Department of Dermatology
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Growth medium-dependent ERK1/2 and AP-1 activity in cultured normal human keratinocytes modulates 1alpha,25-dihydroxyvitamin D3-induced differentiation.
Archives of dermatological research Sep, 2003 | Pubmed ID: 12920533
1alpha,25(OH)(2)D(3) regulates NF-kappaB DNA binding activity in cultured normal human keratinocytes through an increase in IkappaBalpha expression.
Archives of dermatological research Oct, 2004 | Pubmed ID: 15372276
Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2006 | Pubmed ID: 16424170
Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines.
The Journal of investigative dermatology Aug, 2006 | Pubmed ID: 16543895
IL-20 gene expression is induced by IL-1beta through mitogen-activated protein kinase and NF-kappaB-dependent mechanisms.
The Journal of investigative dermatology Jun, 2007 | Pubmed ID: 17255956
Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis.
The Journal of investigative dermatology Aug, 2007 | Pubmed ID: 17429437
Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect.
The Journal of investigative dermatology Sep, 2007 | Pubmed ID: 17495961
The activity of caspase-1 is increased in lesional psoriatic epidermis.
The Journal of investigative dermatology Dec, 2007 | Pubmed ID: 17597823
Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases.
Experimental dermatology Jun, 2008 | Pubmed ID: 18081851
Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice.
The Journal of investigative dermatology Apr, 2009 | Pubmed ID: 18987672
Inflammasomes and inflammatory caspases in skin inflammation.
Expert review of molecular diagnostics Nov, 2008 | Pubmed ID: 18999922
The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.
The EMBO journal Aug, 2009 | Pubmed ID: 19590497
MK2 regulates the early stages of skin tumor promotion.
Carcinogenesis Dec, 2009 | Pubmed ID: 19808857
The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.
PloS one Jan, 2010 | Pubmed ID: 20072629
The role of mitogen- and stress-activated protein kinase 1 and 2 in chronic skin inflammation in mice.
Experimental dermatology Feb, 2011 | Pubmed ID: 21166721
Caspase-5 expression is upregulated in lesional psoriatic skin.
The Journal of investigative dermatology Mar, 2011 | Pubmed ID: 21191419
Mice lacking MSK1 and MSK2 show reduced skin tumor development in a two-stage chemical carcinogenesis model.
Cancer investigation Mar, 2011 | Pubmed ID: 21314333
Role of p38 mitogen-activated protein kinase isoforms in murine skin inflammation induced by 12-O-tetradecanoylphorbol 13-acetate.
Acta dermato-venereologica May, 2011 | Pubmed ID: 21336470
Regulation of caspase 14 expression in keratinocytes by inflammatory cytokines--a possible link between reduced skin barrier function and inflammation?
Experimental dermatology Aug, 2011 | Pubmed ID: 21539619
Tumor necrosis factor α-mediated induction of interleukin 17C in human keratinocytes is controlled by nuclear factor κB.
The Journal of biological chemistry Jul, 2011 | Pubmed ID: 21628458
Kinetics and differential expression of the skin-related chemokines CCL27 and CCL17 in psoriasis, atopic dermatitis and allergic contact dermatitis.
Experimental dermatology Oct, 2011 | Pubmed ID: 21707761
CCL27 expression is regulated by both p38 MAPK and IKKβ signalling pathways.
Cytokine Dec, 2011 | Pubmed ID: 21993219
Inflammation-induced alterations in the skin barrier function: implications in atopic dermatitis.
Chemical immunology and allergy , 2012 | Pubmed ID: 22433374
IL-20, IL-21 and p40: potential biomarkers of treatment response for ustekinumab.
Acta dermato-venereologica Mar, 2013 | Pubmed ID: 22930279
TNFα- and IL-17A-mediated S100A8 expression is regulated by p38 MAPK.
Experimental dermatology Jul, 2013 | Pubmed ID: 23800059
Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models.
BMC immunology Nov, 2013 | Pubmed ID: 24245569
Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin.
Experimental dermatology May, 2014 | Pubmed ID: 24628979
Efficacy of ustekinumab in palmoplantar pustulosis and palmoplantar pustular psoriasis.
International journal of dermatology Oct, 2014 | Pubmed ID: 24962808
A Characterization of the expression of 14-3-3 isoforms in psoriasis, basal cell carcinoma, atopic dermatitis and contact dermatitis.
Dermatology reports Aug, 2010 | Pubmed ID: 25386251
Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK.
PloS one , 2015 | Pubmed ID: 26295581
IκBζ is a key driver in the development of psoriasis.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2015 | Pubmed ID: 26460049
IκBζ: A key protein in the pathogenesis of psoriasis.
Cytokine Feb, 2016 | Pubmed ID: 26615569
Measuring serum concentrations of interleukin-33 in atopic dermatitis is associated with potential false positive results.
SpringerPlus , 2016 | Pubmed ID: 26788445
Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules.
Molecular and cellular therapies , 2016 | Pubmed ID: 26819710
Characterization of TNF-α- and IL-17A-Mediated Synergistic Induction of DEFB4 Gene Expression in Human Keratinocytes through IκBζ.
The Journal of investigative dermatology Aug, 2016 | Pubmed ID: 27117051
Leptin deficiency in mice counteracts imiquimod (IMQ)-induced psoriasis-like skin inflammation while leptin stimulation induces inflammation in human keratinocytes.
Experimental dermatology Apr, 2017 | Pubmed ID: 27488462
IL-17F regulates psoriasis-associated genes through IκBζ.
Experimental dermatology Mar, 2017 | Pubmed ID: 27576147
The "Alarmins" HMBG1 and IL-33 Downregulate Structural Skin Barrier Proteins and Impair Epidermal Growth.
Acta dermato-venereologica Mar, 2017 | Pubmed ID: 27868148
TRIM21 is important in the early phase of inflammation in the imiquimod-induced psoriasis-like skin inflammation mouse model.
Experimental dermatology Aug, 2017 | Pubmed ID: 27943421
Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α.
PloS one , 2016 | Pubmed ID: 28005985
Langerhans cell markers CD1a and CD207 are the most rapidly responding genes in lesional psoriatic skin following adalimumab treatment.
Experimental dermatology Sep, 2017 | Pubmed ID: 28109175
STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes.
PloS one , 2017 | Pubmed ID: 28472186
Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study.
Blood Dec, 2017 | Pubmed ID: 29208599
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