Nicholas M. Luscombe

Molecular fossils in the human genome: identification and analysis of the pseudogenes in chromosomes 21 and 22.

Structural genomics: a new era for pharmaceutical research.

GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis.

Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenes.

Protein-DNA interactions: amino acid conservation and the effects of mutations on binding specificity.

The dominance of the population by a selected few: power-law behaviour applies to a wide variety of genomic properties.

Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae.

The transcriptional activity of human Chromosome 22.

ExpressYourself: A modular platform for processing and visualizing microarray data.

Genomic analysis of gene expression relationships in transcriptional regulatory networks.

Distribution of NF-kappaB-binding sites across human chromosome 22.

Prediction of regulatory networks: genome-wide identification of transcription factor targets from gene expression data.

CREB binds to multiple loci on human chromosome 22.

Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs.

Structure and evolution of transcriptional regulatory networks.

Genomic analysis of regulatory network dynamics reveals large topological changes.

GenCompass: a universal system for analysing gene expression for any genome.

Transcriptional networking.

Comprehensive analysis of combinatorial regulation using the transcriptional regulatory network of yeast.

Extrapolating traditional DNA microarray statistics to tiling and protein microarray technologies.

Transcriptional regulatory networks in bacteria: from input signals to output responses.

Transcriptomics and adaptive genomics of the asymptomatic bacteriuria Escherichia coli strain 83972.

Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility.

Genome-wide analysis reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila.

Principles of transcriptional regulation and evolution of the metabolic system in E. coli.

A census of human transcription factors: function, expression and evolution.

Know your limits: assumptions, constraints and interpretation in systems biology.

Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome.

多路复用大规模并行技术表征人类转录因子具有约束力的具体情况。

Comprehensive reanalysis of transcription factor knockout expression data in Saccharomyces cerevisiae reveals many new targets.

Comparative genomics of cyclic-di-GMP signalling in bacteria: post-translational regulation and catalytic activity.

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution.

The nonspecific lethal complex is a transcriptional regulator in Drosophila.

iCLIP predicts the dual splicing effects of TIA-RNA interactions.

Direct and indirect effects of H-NS and Fis on global gene expression control in Escherichia coli.

Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.

An overview of prokaryotic transcription factors : a summary of function and occurrence in bacterial genomes.

Large-scale nuclear architecture and transcriptional control.

The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1.

Comparative genomics suggests differential deployment of linear and branched signaling across bacteria.

A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast.

How do you find transcription factors? Computational approaches to compile and annotate repertoires of regulators for any genome.

SpeCond: a method to detect condition-specific gene expression.

Genomic analysis of DNA binding and gene regulation by homologous nucleoid-associated proteins IHF and HU in Escherichia coli K12.

SpeCond: a method to detect condition-specific gene expression.

Protein-RNA interactions: new genomic technologies and perspectives.