Michael A. Hough

Response to copper stress in Streptomyces lividans extends beyond genes under direct control of a copper-sensitive operon repressor protein (CsoR).

The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant.

Structural and mechanistic insights into an extracytoplasmic copper trafficking pathway in Streptomyces lividans.

The benefit of the European User Community from transnational access to national radiation facilities.

Fingerprinting redox and ligand states in haemprotein crystal structures using resonance Raman spectroscopy.

The structure of a class 3 nonsymbiotic plant haemoglobin from Arabidopsis thaliana reveals a novel N-terminal helical extension.

NO binding to the proapoptotic cytochrome c-cardiolipin complex.

Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data.

Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells.

Conformational control of the binding of diatomic gases to cytochrome c'.

Resonance Raman Spectra of Five-Coordinate Heme-Nitrosyl Cytochromes c': Effect of the Proximal Heme-NO Environment.

GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of Streptomyces lividans.

Structural insights into conformational switching in the copper metalloregulator CsoR from Streptomyces lividans.

Cytochromes c': Structure, Reactivity and Relevance to Haem-Based Gas Sensing.

Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases.

Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal.

Active-site maturation and activity of the copper-radical oxidase GlxA are governed by a tryptophan residue.

Interaction of Azole-Based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: A Molecular Basis for Toxicity.

Engineering proximal distal heme-NO coordination dinitrosyl dynamics: implications for NO sensor design.

Photoreduction and validation of haem-ligand intermediate states in protein crystals by single-crystal spectroscopy and diffraction.

Choosing the optimal spectroscopic toolkit to understand protein function.

Recent structural insights into the function of copper nitrite reductases.

Active-site protein dynamics and solvent accessibility in native copper nitrite reductase.

Distinguishing Nitro vs Nitrito Coordination in Cytochrome c' Using Vibrational Spectroscopy and Density Functional Theory.

Heightened Dynamics of the Oxidized Y48H Variant of Human Cytochrome c Increases Its Peroxidatic Activity.

A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans.

From crystal to structure with CCP4.

Enzyme catalysis captured using multiple structures from one crystal at varying temperatures.

A QM/MM Study of Nitrite Binding Modes in a Three-Domain Heme-Cu Nitrite Reductase.

Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.

An Aromatic Dyad Motif in Dye Decolourising Peroxidases Has Implications for Free Radical Formation and Catalysis.

One fold, two functions: cytochrome P460 and cytochrome '-β from the methanotroph (Bath).

Correction: One fold, two functions: cytochrome P460 and cytochrome c'-β from the methanotroph (Bath).

A Histidine Residue and a Tetranuclear Cuprous-thiolate Cluster Dominate the Copper Loading Landscape of a Copper Storage Protein from Streptomyces lividans.

Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins.

High-throughput structures of protein-ligand complexes at room temperature using serial femtosecond crystallography.

Successful sample preparation for serial crystallography experiments.

A subtle structural change in the distal haem pocket has a remarkable effect on tuning hydrogen peroxide reactivity in dye decolourising peroxidases from Streptomyces lividans.

Correction: One fold, two functions: cytochrome P460 and cytochrome c'-β from the methanotroph (Bath).

Serial Femtosecond Zero Dose Crystallography Captures a Water-Free Distal Heme Site in a Dye-Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in Fe =O Formation.

Hydroxylamine Complexes of Cytochrome : Influence of Heme Iron Redox State on Kinetic and Spectroscopic Properties.