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Clinical Research Division
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Development of pyrazolone and isoxazol-5-one cambinol analogues as sirtuin inhibitors.
Journal of medicinal chemistry Apr, 2014 | Pubmed ID: 24697269
SIR2 suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2017 | Pubmed ID: 28049846
Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2017 | Pubmed ID: 28143937
Fred Hutchinson Cancer Research Center
Vid Leko1,2,
Smitha Sripathy1,
Robin L. Adrianse1,
Taylor Loe1,
Angela Park1,
Uyen Lao1,
Eric J. Foss1,
Marisa S. Bartolomei3,
Antonio Bedalov1,4
1Clinical Research Division, Fred Hutchinson Cancer Research Center,
2Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health,
3Epigenetics Program, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine,
4Departments of Medicine and Biochemistry, University of Washington
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