a-training-testing-system-for-performing-vascular-reconstruction

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Manual vascular reconstruction training is essential for a beginner surgeon. However, an optimal training system for vascular reconstruction in vitro has ...

unveiling-therapeutic-opportunities-with-melanoma-patient-derived

Unveiling Therapeutic Opportunities with Melanoma Patient-derived Organoid Models

With the development of immunotherapy, there is an ongoing need to develop models that can recapitulate the tumor microenvironment of native tumors. While ...

First Affiliated Hospital of Xi'an Jiaotong University

University of Pennsylvania

Neoplasms of perivascular epithelioid cells (PEComas) are characterized by epithelioid to spindle cells with eosinophilic to clear cytoplasm, an intimate relationship with blood vessels, and coexpression of myoid and melanocytic immunohistochemical markers. While most reported hepatic PEComas, such as angiomyolipoma (AML), behave in a benign fashion, emerging PEComas cases without typical characteristics require further clarification. We report a case of primary hepatic perivascular epithelioid cell tumors-not otherwise specified (HPEComas-NOS) with untypical pathological and immunohistochemical features compared to those of the benign hepatic AML cases. HPEComas-NOS may represent a special type of PEComas classified as having "malignant potential" or at "high risk of aggressive behavior", suggesting the need for further clarification of hepatic PEComas and long-term follow-up of patients with HPEComas-NOS.

Hepatic perivascular epithelioid cell tumors-not otherwise specified: a case report.

This study aimed to investigate the incidence and risk factors of portal vein system thrombosis (PVST) in patients with liver cirrhosis after splenectomy and pericardial devascularization.

The incidence and risk factors of portal vein system thrombosis after splenectomy and pericardial devascularization.

Development of organ transplantation is restricted by the discrepancy between the lack of donors and increasing number of patients. The outcome of pediatric donors transplanted into adult recipients especially with donation after circulatory death (DCD) pattern has not been well studied. The aim of this paper is to describe our experience of 3 successful DCD donor child-to-adult liver transplantations lately. Three DCD donors were separately 7, 5, and 8 years old. The ratio between donor graft weight and recipient body weight was 1.42%, 1.00%, and 1.33%, respectively. Ratio between the volume of donor liver and the expected liver volume was 0.65, 0.46, and 0.60. Splenectomy was undertaken for the second recipient according to the portal vein pressure (PVP) which was observed during the operation. Two out of 3 of the recipients suffered with acute kidney injury and got recovered after renal replacement therapy. The first recipient also went through early allograft dysfunction and upper gastrointestinal bleeding. The hospital course of the third recipient was uneventful. After 1 year of follow-up visit, the first and second recipients maintain good quality of life and liver function. The third patient was followed up for 5 months until now and recovered well. DCD child-to-adult liver transplantation should only be used for comparatively matched donor and recipient. PVP should be monitored during the operation. The short-term efficacy is good, but long-term follow-up and clinical study with large sample evaluation are still needed.

Child-to-Adult Liver Transplantation With Donation After Cardiac Death Donors: Three Case Reports.

To introduce a novel laparoscopic training system with a continuously perfused ex-vivo porcine liver for hepatobiliary surgery.

Novel laparoscopic training system with continuously perfused ex-vivo porcine liver for hepatobiliary surgery.

To investigate the potential role of alpha1-adrenoceptor (α1-AR) in the pathogenesis of hepatorenal syndrome.

Xiaogang Zhang

National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine,
Department of Hepatobiliary Surgery

First Affiliated Hospital of Xi'an Jiaotong University

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Unveiling Therapeutic Opportunities with Melanoma Patient-derived Organoid Models

Xiaogang Zhang

National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine,Department of Hepatobiliary Surgery

First Affiliated Hospital of Xi'an Jiaotong University

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Unveiling Therapeutic Opportunities with Melanoma Patient-derived Organoid Models

National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine,
Department of Hepatobiliary Surgery