Pierre Magistretti

Genes involved in the astrocyte-neuron lactate shuttle (ANLS) are specifically regulated in cortical astrocytes following sleep deprivation in mice.

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons.

Control of mitochondrial pH by uncoupling protein 4 in astrocytes promotes neuronal survival.

Sustained sleep fragmentation induces sleep homeostasis in mice.

Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect.

Methylglyoxal, the dark side of glycolysis.

Multi-timescale modeling of activity-dependent metabolic coupling in the neuron-glia-vasculature ensemble.

Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments.

Neuroenergetic Response to Prolonged Cerebral Glucose Depletion after Severe Brain Injury and the Role of Lactate.

A cellular perspective on brain energy metabolism and functional imaging.

Embodied memory: unconscious smiling modulates emotional evaluation of episodic memories.

Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues.

Complex regulation of CREB-binding protein by homeodomain-interacting protein kinase 2.

Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio.

Goals in Nutrition Science 2015-2020.

Learning-Induced Gene Expression in the Hippocampus Reveals a Role of Neuron -Astrocyte Metabolic Coupling in Long Term Memory.

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.

Regulation of neuron-astrocyte metabolic coupling across the sleep-wake cycle.

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression.

Sodium signaling and astrocyte energy metabolism.

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure.

A Role for Lactate in the Consolidation of Drug-Related Associative Memories.

Imaging brain aerobic glycolysis as a marker of synaptic plasticity.

Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation.

Lactate release from astrocytes to neurons contributes to cocaine memory formation.

Role of MCT1 and CAII in skeletal muscle pH homeostasis, energetics, and function: insights from MCT1 haploinsufficient mice.

A preclinical model for identifying rats at risk of alcohol use disorder.

Gender-specific alteration of energy balance and circadian locomotor activity in the Crtc1 knockout mouse model of depression.

Inadequate brain glycogen or sleep increases spreading depression susceptibility.

Lactate in the brain: from metabolic end-product to signalling molecule.

Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury.

At the Heart of Genome Editing and Cardiovascular Diseases.

Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate.

Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection.

A Process for Digitizing and Simulating Biologically Realistic Oligocellular Networks Demonstrated for the Neuro-Glio-Vascular Ensemble.

L-Lactate Regulates the Expression of Synaptic Plasticity and Neuroprotection Genes in Cortical Neurons: A Transcriptome Analysis.

The Epistemological Foundations of Freud's Energetics Model.

The Strategic Location of Glycogen and Lactate: From Body Energy Reserve to Brain Plasticity.

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction.

Gangliosides: Treatment Avenues in Neurodegenerative Disease.

Lactate and pyruvate promote oxidative stress resistance through hormetic ROS signaling.