacter jejuni gastroenteritis reveals key pro-inflammatory and tissue protective roles for Toll-like receptor signaling during infection.
PLoS pathogens Jul, 2014 | Pubmed ID: 25033044
The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.
The Journal of allergy and clinical immunology Aug, 2014 | Pubmed ID: 25087226
Current concepts: host-pathogen interactions in cystic fibrosis airways disease.
European respiratory review : an official journal of the European Respiratory Society Sep, 2014 | Pubmed ID: 25176968
Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes.
European journal of immunology Jan, 2015 | Pubmed ID: 25311115
Dual proteolytic pathways govern glycolysis and immune competence.
Cell Dec, 2014 | Pubmed ID: 25525876
The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study: assessment of environmental exposures.
Journal of exposure science & environmental epidemiology Nov-Dec, 2015 | Pubmed ID: 25805254
Perinatal Exposure to Traffic-Related Air Pollution and Atopy at 1 Year of Age in a Multi-Center Canadian Birth Cohort Study.
Environmental health perspectives Sep, 2015 | Pubmed ID: 25826816
The Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host.
Infection and immunity Jul, 2015 | Pubmed ID: 25895966
The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort.
Annals of the rheumatic diseases Jun, 2016 | Pubmed ID: 25985972
The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma.
Thorax Oct, 2015 | Pubmed ID: 26069286
Amino Acid-Dependent Attenuation of Toll-like Receptor Signaling by Peptide-Gold Nanoparticle Hybrids.
ACS nano Jul, 2015 | Pubmed ID: 26083966
Early infancy microbial and metabolic alterations affect risk of childhood asthma.
Science translational medicine Sep, 2015 | Pubmed ID: 26424567
Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease.
Gastroenterology Feb, 2016 | Pubmed ID: 26481854
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.
Nature communications Nov, 2015 | Pubmed ID: 26525107
IRAK-4 deficiency as a cause for familial fatal invasive infection by Streptococcus pneumoniae.
Clinical immunology (Orlando, Fla.) Feb, 2016 | Pubmed ID: 26698383
Outcomes of Respiratory Syncytial Virus Immunoprophylaxis in Infants Using an Abbreviated Dosing Regimen of Palivizumab.
JAMA pediatrics Feb, 2016 | Pubmed ID: 26720836
Presence of Archaea in the Indoor Environment and Their Relationships with Housing Characteristics.
Microbial ecology Aug, 2016 | Pubmed ID: 27098176
Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation.
Clinical immunology (Orlando, Fla.) 07, 2016 | Pubmed ID: 27109639
A humanized microbiota mouse model of ovalbumin-induced lung inflammation.
Gut microbes Jul, 2016 | Pubmed ID: 27115049
Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index.
JAMA pediatrics Jul, 2016 | Pubmed ID: 27159792
High fecal IgA is associated with reduced Clostridium difficile colonization in infants.
Microbes and infection Sep, 2016 | Pubmed ID: 27235197
Exome Sequencing and the Management of Neurometabolic Disorders.
The New England journal of medicine Jun, 2016 | Pubmed ID: 27276562
Cognitive Enhancement in Infants Associated with Increased Maternal Fruit Intake During Pregnancy: Results from a Birth Cohort Study with Validation in an Animal Model.
EBioMedicine Jun, 2016 | Pubmed ID: 27428442
The hygiene hypothesis: current perspectives and future therapies.
ImmunoTargets and therapy , 2015 | Pubmed ID: 27471720
Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma.
Clinical science (London, England : 1979) Dec, 2016 | Pubmed ID: 27634868
Harmonization of Food-Frequency Questionnaires and Dietary Pattern Analysis in 4 Ethnically Diverse Birth Cohorts.
The Journal of nutrition Nov, 2016 | Pubmed ID: 27708121
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function.
The Journal of clinical investigation Nov, 2016 | Pubmed ID: 27721237
Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells.
Biomaterials Dec, 2016 | Pubmed ID: 27728817
Endoplasmic Reticulum Stress and Chemokine Production in Cystic Fibrosis Airway Cells: Regulation by STAT3 Modulation.
The Journal of infectious diseases Jan, 2017 | Pubmed ID: 27799352
The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus.
Clinical immunology (Orlando, Fla.) Feb, 2017 | Pubmed ID: 28043923
Asthma and the microbiome: defining the critical window in early life.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology , 2017 | Pubmed ID: 28077947
JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome.
The Journal of allergy and clinical immunology Jun, 2017 | Pubmed ID: 28111307
Ethnic and diet-related differences in the healthy infant microbiome.
Genome medicine Mar, 2017 | Pubmed ID: 28356137
Exposure to household furry pets influences the gut microbiota of infant at 3-4 months following various birth scenarios.
Microbiome Apr, 2017 | Pubmed ID: 28381231
Respiratory syncytial virus-neutralizing serum antibody titers in infants following palivizumab prophylaxis with an abbreviated dosing regimen.
PloS one , 2017 | Pubmed ID: 28437470
Fecal Short-Chain Fatty Acid Variations by Breastfeeding Status in Infants at 4 Months: Differences in Relative versus Absolute Concentrations.
Frontiers in nutrition , 2017 | Pubmed ID: 28443284
Breastfeeding, maternal asthma and wheezing in the first year of life: a longitudinal birth cohort study.
The European respiratory journal May, 2017 | Pubmed ID: 28461293
Timing of food introduction and development of food sensitization in a prospective birth cohort.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology May, 2017 | Pubmed ID: 28557044
In vivo immune signatures of healthy human pregnancy: Inherently inflammatory or anti-inflammatory?
PloS one , 2017 | Pubmed ID: 28636613
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