radiosensitivity-of-cancer-stem-cells-in-lung-cancer-cell-lines

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines

The presence of cancer stem cells (CSCs) has been associated with relapse or poor outcomes after radiotherapy. Studying radioresistant CSCs may provide ...

Peking University Cancer Hospital and Institute

Radiotherapy is a major treatment method for patients with non-small cell lung cancer (NSCLC). However, the presence of radioresistant cancer stem cells (CSCs) may be associated with disease relapse or a poor outcome after radiotherapy. Voltage-gated calcium channel α2δ1 subunit (encoded by the gene ) isoform 5 is a marker of CSCs in hepatocellular carcinoma. This study aimed to investigate the radiosensitivity of α2δ1-high cells in NSCLC cell lines.

Jian-Hao Geng

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing),
Department of Radiation Oncology,
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiation Oncology

Peking University Cancer Hospital and Institute

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines