Maura Dandri

Morphological and functional analysis of rat hepatocyte spheroids generated on poly(L-lactic acid) polymer in a pulsatile flow bioreactor.

In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.

RGB marking facilitates multicolor clonal cell tracking.

Chimeric mouse model of hepatitis B virus infection.

New insight in the pathobiology of hepatitis B virus infection.

Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.

Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.

Experimental models and therapeutic approaches for HBV.

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus.

Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection.

Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration.

Multiplexing clonality: combining RGB marking and genetic barcoding.

Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

Mouse models of hepatitis B and delta virus infection.

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism.

Matrix conditions and KLF2-dependent induction of heme oxygenase-1 modulate inhibition of HCV replication by fluvastatin.

Relevance of a full-length genomic RNA standard and a thermal-shock step for optimal hepatitis delta virus quantification.

Combined glucocorticoid and antiviral therapy of hepatitis B virus-related liver failure.

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection.

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.

Latest developments in the treatment of hepatitis B.

Hepatitis B and Delta Virus: Advances on Studies about Interactions between the Two Viruses and the Infected Hepatocyte.

The challenge of protecting without overprotecting: The two sides of myeloid-derived suppressor cells in hepatitis B viral infection.

Variability in long-term hepatitis B virus dynamics under antiviral therapy.

Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation.

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer.

Experimental in vitro and in vivo models for the study of human hepatitis B virus infection.

Mechanism of Hepatitis B Virus Persistence in Hepatocytes and Its Carcinogenic Potential.

Serum HBV pgRNA as a clinical marker for cccDNA activity.

Immunofluorescent Staining for the Detection of the Hepatitis B Core Antigen in Frozen Liver Sections of Human Liver Chimeric Mice.

Haem oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice.

Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo.

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.

Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice.

The Role of cccDNA in HBV Maintenance.

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection.

Animal models of HBV infection.

A novel orally available small molecule that inhibits hepatitis B virus expression.

Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection.

Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo.

Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3.

Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture.

Comparative Analysis of the Antiviral Effects Mediated by Type I and III Interferons in Hepatitis B Virus-Infected Hepatocytes.

A global scientific strategy to cure hepatitis B.

T cell receptor grafting allows virological control of Hepatitis B virus infection.

Down-regulation of cell membrane localized NTCP expression in proliferating hepatocytes prevents hepatitis B virus infection.

CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans.

Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes.

Epigenetic modulation in chronic hepatitis B virus infection.

A novel method to precisely quantify hepatitis B virus covalently closed circular (ccc)DNA formation and maintenance.

Murine hepatocytes do not support persistence of Hepatitis D virus mono-infection in vivo.

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series.

cccDNA Maintenance in Chronic Hepatitis B - Targeting the Matrix of Viral Replication.

Hepatitis Delta Virus Acts as an Immunogenic Adjuvant in Hepatitis B Virus-Infected Hepatocytes.

Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo.