Junmin Peng

SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells.

Analysis of ubiquitinated proteome by quantitative mass spectrometry.

Characterizing ubiquitination sites by peptide-based immunoaffinity enrichment.

PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.

Quantitative proteomics to decipher ubiquitin signaling.

Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.

Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron.

Sjogren syndrome antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition.

Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2.

The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis.

Proteomic analysis of postsynaptic density in Alzheimer's disease.

Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity.

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.

A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway.

Identification and characterization of phosphorylation sites within the pregnane X receptor protein.

The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination.

A nano ultra-performance liquid chromatography-high resolution mass spectrometry approach for global metabolomic profiling and case study on drug-resistant multiple myeloma.

Autoregulation of the 26S proteasome by in situ ubiquitination.

Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing.

Integrated approaches for analyzing U1-70K cleavage in Alzheimer's disease.

Global ubiquitination analysis by SILAC in mammalian cells.

JUMP: a tag-based database search tool for peptide identification with high sensitivity and accuracy.

Refined phosphopeptide enrichment by phosphate additive and the analysis of human brain phosphoproteome.

Systematic optimization of long gradient chromatography mass spectrometry for deep analysis of brain proteome.

Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract.

Quantitative protein analysis by mass spectrometry.

Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth.

PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins.

Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.

A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination.

Joint mouse-human phenome-wide association to test gene function and disease risk.

SUMO Pathway Modulation of Regulatory Protein Binding at the Ribosomal DNA Locus in Saccharomyces cerevisiae.

Enhanced Purification of Ubiquitinated Proteins by Engineered Tandem Hybrid Ubiquitin-binding Domains (ThUBDs).

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.

JUMPg: An Integrative Proteogenomics Pipeline Identifying Unannotated Proteins in Human Brain and Cancer Cells.

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.

The C. elegans Taste Receptor Homolog LITE-1 Is a Photoreceptor.

Deep Profiling of Proteome and Phosphoproteome by Isobaric Labeling, Extensive Liquid Chromatography, and Mass Spectrometry.

Extensive Peptide Fractionation and y1 Ion-Based Interference Detection Method for Enabling Accurate Quantification by Isobaric Labeling and Mass Spectrometry.

Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain.

Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation.

Quantitative Phosphoproteomic Analysis of Brain Tissues.

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.

The neoepitope landscape in pediatric cancers.

Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells.

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.

Target-Decoy-Based False Discovery Rate Estimation for Large-Scale Metabolite Identification.

Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo.

Hippo/Mst signalling couples metabolic state and immune function of CD8α dendritic cells.

Isotope Labeling-Assisted Evaluation of Hydrophilic and Hydrophobic Liquid Chromatograph-Mass Spectrometry for Metabolomics Profiling.

Quantitative phosphoproteomic analysis of the molecular substrates of sleep need.

Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome.

Spectral Library Search Improves Assignment of TMT Labeled MS/MS Spectra.

BDNF inhibits neurodegenerative disease-associated asparaginyl endopeptidase activity via phosphorylation by AKT.

Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11.

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a.

Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.

Deep Profiling of the Aggregated Proteome in Alzheimer's Disease: From Pathology to Disease Mechanisms.

Deubiquitylase USP9X maintains centriolar satellite integrity by stabilizing pericentriolar material 1 protein.

TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer.

Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1.

Phosphatidic acid generated by PLD2 promotes the plasma membrane recruitment of IQGAP1 and neointima formation.

Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity.

Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles.

Regulation of gene expression by miR-144/451 during mouse erythropoiesis.

ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.

Identification of a Functional Non-coding Variant in the GABA Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research.

Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer's disease.

Corrigendum to "Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles" [379 (2019) 55-64].

Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia.

Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across populations.

Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability.

Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease.

ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.

A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice.

Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes.

Multimodal Imaging of Amyloid Plaques: Fusion of the Single-Probe Mass Spectrometry Image and Fluorescence Microscopy Image.

Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.

Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology.

Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.

An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.

A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3' End Processing Complex.

Novel specialized cell state and spatial compartments within the germinal center.

27-Plex Tandem Mass Tag Mass Spectrometry for Profiling Brain Proteome in Alzheimer's Disease.

Ligand-induced monoubiquitination of BIK1 regulates plant immunity.

JUMPm: A Tool for Large-Scale Identification of Metabolites in Untargeted Metabolomics.

Control of Early B Cell Development by the RNA N-Methyladenosine Methylation.

Toxicoproteomic Profiling of Transgenic Mice Treated with Rifampicin and Isoniazid.

Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease.

Systems immunology: Integrating multi-omics data to infer regulatory networks and hidden drivers of immunity.

Combinatorial expression of GPCR isoforms affects signalling and drug responses.

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis.

Deep Profiling of Microgram-Scale Proteome by Tandem Mass Tag Mass Spectrometry.

Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses.

Antagonistic control of myofiber size and muscle protein quality control by the ubiquitin ligase UBR4 during aging.

Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL).

Global Profiling of Lysine Accessibility to Evaluate Protein Structure Changes in Alzheimer's Disease.

Quantifying Proteome and Protein Modifications in Activated T Cells by Multiplexed Isobaric Labeling Mass Spectrometry.

High-Throughput Profiling of Proteome and Posttranslational Modifications by 16-Plex TMT Labeling and Mass Spectrometry.

An age-downregulated ribosomal RpS28 protein variant regulates the muscle proteome.

Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators.

Structural analysis of the full-length human LRRK2.

Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia.

Global Proteomic Profiling of Pediatric AML: A Pilot Study.

Proteomic landscape of Alzheimer's Disease: novel insights into pathogenesis and biomarker discovery.

Acute depletion of CTCF rewires genome-wide chromatin accessibility.

JUMPt: Comprehensive Protein Turnover Modeling of In Vivo Pulse SILAC Data by Ordinary Differential Equations.