Marc N. Hirt
Institute of Experimental Pharmacology and Toxicology
University Medical Center Hamburg-Eppendorf
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Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology.
PloS one , 2011 | Pubmed ID: 22028871
Increased afterload induces pathological cardiac hypertrophy: a new in vitro model.
Basic research in cardiology Nov, 2012 | Pubmed ID: 23099820
Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice.
Journal of molecular and cellular cardiology Oct, 2013 | Pubmed ID: 23896226
Cardiac tissue engineering: state of the art.
Circulation research Jan, 2014 | Pubmed ID: 24436431
Automated analysis of contractile force and Ca2+ transients in engineered heart tissue.
American journal of physiology. Heart and circulatory physiology May, 2014 | Pubmed ID: 24585781
Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation.
Journal of molecular and cellular cardiology Sep, 2014 | Pubmed ID: 24852842
Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology.
Journal of molecular and cellular cardiology Apr, 2015 | Pubmed ID: 25633833
General practitioners' adherence to chronic heart failure guidelines regarding medication: the GP-HF study.
Clinical research in cardiology : official journal of the German Cardiac Society May, 2016 | Pubmed ID: 26552905
DNA methylation in an engineered heart tissue model of cardiac hypertrophy: common signatures and effects of DNA methylation inhibitors.
Basic research in cardiology Jan, 2016 | Pubmed ID: 26680771
Spontaneous Formation of Extensive Vessel-Like Structures in Murine Engineered Heart Tissue.
Tissue engineering. Part A Feb, 2016 | Pubmed ID: 26763667
Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue.
PloS one , 2016 | Pubmed ID: 26840448
Human Engineered Heart Tissue: Analysis of Contractile Force.
Stem cell reports Jul, 2016 | Pubmed ID: 27211213
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Circulation Sep, 2016 | Pubmed ID: 27559042
Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density.
Scientific reports Jul, 2017 | Pubmed ID: 28710467
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats.
Journal of molecular and cellular cardiology Jul, 2018 | Pubmed ID: 29792884
S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue.
Frontiers in physiology , 2018 | Pubmed ID: 30283351
Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors.
ChemMedChem 04, 2019 | Pubmed ID: 30768867
Blockade of miR-140-3p prevents functional deterioration in afterload-enhanced engineered heart tissue.
Scientific reports 08, 2019 | Pubmed ID: 31391475
Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis.
Molecular therapy. Nucleic acids Dec, 2019 | Pubmed ID: 31634682
A magnetics-based approach for fine-tuning afterload in engineered heart tissues.
ACS biomaterials science & engineering Jul, 2019 | Pubmed ID: 31637285
Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue.
Scientific reports Dec, 2019 | Pubmed ID: 31796859
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction.
Nature communications Apr, 2020 | Pubmed ID: 32341350
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