Department of Cell Biology and Virology
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Identification of two nuclear import signals in the alpha-gene product ICP22 of herpes simplex virus 1.
Virology Apr, 2002 | Pubmed ID: 12033795
CD83 on dendritic cells: more than just a marker for maturation.
Trends in immunology Jun, 2002 | Pubmed ID: 12072358
Screening assay for the identification of deoxyhypusine synthase inhibitors.
Journal of biomolecular screening Aug, 2004 | Pubmed ID: 15296643
Blockage of CRM1-dependent nuclear export of the adenovirus type 5 early region 1B 55-kDa protein augments oncogenic transformation of primary rat cells.
Oncogene Jan, 2005 | Pubmed ID: 15480414
Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy.
The Journal of clinical investigation Jan, 2005 | Pubmed ID: 15630446
Expression of CD83 is regulated by HuR via a novel cis-active coding region RNA element.
The Journal of biological chemistry Apr, 2006 | Pubmed ID: 16484227
Stimulated expression of mRNAs in activated T cells depends on a functional CRM1 nuclear export pathway.
Journal of molecular biology May, 2006 | Pubmed ID: 16580684
Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1.
The Journal of biological chemistry Jul, 2006 | Pubmed ID: 16704975
Inhibition of multidrug-resistant HIV-1 by interference with cellular S-adenosylmethionine decarboxylase activity.
The Journal of infectious diseases Sep, 2006 | Pubmed ID: 16941339
Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach.
Blood Feb, 2007 | Pubmed ID: 17008552
The strength of the HIV-1 3' splice sites affects Rev function.
Retrovirology , 2006 | Pubmed ID: 17144911
Analysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expression.
The Journal of biological chemistry Feb, 2007 | Pubmed ID: 17178712
A minimal uORF within the HIV-1 vpu leader allows efficient translation initiation at the downstream env AUG.
Virology Jul, 2007 | Pubmed ID: 17331561
Intranuclear targeting and nuclear export of the adenovirus E1B-55K protein are regulated by SUMO1 conjugation.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2007 | Pubmed ID: 17428914
Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.
Bioorganic & medicinal chemistry Sep, 2007 | Pubmed ID: 17591443
HIV-1 proviral DNA excision using an evolved recombinase.
Science (New York, N.Y.) Jun, 2007 | Pubmed ID: 17600219
In search of novel agents for therapy of tropical diseases and human immunodeficiency virus.
Journal of medicinal chemistry Jan, 2008 | Pubmed ID: 18159921
The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase.
Parasitology research May, 2008 | Pubmed ID: 18256853
[Eradication instead of only inhibiting. Is a totally new anti-HIV strategy evolving? (interview by Waldtraud Paukstadt)].
MMW Fortschritte der Medizin Apr, 2008 | Pubmed ID: 19024924
Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression.
European journal of immunology Jan, 2009 | Pubmed ID: 19130553
The nuclear pore component Nup358 promotes transportin-dependent nuclear import.
Journal of cell science Apr, 2009 | Pubmed ID: 19299463
The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19451623
The karyopherin CRM1 is required for dendritic cell maturation.
Immunobiology May, 2010 | Pubmed ID: 19545931
Sustained virological response after early antiviral treatment of acute hepatitis C virus and HIV coinfection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Aug, 2009 | Pubmed ID: 19580412
Down-regulation of hypusine biosynthesis in Plasmodium by inhibition of S-adenosyl-methionine-decarboxylase.
Amino acids Feb, 2010 | Pubmed ID: 19949824
A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells.
PloS one , 2010 | Pubmed ID: 20179761
Revisiting an old acquaintance: role for eIF5A in diabetes.
The Journal of clinical investigation Jun, 2010 | Pubmed ID: 20501953
SeLOX--a locus of recombination site search tool for the detection and directed evolution of site-specific recombination systems.
Nucleic acids research Jul, 2010 | Pubmed ID: 20529878
In vitro evolution and analysis of HIV-1 LTR-specific recombinases.
Methods (San Diego, Calif.) Jan, 2011 | Pubmed ID: 20600935
Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease.
Journal of virology Feb, 2011 | Pubmed ID: 21047964
Gene therapy strategies: can we eradicate HIV?
Current HIV/AIDS reports Jun, 2011 | Pubmed ID: 21331536
Preventing fusarium head blight of wheat and cob rot of maize by inhibition of fungal deoxyhypusine synthase.
Molecular plant-microbe interactions : MPMI May, 2011 | Pubmed ID: 21463208
Herpes simplex virus immediate-early protein ICP0 is targeted by SIAH-1 for proteasomal degradation.
Journal of virology Aug, 2011 | Pubmed ID: 21632771
Functional characterization of the HuR:CD83 mRNA interaction.
PloS one , 2011 | Pubmed ID: 21829725
Post-transcriptional regulation of CD83 expression by AUF1 proteins.
Nucleic acids research Jan, 2013 | Pubmed ID: 23161671
Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach.
Nucleic acids research Feb, 2013 | Pubmed ID: 23275541
A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation.
Disease models & mechanisms Aug, 2014 | Pubmed ID: 24832488
Kit regulates HSC engraftment across the human-mouse species barrier.
Cell stem cell Aug, 2014 | Pubmed ID: 25017720
mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5.
Nucleic acids research Jun, 2015 | Pubmed ID: 25964300
Biological Relevance and Therapeutic Potential of the Hypusine Modification System.
The Journal of biological chemistry Jul, 2015 | Pubmed ID: 26037925
Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration.
Chemistry & biology Jun, 2015 | Pubmed ID: 26051216
Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.
Nature biotechnology Apr, 2016 | Pubmed ID: 26900663
Posttranslational hypusination of the eukaryotic translation initiation factor-5A regulates Fusarium graminearum virulence.
Scientific reports Apr, 2016 | Pubmed ID: 27098988
Cre Recombinase and Other Tyrosine Recombinases.
Chemical reviews 10, 2016 | Pubmed ID: 27163859
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