Claus Johansen

Growth medium-dependent ERK1/2 and AP-1 activity in cultured normal human keratinocytes modulates 1alpha,25-dihydroxyvitamin D3-induced differentiation.

1alpha,25(OH)(2)D(3) regulates NF-kappaB DNA binding activity in cultured normal human keratinocytes through an increase in IkappaBalpha expression.

Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.

Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines.

IL-20 gene expression is induced by IL-1beta through mitogen-activated protein kinase and NF-kappaB-dependent mechanisms.

Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis.

Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect.

The activity of caspase-1 is increased in lesional psoriatic epidermis.

Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases.

Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice.

Inflammasomes and inflammatory caspases in skin inflammation.

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

MK2 regulates the early stages of skin tumor promotion.

The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.

The role of mitogen- and stress-activated protein kinase 1 and 2 in chronic skin inflammation in mice.

Caspase-5 expression is upregulated in lesional psoriatic skin.

Mice lacking MSK1 and MSK2 show reduced skin tumor development in a two-stage chemical carcinogenesis model.

Role of p38 mitogen-activated protein kinase isoforms in murine skin inflammation induced by 12-O-tetradecanoylphorbol 13-acetate.

Regulation of caspase 14 expression in keratinocytes by inflammatory cytokines--a possible link between reduced skin barrier function and inflammation?

Tumor necrosis factor α-mediated induction of interleukin 17C in human keratinocytes is controlled by nuclear factor κB.

Kinetics and differential expression of the skin-related chemokines CCL27 and CCL17 in psoriasis, atopic dermatitis and allergic contact dermatitis.

CCL27 expression is regulated by both p38 MAPK and IKKβ signalling pathways.

Inflammation-induced alterations in the skin barrier function: implications in atopic dermatitis.

IL-20, IL-21 and p40: potential biomarkers of treatment response for ustekinumab.

TNFα- and IL-17A-mediated S100A8 expression is regulated by p38 MAPK.

Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models.

Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin.

Efficacy of ustekinumab in palmoplantar pustulosis and palmoplantar pustular psoriasis.

A Characterization of the expression of 14-3-3 isoforms in psoriasis, basal cell carcinoma, atopic dermatitis and contact dermatitis.

Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK.

IκBζ is a key driver in the development of psoriasis.

IκBζ: A key protein in the pathogenesis of psoriasis.

Measuring serum concentrations of interleukin-33 in atopic dermatitis is associated with potential false positive results.

Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules.

Characterization of TNF-α- and IL-17A-Mediated Synergistic Induction of DEFB4 Gene Expression in Human Keratinocytes through IκBζ.

Leptin deficiency in mice counteracts imiquimod (IMQ)-induced psoriasis-like skin inflammation while leptin stimulation induces inflammation in human keratinocytes.

IL-17F regulates psoriasis-associated genes through IκBζ.

The "Alarmins" HMBG1 and IL-33 Downregulate Structural Skin Barrier Proteins and Impair Epidermal Growth.

TRIM21 is important in the early phase of inflammation in the imiquimod-induced psoriasis-like skin inflammation mouse model.

Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α.

Langerhans cell markers CD1a and CD207 are the most rapidly responding genes in lesional psoriatic skin following adalimumab treatment.

STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes.

Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study.