Haiteng Deng

Kinetic and mechanistic studies of p38α MAP kinase phosphorylation by MKK6.

Reductive glutaraldehydation of amine groups for identification of protein N-termini.

The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.

Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling.

Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues.

Reproducible enrichment of extracellular heat shock proteins from blood serum using monomeric avidin.

Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein.

Structural basis of ultraviolet-B perception by UVR8.

Function and molecular mechanism of acetylation in autophagy regulation.

Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation.

Development of the Fc-III Tagged Protein Expression System for Protein Purification and Detection.

Profiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells.

c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor.

Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.

L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia.

A proposed role for glutamine in cancer cell growth through acid resistance.

The Arabidopsis F-box protein CORONATINE INSENSITIVE1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway.

Flagellar regeneration requires cytoplasmic microtubule depolymerization and kinesin-13.

Oxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperones.

Quantitative analysis of differentially expressed saliva proteins in human immunodeficiency virus type 1 (HIV-1) infected individuals.

Effects of the Fc-III tag on activity and stability of green fluorescent protein and human muscle creatine kinase.

Structural insights into the N-terminal GIY-YIG endonuclease activity of Arabidopsis glutaredoxin AtGRXS16 in chloroplasts.

Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit.

Azacytidine induces necrosis of multiple myeloma cells through oxidative stress.

Crystal structure of NLRC4 reveals its autoinhibition mechanism.

Structural basis for the regulation of maternal embryonic leucine zipper kinase.

Deacetylase Rpd3 facilitates checkpoint adaptation by preventing Rad53 overactivation.

Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation.

Overexpression of CD38 decreases cellular NAD levels and alters the expression of proteins involved in energy metabolism and antioxidant defense.

Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues.

The gain of hydrogen peroxide resistance benefits growth fitness in mycobacteria under stress.

Structural insights into the assembly of the 30S ribosomal subunit in vivo: functional role of S5 and location of the 17S rRNA precursor sequence.

Systematic analysis of reactivities and fragmentation of glutathione and its isomer GluCysGly.

The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis.

Substrate profiling of glutathione S-transferase with engineered enzymes and matched glutathione analogues.

Down-regulation of Ras-related protein Rab 5C-dependent endocytosis and glycolysis in cisplatin-resistant ovarian cancer cell lines.

Rab8a-AS160-MSS4 Regulatory Circuit Controls Lipid Droplet Fusion and Growth.

FLA8/KIF3B phosphorylation regulates kinesin-II interaction with IFT-B to control IFT entry and turnaround.

Site-specific in situ growth of a cyclized protein-polymer conjugate with improved stability and tumor retention.

Phosphorylation of Atg31 is required for autophagy.

Role for Protein Kinase A in the Neurospora Circadian Clock by Regulating White Collar-Independent frequency Transcription through Phosphorylation of RCM-1.

Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming.

Proteomic Analysis of Drug-Resistant Mycobacteria: Co-Evolution of Copper and INH Resistance.

Analysis of phosphorylation sites on autophagy proteins.

Site-selective in situ growth of fluorescent polymer-antibody conjugates with enhanced antigen detection by signal amplification.

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1.

Gefitinib upregulates death receptor 5 expression to mediate rmhTRAIL-induced apoptosis in Gefitinib-sensitive NSCLC cell line.

Functional Characterization of Sirtuin-like Protein in Mycobacterium smegmatis.

Benzophenone and its analogs bind to human glyoxalase 1.

Effects and mechanism of arsenic trioxide in combination with rmhTRAIL in multiple myeloma.

Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila.

Disruption of microtubules in plants suppresses macroautophagy and triggers starch excess-associated chloroplast autophagy.

Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.

Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease.

The BAH domain of BAHD1 is a histone H3K27me3 reader.

Overexpression of SIRT3 disrupts mitochondrial proteostasis and cell cycle progression.

The Protease Locus of Francisella tularensis LVS Is Required for Stress Tolerance and Infection in the Mammalian Host.

Silencing PRDX3 Inhibits Growth and Promotes Invasion and Extracellular Matrix Degradation in Hepatocellular Carcinoma Cells.

Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein and has multiple functions.

Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma.

Establishment of local searching methods for orbitrap-based high throughput metabolomics analysis.

Proteomic analysis of mTOR inhibition-mediated phosphorylation changes in ribosomal proteins and eukaryotic translation initiation factors.

Serum markers of pre-eclampsia identified on proteomics.

Target and resistance-related proteins of recombinant mutant human tumor necrosis factor-related apoptosis-inducing ligand on myeloma cell lines.

Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length.

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.

Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway.

aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism.

Development of the Double Cyclic Peptide Ligand for Antibody Purification and Protein Detection.

Identification of common and differential mechanisms of glomerulus and tubule senescence in 24-month-old rats by quantitative LC-MS/MS.

Hydrogen peroxide mediated mitochondrial UNG1-PRDX3 interaction and UNG1 degradation.

Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility.

Identification and validation of differentially expressed proteins in epithelial ovarian cancers using quantitative proteomics.

Proteomic Analysis of eIF5B Silencing-Modulated Proteostasis.

ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds.

Chemical Synthesis of Diubiquitin-Based Photoaffinity Probes for Selectively Profiling Ubiquitin-Binding Proteins.

HDAC6-mediated acetylation of lipid droplet-binding protein CIDEC regulates fat-induced lipid storage.

Activity-induced histone modifications govern Neurexin-1 mRNA splicing and memory preservation.

Fasting-induced hormonal regulation of lysosomal function.

Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.

Formation of a Snf1-Mec1-Atg1 Module on Mitochondria Governs Energy Deprivation-Induced Autophagy by Regulating Mitochondrial Respiration.

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.

Comparative Proteomics Reveals Timely Transport into Cilia of Regulators or Effectors as a Mechanism Underlying Ciliary Disassembly.

Comprehensive Myocardial Proteogenomics Profiling Reveals C/EBPα as the Key Factor in the Lipid Storage of ARVC.

Quasi-Dual-Packed-Kerneled Au (2,4-DMBT) Nanoclusters and the Influence of Kernel Packing on the Electrochemical Gap.

Emergence of two distinct subpopulations from Klebsiella pneumoniae grown in the stimulated microgravity environment.

Simple β-lactones are potent irreversible antagonists for strigolactone receptors.

Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.

MtHsp70-CLIC1-pulsed dendritic cells enhance the immune response against ovarian cancer.

Quantitative proteomic analysis of deciduous molars during cap to bell transition in miniature pig.

ISG15 silencing increases cisplatin resistance via activating p53-mediated cell DNA repair.

ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD-Mediated Epithelial-Mesenchymal Transition.

Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis.

PP5 (PPP5C) is a phosphatase of Dvl2.

GATA3 acetylation at K119 by CBP inhibits cell migration and invasion in lung adenocarcinoma.

The Fourth Alloying Mode by Way of Anti-Galvanic Reaction.

Enantioselective and diastereoselective azo-coupling/iminium-cyclizations: a unified strategy for the total syntheses of (-)-psychotriasine and (+)-pestalazine B.

The contribution of chronic intermittent hypoxia to OSAHS: From the perspective of serum extracellular microvesicle proteins.

De novo annotation and characterization of the translatome with ribosome profiling data.

Injury Activates Ca/Calmodulin-Dependent Phosphorylation of JAV1-JAZ8-WRKY51 Complex for Jasmonate Biosynthesis.

Is the kernel-staples match a key-lock match?

Glutaredoxin Deletion Shortens Chronological Life Span in Saccharomyces cerevisiae via ROS-Mediated Ras/PKA Activation.

Structural basis of ubiquitin modification by the Legionella effector SdeA.

Expression and prognostic value of CLIC1 in epithelial ovarian cancer.

Circulating immune complexome analysis identified anti-tubulin-α-1c as an inflammation associated autoantibody with promising diagnostic value for Behcet's Disease.

Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.

A Silver Nanocluster Containing Interstitial Sulfur and Unprecedented Chemical Bonds.

SIRT3 Overexpression Inhibits Growth of Kidney Tumor Cells and Enhances Mitochondrial Biogenesis.

Multiple domains of bacterial and human Lon proteases define substrate selectivity.

Cotton Leaf Curl Multan virus C4 protein suppresses both transcriptional and post-transcriptional gene silencing by interacting with SAM synthetase.

Myeloid-derived suppressor cells inhibit T cell activation through nitrating LCK in mouse cancers.

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.

Kernel Homology in Gold Nanoclusters.

Isotope tracing assisted metabolic profiling: Application to understanding HSP60 silencing mediated tumor progression.

Geminiviral V2 Protein Suppresses Transcriptional Gene Silencing through Interaction with AGO4.

Fcc versus Non-fcc Structural Isomerism of Gold Nanoparticles with Kernel Atom Packing Dependent Photoluminescence.

Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones.

Loss of BAP1 Results in Growth Inhibition and Enhances Mesenchymal-Epithelial Transition in Kidney Tumor Cells.

Development of a dual-functional conjugate of antigenic peptide and Fc-III mimetics (DCAF) for targeted antibody blocking.

HSP60 silencing promotes Warburg-like phenotypes and switches the mitochondrial function from ATP production to biosynthesis in ccRCC cells.

OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin.

Chemical Proteomic Profiling of Bromodomains Enables the Wide-Spectrum Evaluation of Bromodomain Inhibitors in Living Cells.

DNA Damage Activates TGF-β Signaling via ATM-c-Cbl-Mediated Stabilization of the Type II Receptor TβRII.

Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders.

Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation.

HtrA-mediated selective degradation of DNA uptake apparatus accelerates termination of pneumococcal transformation.

HSP60-regulated Mitochondrial Proteostasis and Protein Translation Promote Tumor Growth of Ovarian Cancer.