S'identifier

Taylor Loe

Clinical Research Division

Fred Hutchinson Cancer Research Center

BIOGRAPHY

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PUBLICATIONS

Development of pyrazolone and isoxazol-5-one cambinol analogues as sirtuin inhibitors.

Journal of medicinal chemistry Apr, 2014 | Pubmed ID: 24697269

SIR2 suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences.

Proceedings of the National Academy of Sciences of the United States of America Jan, 2017 | Pubmed ID: 28049846

Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression.

Proceedings of the National Academy of Sciences of the United States of America Feb, 2017 | Pubmed ID: 28143937

INSTITUTIONS

Fred Hutchinson Cancer Research Center

JOVE ARTICLES

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Vid Leko^1,2,

Smitha Sripathy¹,

Robin L. Adrianse¹,

Taylor Loe¹,

Angela Park¹,

Uyen Lao¹,

Eric J. Foss¹,

Marisa S. Bartolomei³,

Antonio Bedalov^1,4

¹Clinical Research Division, Fred Hutchinson Cancer Research Center,

²Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health,

³Epigenetics Program, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine,

⁴Departments of Medicine and Biochemistry, University of Washington

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Taylor Loe

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Clinical Research Division

Fred Hutchinson Cancer Research Center

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Clinical Research Division