Anthony A. High

Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome.

Sgt1 dimerization is negatively regulated by protein kinase CK2-mediated phosphorylation at Ser361.

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

The E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation.

A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease.

HECT-E3 ligase ETC-1 regulates securin and cyclin B1 cytoplasmic abundance to promote timely anaphase during meiosis in C. elegans.

Hematopoietic progenitor cell lines with myeloid and lymphoid potential.

Identification and characterization of phosphorylation sites within the pregnane X receptor protein.

Quantitative proteomic analysis of the influenza A virus nonstructural proteins NS1 and NS2 during natural cell infection identifies PACT as an NS1 target protein and antiviral host factor.

Integrated approaches for analyzing U1-70K cleavage in Alzheimer's disease.

Quantitative protein analysis by mass spectrometry.

Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination.

Deep Profiling of Proteome and Phosphoproteome by Isobaric Labeling, Extensive Liquid Chromatography, and Mass Spectrometry.

Extensive Peptide Fractionation and y1 Ion-Based Interference Detection Method for Enabling Accurate Quantification by Isobaric Labeling and Mass Spectrometry.

Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins.

Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer's disease.

Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes.

Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.

Deep Profiling of Microgram-Scale Proteome by Tandem Mass Tag Mass Spectrometry.