Division of Regenerative Medicine,
Center for Molecular Medicine
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Gene transfer into nonhuman primate hematopoietic stem cells: implications for gene therapy.
Stem cells (Dayton, Ohio) , 2001 | Pubmed ID: 11209087
Introduction of the green fluorescent protein gene into hematopoietic stem cells results in prolonged discrepancy of in vivo transduction levels between bone marrow progenitors and peripheral blood cells in nonhuman primates.
The journal of gene medicine Sep-Oct, 2002 | Pubmed ID: 12221639
Genetic manipulation of primate embryonic and hematopoietic stem cells with simian lentivirus vectors.
Trends in cardiovascular medicine Apr, 2003 | Pubmed ID: 12691674
Improved safety of hematopoietic transplantation with monkey embryonic stem cells in the allogeneic setting.
Stem cells (Dayton, Ohio) Jun, 2006 | Pubmed ID: 16456125
Sustained macroscopic engraftment of cynomolgus embryonic stem cells in xenogeneic large animals after in utero transplantation.
Stem cells and development Apr, 2008 | Pubmed ID: 18447651
Knockout serum replacement (KSR) has a suppressive effect on Sendai virus-mediated transduction of cynomolgus ES cells.
Cloning and stem cells Sep, 2008 | Pubmed ID: 18729764
Variation in the incidence of teratomas after the transplantation of nonhuman primate ES cells into immunodeficient mice.
Cell transplantation , 2008 | Pubmed ID: 19177845
ERas is expressed in primate embryonic stem cells but not related to tumorigenesis.
Cell transplantation , 2009 | Pubmed ID: 19622226
Cotransplantation with MSCs improves engraftment of HSCs after autologous intra-bone marrow transplantation in nonhuman primates.
Experimental hematology Oct, 2009 | Pubmed ID: 19638293
[Generation of high quality induced pluripotent stem cells].
Seikagaku. The Journal of Japanese Biochemical Society Nov, 2011 | Pubmed ID: 22256606
Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development.
Stem cells and development Feb, 2013 | Pubmed ID: 22889279
Generating porcine chimeras using inner cell mass cells and parthenogenetic preimplantation embryos.
PloS one , 2013 | Pubmed ID: 23626746
Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA.
PloS one , 2013 | Pubmed ID: 24130776
MHC-matched induced pluripotent stem cells can attenuate cellular and humoral immune responses but are still susceptible to innate immunity in pigs.
PloS one , 2014 | Pubmed ID: 24927426
Long-term follow-up study on the engraftment of human hematopoietic stem cells in sheep.
Experimental animals , 2014 | Pubmed ID: 25048264
Ultra-Deep Bisulfite Sequencing to Detect Specific DNA Methylation Patterns of Minor Cell Types in Heterogeneous Cell Populations: An Example of the Pituitary Tissue.
PloS one , 2016 | Pubmed ID: 26752725
A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan.
Experimental animals Nov, 2016 | Pubmed ID: 27333841
A Simplified In Vitro Teratoma Assay for Pluripotent Stem Cells Injected Into Rodent Fetal Organs.
Cell medicine Jan, 2012 | Pubmed ID: 28058187
CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice.
Scientific reports 06, 2017 | Pubmed ID: 28646206
CD34-negative hematopoietic stem cells show distinct expression profiles of homing molecules that limit engraftment in mice and sheep.
International journal of hematology Nov, 2017 | Pubmed ID: 28687990
Variation in the Incidence of Teratomas after the Transplantation of Nonhuman Primate ES Cells into Immunodeficient Mice.
Cell transplantation Sep, 2008 | Pubmed ID: 28863750
Swine used in the medical university: overview of 20 years of experience.
Experimental animals Feb, 2018 | Pubmed ID: 28993564
Production and rearing of germ-free X-SCID pigs.
Experimental animals May, 2018 | Pubmed ID: 29162766
Modeling lethal X-linked genetic disorders in pigs with ensured fertility.
Proceedings of the National Academy of Sciences of the United States of America 01, 2018 | Pubmed ID: 29311328
Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells.
Oncotarget Jan, 2018 | Pubmed ID: 29464084
Generation of novel Il2rg-knockout mice with Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and Cas9.
Experimental animals Dec, 2019 | Pubmed ID: 31801915
A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation.
Scientific reports Mar, 2020 | Pubmed ID: 32144297
Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells.
Experimental hematology Jan, 2021 | Pubmed ID: 33395577
Non-viral genome-editing in mouse bona fide hematopoietic stem cells with CRISPR/Cas9.
Molecular therapy. Methods & clinical development Mar, 2021 | Pubmed ID: 33614821
Razan E. Ahmed*,1,
Nawin Chanthra*,1,
Tatsuya Anzai1,2,
Keiichiro Koiwai3,4,
Tomoki Murakami4,
Hiroaki Suzuki4,
Yutaka Hanazono1,
Hideki Uosaki1
1Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University,
2Department of Pediatrics, Jichi Medical University,
3Institute of Global Innovation Research, Tokyo University of Agriculture and Technology,
4Department of Precision Mechanics, Faculty of Science and Engineering, Chuo University
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