Luke Alphey

Dominant lethality and insect population control.

PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster.

Re-engineering the sterile insect technique.

Functional interaction between nuclear inhibitor of protein phosphatase type 1 (NIPP1) and protein phosphatase type 1 (PP1) in Drosophila: consequences of over-expression of NIPP1 in flies and suppression by co-expression of PP1.

Malaria control with genetically manipulated insect vectors.

Trithorax interacts with type 1 serine/threonine protein phosphatase in Drosophila.

Ectopic expression of inhibitors of protein phosphatase type 1 (PP1) can be used to analyze roles of PP1 in Drosophila development.

giant nuclei is essential in the cell cycle transition from meiosis to mitosis.

Genetic control of vector populations: an imminent prospect.

Cloning and expression of mars, a novel member of the guanylate kinase associated protein family in Drosophila.

The essential role of PP1beta in Drosophila is to regulate nonmuscle myosin.

PP1beta9C interacts with Trithorax in Drosophila wing development.

A dominant lethal genetic system for autocidal control of the Mediterranean fruitfly.

Bifocal and PP1 interaction regulates targeting of the R-cell growth cone in Drosophila.

Germ line specific expression of a protein phosphatase Y interacting protein (PPYR1) in Drosophila.

Mosquito transgenesis: what is the fitness cost?

CG15031/PPYR1 is an intrinsically unstructured protein that interacts with protein phosphatase Y.

Transposon-free insertions for insect genetic engineering.

Towards a comprehensive analysis of the protein phosphatase 1 interactome in Drosophila.

Yeast two-hybrid screens to identify Drosophila PP1-binding proteins.

The nonmuscle myosin phosphatase PP1beta (flapwing) negatively regulates Jun N-terminal kinase in wing imaginal discs of Drosophila.

Female-specific insect lethality engineered using alternative splicing.

Late-acting dominant lethal genetic systems and mosquito control.

Essential, overlapping and redundant roles of the Drosophila protein phosphatase 1 alpha and 1 beta genes.

Analyzing the control of mosquito-borne diseases by a dominant lethal genetic system.

Genetic sexing through the use of Y-linked transgenes.

Managing insecticide resistance by mass release of engineered insects.

Drosophila Uri, a PP1alpha binding protein, is essential for viability, maintenance of DNA integrity and normal transcriptional activity.

Insect population suppression using engineered insects.

Interview with Luke Alphey, Ph.D. [Interview by Vicki Glaser].

Natural and engineered mosquito immunity.

Combining pest control and resistance management: synergy of engineered insects with Bt crops.

Sterile-insect methods for control of mosquito-borne diseases: an analysis.

Sex separation strategies: past experience and new approaches.

Female-specific flightless phenotype for mosquito control.

Transcriptomics and disease vector control.

piggybac- and PhiC31-mediated genetic transformation of the Asian tiger mosquito, Aedes albopictus (Skuse).

Use of a regulatory mechanism of sex determination in pest insect control.

Modeling resistance to genetic control of insects.

Irritant and repellent behavioral responses of Aedes aegypti male populations developed for RIDL disease control strategies.

Genetic elimination of dengue vector mosquitoes.

Why RIDL is not SIT.

Comparison of life history characteristics of the genetically modified OX513A line and a wild type strain of Aedes aegypti.

Field performance of a genetically engineered strain of pink bollworm.

A model framework to estimate impact and cost of genetics-based sterile insect methods for dengue vector control.

Cost of mating and insemination capacity of a genetically modified mosquito Aedes aegypti OX513A compared to its wild type counterpart.

Field performance of engineered male mosquitoes.

Multiplex detection and SNP genotyping in a single fluorescence channel.

Appropriate regulation of GM insects.

DengueTools: innovative tools and strategies for the surveillance and control of dengue.

Field longevity of a fluorescent protein marker in an engineered strain of the pink bollworm, Pectinophora gossypiella (Saunders).

Mating compatibility and competitiveness of transgenic and wild type Aedes aegypti (L.) under contained semi-field conditions.

Control of the olive fruit fly using genetics-enhanced sterile insect technique.

Female-specific flightless (fsRIDL) phenotype for control of Aedes albopictus.

Flight performance and teneral energy reserves of two genetically-modified and one wild-type strain of the yellow fever mosquito Aedes aegypti.

Successful suppression of a field mosquito population by sustained release of engineered male mosquitoes.

Open field release of genetically engineered sterile male Aedes aegypti in Malaysia.

Engineered repressible lethality for controlling the pink bollworm, a lepidopteran pest of cotton.

Field cage studies and progressive evaluation of genetically-engineered mosquitoes.

Polymerase chain displacement reaction.

The orthologue of the fruitfly sex behaviour gene fruitless in the mosquito Aedes aegypti: evolution of genomic organisation and alternative splicing.

Oral ingestion of transgenic RIDL Ae. aegypti larvae has no negative effect on two predator Toxorhynchites species.

Transgene-based, female-specific lethality system for genetic sexing of the silkworm, Bombyx mori.

Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi.

Fitness of transgenic mosquito Aedes aegypti males carrying a dominant lethal genetic system.

Engineered female-specific lethality for control of pest Lepidoptera.

Genetic control of Aedes mosquitoes.

DsRed2 transient expression in Culex quinquefasciatus mosquitoes.

Genetic Control of Mosquitoes.

PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth.