Dietmar W. Hutmacher

Computational fluid dynamics for improved bioreactor design and 3D culture.

Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture.

Tissue engineering of articular cartilage with biomimetic zones.

The challenge of establishing preclinical models for segmental bone defect research.

Translating tissue engineering technology platforms into cancer research.

Strategies for zonal cartilage repair using hydrogels.

Establishment of a preclinical ovine model for tibial segmental bone defect repair by applying bone tissue engineering strategies.

Can tissue engineering concepts advance tumor biology research?

Coating of biomaterial scaffolds with the collagen-mimetic peptide GFOGER for bone defect repair.

Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research.

Biomaterials offer cancer research the third dimension.

Runx2 overexpression in bone marrow stromal cells accelerates bone formation in critical-sized femoral defects.

Colonization and osteogenic differentiation of different stem cell sources on electrospun nanofiber meshes.

Ovine bone- and marrow-derived progenitor cells and their potential for scaffold-based bone tissue engineering applications in vitro and in vivo.

Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment.

Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells.

An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects.

Melt electrospinning.

Custom-made composite scaffolds for segmental defect repair in long bones.

Interactions between human osteoblasts and prostate cancer cells in a novel 3D in vitro model.

Silk fibroin in ocular tissue reconstruction.

Cell sourcing for bone tissue engineering: amniotic fluid stem cells have a delayed, robust differentiation compared to mesenchymal stem cells.

Direct writing by way of melt electrospinning.

A biphasic scaffold design combined with cell sheet technology for simultaneous regeneration of alveolar bone/periodontal ligament complex.

Direct fabrication as a patient-targeted therapeutic in a clinical environment.

A tissue engineering solution for segmental defect regeneration in load-bearing long bones.

Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment.

Combined expression of KLK4, KLK5, KLK6, and KLK7 by ovarian cancer cells leads to decreased adhesion and paclitaxel-induced chemoresistance.

Stage-specific embryonic antigen-4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells.

Delineating breast cancer cell interactions with engineered bone microenvironments.

Dermal fibroblast infiltration of poly(ε-caprolactone) scaffolds fabricated by melt electrospinning in a direct writing mode.

Using extracellular matrix for regenerative medicine in the spinal cord.

Effect of culture conditions and calcium phosphate coating on ectopic bone formation.

Effect of preculture and loading on expression of matrix molecules, matrix metalloproteinases, and cytokines by expanded osteoarthritic chondrocytes.

A multiscale road map of cancer spheroids--incorporating experimental and mathematical modelling to understand cancer progression.

A bioengineered 3D ovarian cancer model for the assessment of peptidase-mediated enhancement of spheroid growth and intraperitoneal spread.

Chondrocyte redifferentiation and construct mechanical property development in single-component photocrosslinkable hydrogels.

Nanofiber orientation and surface functionalization modulate human mesenchymal stem cell behavior in vitro.

A road map for a tissue engineering concept for restoring structure and function after limb loss.

Immunosuppressive properties of mesenchymal stromal cell cultures derived from the limbus of human and rabbit corneas.

Composites for delivery of therapeutics: combining melt electrospun scaffolds with loaded electrosprayed microparticles.

A biomimetic extracellular matrix for cartilage tissue engineering centered on photocurable gelatin, hyaluronic acid and chondroitin sulfate.

Effects of scaffold architecture on cranial bone healing.

Fabrication and in vitro characterization of bioactive glass composite scaffolds for bone regeneration.

Biological performance of a polycaprolactone-based scaffold plus recombinant human morphogenetic protein-2 (rhBMP-2) in an ovine thoracic interbody fusion model.

Perspectives in multiphasic osteochondral tissue engineering.

A polymerase chain reaction-based method for isolating clones from a complimentary DNA library in sheep.

A humanized tissue-engineered in vivo model to dissect interactions between human prostate cancer cells and human bone.

Paracrine interactions between LNCaP prostate cancer cells and bioengineered bone in 3D in vitro culture reflect molecular changes during bone metastasis.

Species-specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone.

Gelatine methacrylamide-based hydrogels: an alternative three-dimensional cancer cell culture system.

Multiphasic construct studied in an ectopic osteochondral defect model.

A tissue-engineered humanized xenograft model of human breast cancer metastasis to bone.

Mimicking breast cancer-induced bone metastasis in vivo: current transplantation models and advanced humanized strategies.

Bacterial comparison of preoperative rinsing and swabbing for oral surgery using 0.2% chlorhexidine.

Melt electrospinning and its technologization in tissue engineering.

New mechanistic insights of integrin β1 in breast cancer bone colonization.

Effect of the sterilization method on the properties of Bombyx mori silk fibroin films.

Hyaluronic acid enhances the mechanical properties of tissue-engineered cartilage constructs.

Engineering of tumor microenvironments.

Melt electrospinning of poly(ε-caprolactone) scaffolds: phenomenological observations associated with collection and direct writing.

Erratum to: Biological performance of a polycaprolactone-based scaffold plus recombinant human morphogenetic protein-2 (rhBMP-2) in an ovine thoracic interbody fusion model.

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage-mediated inflammation in muscle.

Fetal endothelial and mesenchymal progenitors from the human term placenta: potency and clinical potential.

Initial design and physical characterization of a polymeric device for osmosis-driven delayed burst delivery of vaccines.

Sustained regeneration of high-volume adipose tissue for breast reconstruction using computer aided design and biomanufacturing.

Delayed minimally invasive injection of allogenic bone marrow stromal cell sheets regenerates large bone defects in an ovine preclinical animal model.

Multi-parametric hydrogels support 3D in vitro bioengineered microenvironment models of tumour angiogenesis.

Biomaterial science meets computational biology.

Reinforcement of hydrogels using three-dimensionally printed microfibres.

Tie-2 regulates the stemness and metastatic properties of prostate cancer cells.

Tissue engineered humanized bone supports human hematopoiesis in vivo.

BMP delivery complements the guiding effect of scaffold architecture without altering bone microstructure in critical-sized long bone defects: A multiscale analysis.

Convergence of regenerative medicine and synthetic biology to develop standardized and validated models of human diseases with clinical relevance.

Bone Regeneration Based on Tissue Engineering Conceptions - A 21st Century Perspective.

Additive manufacturing in biomedical sciences and the need for definitions and norms.

In vitro and in vivo bone formation potential of surface calcium phosphate-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds.

Growth Factor-Loaded Microparticles for Tissue Engineering: The Discrepancies of In Vitro Characterization Assays.

Functionalization, preparation and use of cell-laden gelatin methacryloyl-based hydrogels as modular tissue culture platforms.

Data for accelerated degradation of calcium phosphate surface-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds.

Quo Vadis Breast Tissue Engineering?

A Validated Preclinical Animal Model for Primary Bone Tumor Research.

Transformation of Breast Reconstruction via Additive Biomanufacturing.

Additive Biomanufacturing: An Advanced Approach for Periodontal Tissue Regeneration.

Polylactides in additive biomanufacturing.

Tissue engineering and regenerative medicine in musculoskeletal oncology.

Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival.

Vascularised bone transfer: History, blood supply and contemporary problems.

Fabrication and Characterization of Decellularized Periodontal Ligament Cell Sheet Constructs.

Endosteal-like extracellular matrix expression on melt electrospun written scaffolds.

3-Dimensional functionalized polycaprolactone-hyaluronic acid hydrogel constructs for bone tissue engineering.

Priming of endothelial colony-forming cells in a mesenchymal niche improves engraftment and vasculogenic potential by initiating mesenchymal transition orchestrated by NOTCH signaling.

Periosteum tissue engineering in an orthotopic in vivo platform.

Antimicrobial and Immunomodulatory Surface-Functionalized Electrospun Membranes for Bone Regeneration.

Engineering a humanized bone organ model in mice to study bone metastases.

Biofabricated soft network composites for cartilage tissue engineering.

Breast Augmentation and Reconstruction from a Regenerative Medicine Point of View: State of the Art and Future Perspectives.

Structural analysis of photocrosslinkable methacryloyl-modified protein derivatives.

3D printed lattices as an activation and expansion platform for T cell therapy.

Scaffold curvature-mediated novel biomineralization process originates a continuous soft tissue-to-bone interface.

Microparticles for Sustained Growth Factor Delivery in the Regeneration of Critically-Sized Segmental Tibial Bone Defects.

Challenges and opportunities in the manufacture and expansion of cells for therapy.

Fetal Bone Marrow-Derived Mesenchymal Stem/Stromal Cells Enhance Humanization and Bone Formation of BMP7 Loaded Scaffolds.

Examination of the foreign body response to biomaterials by nonlinear intravital microscopy.

Mesenchymal stem/stromal cells enhance engraftment, vasculogenic and pro-angiogenic activities of endothelial colony forming cells in immunocompetent hosts.

A Novel 3D Cultured Model for Studying Early Changes in Age-Related Macular Degeneration.

A novel bioreactor system for biaxial mechanical loading enhances the properties of tissue-engineered human cartilage.

Rational Design of Mouse Models for Cancer Research.

Assessment of static and perfusion methods for decellularization of PCL membrane-supported periodontal ligament cell sheet constructs.

Meso-Endothelial Bipotent Progenitors from Human Placenta Display Distinct Molecular and Cellular Identity.

3D printed Polycaprolactone scaffolds with dual macro-microporosity for applications in local delivery of antibiotics.

Melt Electrospinning Writing of Highly Ordered Large Volume Scaffold Architectures.

Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study.

Animal models for bone tissue engineering and modelling disease.

Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.

A Method for Prostate and Breast Cancer Cell Spheroid Cultures Using Gelatin Methacryloyl-Based Hydrogels.

Non-linear optical microscopy and histological analysis of collagen, elastin and lysyl oxidase expression in breast capsular contracture.

The quest for mechanically and biologically functional soft biomaterials via soft network composites.

Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone.

Tissue Engineered Constructs for Periodontal Regeneration: Current Status and Future Perspectives.

Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning.

Nipple Reconstruction: A Regenerative Medicine Approach Using 3D-Printed Tissue Scaffolds.

A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns.

Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone.

Printomics: the high-throughput analysis of printing parameters applied to melt electrowriting.

Tuning mechanical reinforcement and bioactivity of 3D printed ternary nanocomposites by interfacial peptide-polymer conjugates.

A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma.

3D printed dual macro-, microscale porous network as a tissue engineering scaffold with drug delivering function.

Independent Evaluation of Medical-Grade Bioresorbable Filaments for Fused Deposition Modelling/Fused Filament Fabrication of Tissue Engineered Constructs.

A clarion call for understanding regulatory processes for additive manufacturing in the health sector.

Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment.

Biologically Inspired Scaffolds for Heart Valve Tissue Engineering via Melt Electrowriting.

Immunogold FIB-SEM: Combining Volumetric Ultrastructure Visualization with 3D Biomolecular Analysis to Dissect Cell-Environment Interactions.

Recombinant Human Bone Morphogenetic Protein 7 Exerts Osteo-Catabolic Effects on Bone Grafts That Outweigh Its Osteo-Anabolic Capacity.

In vitro disease models 4.0 via automation and high-throughput processing.

Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts.

Investigation of Sustained BMP Delivery in the Prevention of Medication-Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model.

Addressing Patient Specificity in the Engineering of Tumor Models.

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo.

Convergence of Scaffold-Guided Bone Reconstruction and Surgical Vascularization Strategies-A Quest for Axial Vascularization.

A preclinical large-animal model for the assessment of critical-size load-bearing bone defect reconstruction.

Gelatin Methacryloyl Hydrogels Control the Localized Delivery of Albumin-Bound Paclitaxel.

Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis.

Effect of gelatin source and photoinitiator type on chondrocyte redifferentiation in gelatin methacryloyl-based tissue-engineered cartilage constructs.

Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo.

The Patenting and Technological Trends in Hernia Mesh Implants.

Electrospinning and additive manufacturing: converging technologies.

Stromal fibroblasts regulate microvascular-like network architecture in a bioengineered breast tumour angiogenesis model.

Melt Electrowriting of Complex 3D Anatomically Relevant Scaffolds.

Three-dimensional printing in a pandemic: panacea or panic?

A 3D-printed biomaterials-based platform to advance established therapy avenues against primary bone cancers.

Human and mouse bones physiologically integrate in a humanized mouse model while maintaining species-specific ultrastructure.

Hydrogels as Drug Delivery Systems: A Review of Current Characterization and Evaluation Techniques.

Convergence of 3D printed biomimetic wound dressings and adult stem cell therapy.

Convergence of scaffold-guided bone regeneration and RIA bone grafting for the treatment of a critical-sized bone defect of the femoral shaft.

Automated 3D Microphysiometry Facilitates High-Content and Highly Reproducible Oxygen Measurements within 3D Cell Culture Models.

Elucidating the Molecular Mechanisms for the Interaction of Water with Polyethylene Glycol-Based Hydrogels: Influence of Ionic Strength and Gel Network Structure.

Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction.

A Preclinical Animal Model for the Study of Scaffold-Guided Breast Tissue Engineering.

A humanised rat model of osteosarcoma reveals ultrastructural differences between bone and mineralised tumour tissue.

Deciphering the Molecular Mechanism of Water Interaction with Gelatin Methacryloyl Hydrogels: Role of Ionic Strength, pH, Drug Loading and Hydrogel Network Characteristics.

Convergence of Machine Vision and Melt Electrowriting.

In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer.

Tissue engineering of corneal stroma via melt electrowriting.

Scaffold-guided bone regeneration in large volume tibial segmental defects.

A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells.

Engineering a 3D bone marrow adipose composite tissue loading model suitable for studying mechanobiological questions.

Biomechanical Principles of Breast Implants and Current State of Research in Soft Tissue Engineering for Cosmetic Breast Augmentation.

: An Algorithm for Standardization and Automation of Compression Test Analysis.

Gelatin Methacryloyl Hydrogels for the Localized Delivery of Cefazolin.

Label-free isolation and cultivation of patient-matched human mammary epithelial and stromal cells from normal breast tissue.

Cognitive Bias and Therapy Choice in Breast Reconstruction Surgery Decision-Making.

Bone regeneration exploiting corticoperiosteal tissue transfer in scaffold-guided bone regeneration.