Nancy R. Manley

One for all and all for one: thymic epithelial stem cells and regeneration.

Stage-specific changes in fetal thymocyte proliferation during the CD4-8- to CD4+8+ transition in wild type, Rag1-/-, and Hoxa3,Pax1 mutant mice.

A developmental look at thymus organogenesis: where do the non-hematopoietic cells in the thymus come from?

New serum-free in vitro culture technique for midgestation mouse embryos.

A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation.

Developing a new paradigm for thymus organogenesis.

Functional evidence for a single endodermal origin for the thymic epithelium.

In vivo and in vitro assays of thymic organogenesis.

Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.

Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs.

Bmp4 and Noggin expression during early thymus and parathyroid organogenesis.

Lack of Foxp3 function and expression in the thymic epithelium.

Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia.

Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus.

Atypical memory phenotype T cells with low homeostatic potential and impaired TCR signaling and regulatory T cell function in Foxn1Delta/Delta mutant mice.

T cell development from kit-negative progenitors in the Foxn1Delta/Delta mutant thymus.

Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis.

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner.

Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity.

Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryos.

An ancient gene network is co-opted for teeth on old and new jaws.

An evolutionary perspective on the mechanisms of immunosenescence.

Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis.

Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas.

Mouse and zebrafish Hoxa3 orthologues have nonequivalent in vivo protein function.

EphB-ephrin-B2 interactions are required for thymus migration during organogenesis.

Transcriptional regulation of thymus organogenesis and thymic epithelial cell differentiation.

Impaired thymic selection and abnormal antigen-specific T cell responses in Foxn1(Δ/Δ) mutant mice.

Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions.

Mechanisms of thymus organogenesis and morphogenesis.