Lucy Liaw

Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction.

Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo.

Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification.

Notch activation suppresses fibroblast growth factor-dependent cellular transformation.

Alterations of arterial physiology in osteopontin-null mice.

Improved analysis of the vascular response to arterial ligation using a multivariate approach.

The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation.

Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments.

Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.

Variable recombination efficiency in responder transgenes activated by Cre recombinase in the vasculature.

Selective expression of an aP2/Fatty Acid Binding Protein 4-Cre transgene in non-adipogenic tissues during embryonic development.

A novel mechanism of transcriptional repression of p27kip1 through Notch/HRT2 signaling in vascular smooth muscle cells.

Inhibition of breast cancer cell adhesion and bone metastasis by the extracellular adherence protein of Staphylococcus aureus.

Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.

Widespread delta-like-1 expression in normal adult mouse tissue and injured endothelium is reflected by expression of the Dll1LacZ locus.

Development of fragment-specific osteopontin antibodies and ELISA for quantification in human metastatic breast cancer.

Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site.

Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia.

Cardiovascular and hematopoietic defects associated with Notch1 activation in embryonic Tie2-expressing populations.

Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes.

Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release.

Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame.

Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha.

Antigen-specific induction of osteopontin contributes to the chronification of allergic contact dermatitis.

Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation.

Sprouty1 is a critical regulatory switch of mesenchymal stem cell lineage allocation.

Targeted genome modification in mice using zinc-finger nucleases.

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells.

Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice.

Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts.

Follistatin-like 1 regulates renal IL-1β expression in cisplatin nephrotoxicity.

RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction.

Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling.

Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries.

The miR-143/145 cluster is a novel transcriptional target of Jagged-1/Notch signaling in vascular smooth muscle cells.

Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells.

Tissue-specific expression of Sprouty1 in mice protects against high-fat diet-induced fat accumulation, bone loss and metabolic dysfunction.

Molecular pathways of notch signaling in vascular smooth muscle cells.

Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model?

Notch1 activation in embryonic VE-cadherin populations selectively blocks hematopoietic stem cell generation and fetal liver hematopoiesis.

BMP9 regulates endoglin-dependent chemokine responses in endothelial cells.

Cthrc1, a novel circulating hormone regulating metabolism.

Histone deacetylase activity selectively regulates notch-mediated smooth muscle differentiation in human vascular cells.

Spry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signaling.

Effect of soluble Jagged1-mediated inhibition of Notch signaling on proliferation and differentiation of an adipocyte progenitor cell model.

A receptor-specific function for Notch2 in mediating vascular smooth muscle cell growth arrest through cyclin-dependent kinase inhibitor 1B.

Interactive 3D Analysis of Blood Vessel Trees and Collateral Vessel Volumes in Magnetic Resonance Angiograms in the Mouse Ischemic Hindlimb Model.

Common features of microRNA target prediction tools.

Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo.

Notch signal integration in the vasculature during remodeling.

Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblast.

SLUG is a direct transcriptional repressor of PTEN tumor suppressor.

Fibroblast growth factor signaling in the vasculature.

BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses.

Cthrc1 controls adipose tissue formation, body composition, and physical activity.

Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke.

DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1.

Methods for Analyzing Tumor Angiogenesis in the Chick Chorioallantoic Membrane Model.

Lipid Profiling of In Vitro Cell Models of Adipogenic Differentiation: Relationships With Mouse Adipose Tissues.

Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells.

Suppression of Spry1 inhibits triple-negative breast cancer malignancy by decreasing EGF/EGFR mediated mesenchymal phenotype.

CRISPR/Cas9-Mediated Insertion of loxP Sites in the Mouse Dock7 Gene Provides an Effective Alternative to Use of Targeted Embryonic Stem Cells.

Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.

Exercise reverses pain-related weight asymmetry and differentially modulates trabecular bone microarchitecture in a rat model of osteoarthritis.

Erratum to: Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells.

Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen-mediated changes in cell cycle regulatory circuits.

Development of a 3D bone marrow adipose tissue model.

Characterization of smooth muscle cells from human atherosclerotic lesions and their responses to Notch signaling.

Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation.

Rab27a Regulates Human Perivascular Adipose Progenitor Cell Differentiation.

A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome.