Sebastian Hoffmann

Two new approaches to improve the analysis of BALB/c 3T3 cell transformation assay data.

Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods.

Validation study on the Ocular Irritection assay for eye irritation testing.

Simple clotting test to detect procoagulant abdominal swabs.

LLNA variability: An essential ingredient for a comprehensive assessment of non-animal skin sensitization test methods and strategies.

Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

The Emergence of Systematic Review in Toxicology.

Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase II).

Evidence-Based Toxicology.

A primer on systematic reviews in toxicology.

State-of-the-art and new options to assess T cell activation by skin sensitizers: Cosmetics Europe Workshop.

Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts.

Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database<sup/>.

Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility.

Validation of the CULTEX® Radial Flow System for the assessment of the acute inhalation toxicity of airborne particles.

The HaCaT/THP-1 Cocultured Activation Test (COCAT) for skin sensitization: a study of intra-lab reproducibility and predictivity.

Adaptation of the Systematic Review Framework to the Assessment of Toxicological Test Methods: Challenges and Lessons Learned with the Zebrafish Embryotoxicity Test.

Establishing a health-based recommended occupational exposure limit for nitrous oxide using experimental animal data - A systematic review protocol.

Exposure of 19 substances to lung A549 cells at the air liquid interface or under submerged conditions reveals high correlation between cytotoxicity in vitro and CLP classifications for acute lung toxicity.