Mira Edgerton

Salivary histatin 5 and human neutrophil defensin 1 kill Candida albicans via shared pathways.

Salivary histatin 5 and its similarities to the other antimicrobial proteins in human saliva.

Calcium blocks fungicidal activity of human salivary histatin 5 through disruption of binding with Candida albicans.

Uptake of the antifungal cationic peptide Histatin 5 by Candida albicans Ssa2p requires binding to non-conventional sites within the ATPase domain.

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis.

CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model.

Histatin 5 uptake by Candida albicans utilizes polyamine transporters Dur3 and Dur31 proteins.

Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis.

Candida albicans flu1-mediated efflux of salivary histatin 5 reduces its cytosolic concentration and fungicidal activity.

Histatin 5 resistance of Candida glabrata can be reversed by insertion of Candida albicans polyamine transporter-encoding genes DUR3 and DUR31.

Histatin 5-spermidine conjugates have enhanced fungicidal activity and efficacy as a topical therapeutic for oral candidiasis.

Iron-responsive chromatin remodelling and MAPK signalling enhance adhesion in Candida albicans.

How does it kill?: understanding the candidacidal mechanism of salivary histatin 5.

Iron binding modulates candidacidal properties of salivary histatin 5.

Candida albicans Cek1 mitogen-activated protein kinase signaling enhances fungicidal activity of salivary histatin 5.

Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis.

Candida albicans Shed Msb2 and Host Mucins Affect the Candidacidal Activity of Salivary Hst 5.

Innate Immunity and Saliva in Candida albicans-mediated Oral Diseases.

Signalling mucin Msb2 Regulates adaptation to thermal stress in Candida albicans.

Candida glabrata Binding to Candida albicans Hyphae Enables Its Development in Oropharyngeal Candidiasis.

Human Salivary Protein Histatin 5 Has Potent Bactericidal Activity against ESKAPE Pathogens.

Structural Characterization of Histatin 5-Spermidine Conjugates: A Combined Experimental and Theoretical Study.

Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition.

An acquired mechanism of antifungal drug resistance simultaneously enables Candida albicans to escape from intrinsic host defenses.

Fluconazole-Resistant Candida auris Is Susceptible to Salivary Histatin 5 Killing and to Intrinsic Host Defenses.

Real-Time Approach to Flow Cell Imaging of Candida albicans Biofilm Development.

Salivary metals, age, and gender correlate with cultivable oral carriage levels.

Methodologies for and evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

Ras1 inactivation increases resistance to phagosomal killing by human neutrophils.