Patrick Gunning

Selective detection of tyrosine-containing proximally phosphorylated motifs using an antenna-free Tb³⁺ luminescent sensor.

A STAT inhibitor patent review: progress since 2011.

A tool for the selective sequestration of ATP and PPi to aid in-solution phosphopeptide detection assays.

Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics.

Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 1).

Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities.

Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 2).

A selective inhibitor of the UFM1-activating enzyme, UBA5.

Strategies for over-expression and purification of recombinant full length STAT5B in Escherichia coli.

Characterization and application studies of ProxyPhos, a chemosensor for the detection of proximally phosphorylated peptides and proteins in aqueous solutions.

High-throughput thermofluor-based assays for inhibitor screening of STAT SH2 domains.

Structure-activity relationship study of ProxyPhos chemosensors for the detection of proximal phosphorylation and other phosphate species.

ProxyPhos sensors for the detection of negatively charged membranes.

A functional in vitro assay for screening inhibitors of STAT5B phosphorylation.

PI3k and Stat3: Oncogenes that are Required for Gap Junctional, Intercellular Communication.