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Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction.
The American journal of pathology Sep, 2001 | Pubmed ID: 11549580
Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo.
The Journal of experimental medicine Oct, 2002 | Pubmed ID: 12391016
Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification.
The American journal of pathology Dec, 2002 | Pubmed ID: 12466120
Notch activation suppresses fibroblast growth factor-dependent cellular transformation.
The Journal of biological chemistry May, 2003 | Pubmed ID: 12598523
Alterations of arterial physiology in osteopontin-null mice.
Arteriosclerosis, thrombosis, and vascular biology Jun, 2003 | Pubmed ID: 12714436
Improved analysis of the vascular response to arterial ligation using a multivariate approach.
The American journal of pathology Jan, 2004 | Pubmed ID: 14695317
The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation.
The Journal of biological chemistry Apr, 2004 | Pubmed ID: 14769803
Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments.
Matrix biology : journal of the International Society for Matrix Biology Nov, 2004 | Pubmed ID: 15579312
Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.
Circulation research Feb, 2005 | Pubmed ID: 15618538
Variable recombination efficiency in responder transgenes activated by Cre recombinase in the vasculature.
Transgenic research Feb, 2006 | Pubmed ID: 16475014
Selective expression of an aP2/Fatty Acid Binding Protein 4-Cre transgene in non-adipogenic tissues during embryonic development.
Transgenic research Oct, 2006 | Pubmed ID: 16952017
A novel mechanism of transcriptional repression of p27kip1 through Notch/HRT2 signaling in vascular smooth muscle cells.
Thrombosis and haemostasis Sep, 2006 | Pubmed ID: 16953280
Inhibition of breast cancer cell adhesion and bone metastasis by the extracellular adherence protein of Staphylococcus aureus.
Biochemical and biophysical research communications May, 2007 | Pubmed ID: 17418809
Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.
The American journal of pathology Sep, 2007 | Pubmed ID: 17675579
Widespread delta-like-1 expression in normal adult mouse tissue and injured endothelium is reflected by expression of the Dll1LacZ locus.
Journal of vascular research , 2008 | Pubmed ID: 17898542
Development of fragment-specific osteopontin antibodies and ELISA for quantification in human metastatic breast cancer.
BMC cancer Jan, 2008 | Pubmed ID: 18237408
Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site.
Circulation research Mar, 2008 | Pubmed ID: 18239137
Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia.
Developmental biology Sep, 2008 | Pubmed ID: 18582454
Cardiovascular and hematopoietic defects associated with Notch1 activation in embryonic Tie2-expressing populations.
Circulation research Aug, 2008 | Pubmed ID: 18617694
Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes.
The American journal of pathology Sep, 2008 | Pubmed ID: 18688026
Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release.
Molecular biology of the cell Nov, 2008 | Pubmed ID: 18784255
Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame.
Cell research Mar, 2009 | Pubmed ID: 19238173
Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha.
Developmental dynamics : an official publication of the American Association of Anatomists Oct, 2009 | Pubmed ID: 19705443
Antigen-specific induction of osteopontin contributes to the chronification of allergic contact dermatitis.
The American journal of pathology Jan, 2010 | Pubmed ID: 20008129
Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation.
The Journal of biological chemistry Jun, 2010 | Pubmed ID: 20368328
Sprouty1 is a critical regulatory switch of mesenchymal stem cell lineage allocation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2010 | Pubmed ID: 20410440
Targeted genome modification in mice using zinc-finger nucleases.
Genetics Oct, 2010 | Pubmed ID: 20628038
The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells.
Genesis (New York, N.Y. : 2000) Sep, 2010 | Pubmed ID: 20645309
Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice.
The American journal of pathology Sep, 2010 | Pubmed ID: 20651245
Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts.
BMC cancer Aug, 2010 | Pubmed ID: 20707913
Follistatin-like 1 regulates renal IL-1β expression in cisplatin nephrotoxicity.
American journal of physiology. Renal physiology Dec, 2010 | Pubmed ID: 20861081
RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2011 | Pubmed ID: 21273559
Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling.
Journal of cellular physiology Nov, 2011 | Pubmed ID: 21302306
Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries.
Genesis (New York, N.Y. : 2000) Aug, 2011 | Pubmed ID: 21557454
The miR-143/145 cluster is a novel transcriptional target of Jagged-1/Notch signaling in vascular smooth muscle cells.
The Journal of biological chemistry Aug, 2011 | Pubmed ID: 21685392
Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells.
Journal of vascular research , 2011 | Pubmed ID: 21832838
Tissue-specific expression of Sprouty1 in mice protects against high-fat diet-induced fat accumulation, bone loss and metabolic dysfunction.
The British journal of nutrition Sep, 2012 | Pubmed ID: 22142492
Molecular pathways of notch signaling in vascular smooth muscle cells.
Frontiers in physiology , 2012 | Pubmed ID: 22509166
Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model?
The journal of trauma and acute care surgery Aug, 2012 | Pubmed ID: 22846954
Notch1 activation in embryonic VE-cadherin populations selectively blocks hematopoietic stem cell generation and fetal liver hematopoiesis.
Transgenic research Apr, 2013 | Pubmed ID: 22851140
BMP9 regulates endoglin-dependent chemokine responses in endothelial cells.
Blood Nov, 2012 | Pubmed ID: 23018639
Cthrc1, a novel circulating hormone regulating metabolism.
PloS one , 2012 | Pubmed ID: 23056600
Histone deacetylase activity selectively regulates notch-mediated smooth muscle differentiation in human vascular cells.
Journal of the American Heart Association Jun, 2012 | Pubmed ID: 23130137
Spry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signaling.
PloS one , 2013 | Pubmed ID: 23554919
Effect of soluble Jagged1-mediated inhibition of Notch signaling on proliferation and differentiation of an adipocyte progenitor cell model.
Adipocyte Jan, 2012 | Pubmed ID: 23700510
A receptor-specific function for Notch2 in mediating vascular smooth muscle cell growth arrest through cyclin-dependent kinase inhibitor 1B.
Circulation research Sep, 2013 | Pubmed ID: 23965337
Interactive 3D Analysis of Blood Vessel Trees and Collateral Vessel Volumes in Magnetic Resonance Angiograms in the Mouse Ischemic Hindlimb Model.
The open medical imaging journal Oct, 2013 | Pubmed ID: 24563682
Common features of microRNA target prediction tools.
Frontiers in genetics , 2014 | Pubmed ID: 24600468
Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo.
Angiogenesis Jan, 2015 | Pubmed ID: 25249331
Notch signal integration in the vasculature during remodeling.
Vascular pharmacology Nov, 2014 | Pubmed ID: 25464152
Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblast.
Bone Jun, 2015 | Pubmed ID: 25725265
SLUG is a direct transcriptional repressor of PTEN tumor suppressor.
The Prostate Jun, 2015 | Pubmed ID: 25728608
Fibroblast growth factor signaling in the vasculature.
Current atherosclerosis reports Jun, 2015 | Pubmed ID: 25813213
BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses.
PloS one , 2015 | Pubmed ID: 25909848
Cthrc1 controls adipose tissue formation, body composition, and physical activity.
Obesity (Silver Spring, Md.) Aug, 2015 | Pubmed ID: 26148471
Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke.
Glia Dec, 2015 | Pubmed ID: 26148976
DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1.
Arteriosclerosis, thrombosis, and vascular biology Dec, 2015 | Pubmed ID: 26471266
Methods for Analyzing Tumor Angiogenesis in the Chick Chorioallantoic Membrane Model.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 26820962
Lipid Profiling of In Vitro Cell Models of Adipogenic Differentiation: Relationships With Mouse Adipose Tissues.
Journal of cellular biochemistry 09, 2016 | Pubmed ID: 26910604
Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells.
Cancer cell international , 2016 | Pubmed ID: 26973433
Suppression of Spry1 inhibits triple-negative breast cancer malignancy by decreasing EGF/EGFR mediated mesenchymal phenotype.
Scientific reports 03, 2016 | Pubmed ID: 26976794
CRISPR/Cas9-Mediated Insertion of loxP Sites in the Mouse Dock7 Gene Provides an Effective Alternative to Use of Targeted Embryonic Stem Cells.
G3 (Bethesda, Md.) 07, 2016 | Pubmed ID: 27175020
Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.
Arthritis & rheumatology (Hoboken, N.J.) 07, 2017 | Pubmed ID: 28320059
Exercise reverses pain-related weight asymmetry and differentially modulates trabecular bone microarchitecture in a rat model of osteoarthritis.
Life sciences Jul, 2017 | Pubmed ID: 28504116
Erratum to: Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells.
Cancer cell international , 2017 | Pubmed ID: 28507453
Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen-mediated changes in cell cycle regulatory circuits.
Journal of cellular biochemistry 04, 2018 | Pubmed ID: 29105817
Development of a 3D bone marrow adipose tissue model.
Bone Jan, 2019 | Pubmed ID: 29366838
Characterization of smooth muscle cells from human atherosclerotic lesions and their responses to Notch signaling.
Laboratory investigation; a journal of technical methods and pathology Mar, 2019 | Pubmed ID: 29795127
Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2018 | Pubmed ID: 29853569
Rab27a Regulates Human Perivascular Adipose Progenitor Cell Differentiation.
Cardiovascular drugs and therapy 10, 2018 | Pubmed ID: 30105417
A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome.
Cell reports Dec, 2018 | Pubmed ID: 30540952
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