Geoffrey Chupp

Tissue and T cell distribution of precursor and mature IL-16.

Airway remodeling in asthma.

IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury.

Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium.

Asthma: mechanisms of disease persistence and progression.

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling.

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.

IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.

A chitinase-like protein in the lung and circulation of patients with severe asthma.

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis.

Novel biomarkers in asthma: chemokines and chitinase-like proteins.

The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.

Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema.

Targeting ST2L potentiates CpG-mediated therapeutic effects in a chronic fungal asthma model.

Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function.

Segmental allergen challenge enhances chitinase activity and levels of CCL18 in mild atopic asthma.

Improvement in asthma control and inflammation in children undergoing adenotonsillectomy.

Role of growth arrest-specific gene 6 in the development of fungal allergic airway disease in mice.

IL-6 receptor α defines effector memory CD8+ T cells producing Th2 cytokines and expanding in asthma.

Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40.

Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation.

Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma.

Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study.

Sputum Gene Expression of IL-13 Receptor α2 Chain Correlates with Airflow Obstruction and Helper T-Cell Type 2 Inflammation in Asthma.

Multiparameter Single Cell Profiling of Airway Inflammatory Cells.

Efficacy of mepolizumab add-on therapy on health-related quality of life and markers of asthma control in severe eosinophilic asthma (MUSCA): a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial.

Reappraisal of the clinical effect of mepolizumab - Authors' reply.

Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies.

Characterisation of asthma subgroups associated with circulating YKL-40 levels.

Building an Informed Consent Tool Starting with the Patient: The Patient-Centered Virtual Multimedia Interactive Informed Consent (VIC).

Bronchial Thermoplasty.

Pulmonary artery pseudoaneurysm causing massive hemoptysis in hyperimmunoglobulin E syndrome: a case report.

Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma.

Phenotypes and endotypes of adult asthma: Moving toward precision medicine.