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Dominant lethality and insect population control.
Molecular and biochemical parasitology May, 2002 | Pubmed ID: 12034450
PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster.
Nature genetics Aug, 2002 | Pubmed ID: 12134149
Re-engineering the sterile insect technique.
Insect biochemistry and molecular biology Oct, 2002 | Pubmed ID: 12225915
Functional interaction between nuclear inhibitor of protein phosphatase type 1 (NIPP1) and protein phosphatase type 1 (PP1) in Drosophila: consequences of over-expression of NIPP1 in flies and suppression by co-expression of PP1.
The Biochemical journal Dec, 2002 | Pubmed ID: 12358598
Malaria control with genetically manipulated insect vectors.
Science (New York, N.Y.) Oct, 2002 | Pubmed ID: 12364786
Trithorax interacts with type 1 serine/threonine protein phosphatase in Drosophila.
EMBO reports Jan, 2003 | Pubmed ID: 12524522
Ectopic expression of inhibitors of protein phosphatase type 1 (PP1) can be used to analyze roles of PP1 in Drosophila development.
Genetics May, 2003 | Pubmed ID: 12750335
giant nuclei is essential in the cell cycle transition from meiosis to mitosis.
Development (Cambridge, England) Jul, 2003 | Pubmed ID: 12756181
Genetic control of vector populations: an imminent prospect.
Tropical medicine & international health : TM & IH Apr, 2004 | Pubmed ID: 15078260
Cloning and expression of mars, a novel member of the guanylate kinase associated protein family in Drosophila.
Gene expression patterns : GEP Sep, 2004 | Pubmed ID: 15261830
The essential role of PP1beta in Drosophila is to regulate nonmuscle myosin.
Molecular biology of the cell Oct, 2004 | Pubmed ID: 15269282
PP1beta9C interacts with Trithorax in Drosophila wing development.
Developmental dynamics : an official publication of the American Association of Anatomists Oct, 2004 | Pubmed ID: 15366010
A dominant lethal genetic system for autocidal control of the Mediterranean fruitfly.
Nature biotechnology Apr, 2005 | Pubmed ID: 15750586
Bifocal and PP1 interaction regulates targeting of the R-cell growth cone in Drosophila.
Developmental biology Dec, 2005 | Pubmed ID: 16280124
Germ line specific expression of a protein phosphatase Y interacting protein (PPYR1) in Drosophila.
Gene expression patterns : GEP Oct, 2006 | Pubmed ID: 16530491
Mosquito transgenesis: what is the fitness cost?
Trends in parasitology May, 2006 | Pubmed ID: 16564223
CG15031/PPYR1 is an intrinsically unstructured protein that interacts with protein phosphatase Y.
Archives of biochemistry and biophysics Jul, 2006 | Pubmed ID: 16631104
Transposon-free insertions for insect genetic engineering.
Nature biotechnology Jul, 2006 | Pubmed ID: 16823373
Towards a comprehensive analysis of the protein phosphatase 1 interactome in Drosophila.
Journal of molecular biology Nov, 2006 | Pubmed ID: 17007873
Yeast two-hybrid screens to identify Drosophila PP1-binding proteins.
Methods in molecular biology (Clifton, N.J.) , 2007 | Pubmed ID: 17200561
The nonmuscle myosin phosphatase PP1beta (flapwing) negatively regulates Jun N-terminal kinase in wing imaginal discs of Drosophila.
Genetics Apr, 2007 | Pubmed ID: 17277363
Female-specific insect lethality engineered using alternative splicing.
Nature biotechnology Mar, 2007 | Pubmed ID: 17322873
Late-acting dominant lethal genetic systems and mosquito control.
BMC biology , 2007 | Pubmed ID: 17374148
Essential, overlapping and redundant roles of the Drosophila protein phosphatase 1 alpha and 1 beta genes.
Genetics May, 2007 | Pubmed ID: 17513890
Analyzing the control of mosquito-borne diseases by a dominant lethal genetic system.
Proceedings of the National Academy of Sciences of the United States of America May, 2007 | Pubmed ID: 17519336
Genetic sexing through the use of Y-linked transgenes.
Insect biochemistry and molecular biology Nov, 2007 | Pubmed ID: 17916503
Managing insecticide resistance by mass release of engineered insects.
Journal of economic entomology Oct, 2007 | Pubmed ID: 17972643
Drosophila Uri, a PP1alpha binding protein, is essential for viability, maintenance of DNA integrity and normal transcriptional activity.
BMC molecular biology , 2008 | Pubmed ID: 18412953
Insect population suppression using engineered insects.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 18510017
Interview with Luke Alphey, Ph.D. [Interview by Vicki Glaser].
Vector borne and zoonotic diseases (Larchmont, N.Y.) Apr, 2009 | Pubmed ID: 19371156
Natural and engineered mosquito immunity.
Journal of biology , 2009 | Pubmed ID: 19439051
Combining pest control and resistance management: synergy of engineered insects with Bt crops.
Journal of economic entomology Apr, 2009 | Pubmed ID: 19449654
Sterile-insect methods for control of mosquito-borne diseases: an analysis.
Vector borne and zoonotic diseases (Larchmont, N.Y.) Apr, 2010 | Pubmed ID: 19725763
Sex separation strategies: past experience and new approaches.
Malaria journal , 2009 | Pubmed ID: 19917075
Female-specific flightless phenotype for mosquito control.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20176967
Transcriptomics and disease vector control.
BMC biology , 2010 | Pubmed ID: 20525113
piggybac- and PhiC31-mediated genetic transformation of the Asian tiger mosquito, Aedes albopictus (Skuse).
PLoS neglected tropical diseases , 2010 | Pubmed ID: 20808959
Use of a regulatory mechanism of sex determination in pest insect control.
Journal of genetics Sep, 2010 | Pubmed ID: 20876996
Modeling resistance to genetic control of insects.
Journal of theoretical biology Feb, 2011 | Pubmed ID: 21075122
Irritant and repellent behavioral responses of Aedes aegypti male populations developed for RIDL disease control strategies.
Journal of medical entomology Nov, 2010 | Pubmed ID: 21175058
Genetic elimination of dengue vector mosquitoes.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2011 | Pubmed ID: 21383140
Why RIDL is not SIT.
Trends in parasitology Aug, 2011 | Pubmed ID: 21659002
Comparison of life history characteristics of the genetically modified OX513A line and a wild type strain of Aedes aegypti.
PloS one , 2011 | Pubmed ID: 21698096
Field performance of a genetically engineered strain of pink bollworm.
PloS one , 2011 | Pubmed ID: 21931649
A model framework to estimate impact and cost of genetics-based sterile insect methods for dengue vector control.
PloS one , 2011 | Pubmed ID: 21998654
Cost of mating and insemination capacity of a genetically modified mosquito Aedes aegypti OX513A compared to its wild type counterpart.
PloS one , 2011 | Pubmed ID: 22022518
Field performance of engineered male mosquitoes.
Nature biotechnology Nov, 2011 | Pubmed ID: 22037376
Multiplex detection and SNP genotyping in a single fluorescence channel.
PloS one , 2012 | Pubmed ID: 22272339
Appropriate regulation of GM insects.
PLoS neglected tropical diseases Jan, 2012 | Pubmed ID: 22303495
DengueTools: innovative tools and strategies for the surveillance and control of dengue.
Global health action , 2012 | Pubmed ID: 22451836
Field longevity of a fluorescent protein marker in an engineered strain of the pink bollworm, Pectinophora gossypiella (Saunders).
PloS one , 2012 | Pubmed ID: 22693645
Mating compatibility and competitiveness of transgenic and wild type Aedes aegypti (L.) under contained semi-field conditions.
Transgenic research Feb, 2013 | Pubmed ID: 22700207
Control of the olive fruit fly using genetics-enhanced sterile insect technique.
BMC biology , 2012 | Pubmed ID: 22713628
Female-specific flightless (fsRIDL) phenotype for control of Aedes albopictus.
PLoS neglected tropical diseases , 2012 | Pubmed ID: 22802980
Flight performance and teneral energy reserves of two genetically-modified and one wild-type strain of the yellow fever mosquito Aedes aegypti.
Vector borne and zoonotic diseases (Larchmont, N.Y.) Dec, 2012 | Pubmed ID: 22835152
Successful suppression of a field mosquito population by sustained release of engineered male mosquitoes.
Nature biotechnology Sep, 2012 | Pubmed ID: 22965050
Open field release of genetically engineered sterile male Aedes aegypti in Malaysia.
PloS one , 2012 | Pubmed ID: 22970102
Engineered repressible lethality for controlling the pink bollworm, a lepidopteran pest of cotton.
PloS one , 2012 | Pubmed ID: 23226548
Field cage studies and progressive evaluation of genetically-engineered mosquitoes.
PLoS neglected tropical diseases , 2013 | Pubmed ID: 23350003
Polymerase chain displacement reaction.
BioTechniques Feb, 2013 | Pubmed ID: 23384180
The orthologue of the fruitfly sex behaviour gene fruitless in the mosquito Aedes aegypti: evolution of genomic organisation and alternative splicing.
PloS one , 2013 | Pubmed ID: 23418412
Oral ingestion of transgenic RIDL Ae. aegypti larvae has no negative effect on two predator Toxorhynchites species.
PloS one , 2013 | Pubmed ID: 23527029
Transgene-based, female-specific lethality system for genetic sexing of the silkworm, Bombyx mori.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23569267
Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi.
Malaria journal , 2013 | Pubmed ID: 23622561
Fitness of transgenic mosquito Aedes aegypti males carrying a dominant lethal genetic system.
PloS one , 2013 | Pubmed ID: 23690948
Engineered female-specific lethality for control of pest Lepidoptera.
ACS synthetic biology Mar, 2013 | Pubmed ID: 23802263
Genetic control of Aedes mosquitoes.
Pathogens and global health Jun, 2013 | Pubmed ID: 23816508
DsRed2 transient expression in Culex quinquefasciatus mosquitoes.
Memórias do Instituto Oswaldo Cruz Jun, 2013 | Pubmed ID: 23828005
Genetic Control of Mosquitoes.
Annual review of entomology Oct, 2013 | Pubmed ID: 24160434
PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth.
PLoS genetics Oct, 2013 | Pubmed ID: 24204300
Danilo O. Carvalho1,2,
Derric Nimmo1,
Neil Naish1,
Andrew R. McKemey1,
Pam Gray1,
André B. B. Wilke3,
Mauro T. Marrelli3,
Jair F. Virginio4,
Luke Alphey1,5,
Margareth L. Capurro2,6
1, Oxitec Ltd,
2Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo,
3Departamento de Epidemiologia, Universidade de São Paulo,
4, Moscamed Brasil,
5Deptartment of Zoology, University of Oxford,
6, Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM)
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