Lucia Banci

NMR characterization and solution structure determination of the oxidized cytochrome c7 from Desulfuromonas acetoxidans.

Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

New Type 2 Copper-Cysteinate Proteins. Copper Site Histidine-to-Cysteine Mutants of Yeast Copper-Zinc Superoxide Dismutase.

Individual Reduction Potentials of the Iron Ions in Fe(2)S(2) and High-Potential Fe(4)S(4) Ferredoxins.

Molecular dynamics characterization of the C2 domain of protein kinase Cbeta.

Metallochaperones and metal-transporting ATPases: a comparative analysis of sequences and structures.

Direct detection of hydrogen bonds in monomeric superoxide dismutase: biological implications.

Solution structure of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis in the apo and Cu(I) loaded states.

NMR solution structure, backbone mobility, and homology modeling of c-type cytochromes from gram-positive bacteria.

Chemical shift-based constraints for solution structure determination of paramagnetic low-spin heme proteins with bis-His and His-CN axial ligands: the cases of oxidized cytochrome b(5) and Met80Ala cyano-cytochrome c.

The solution structure of reduced dimeric copper zinc superoxide dismutase. The structural effects of dimerization.

Structure and dynamics of copper-free SOD: The protein before binding copper.

Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis.

Unfolding and pH studies on manganese peroxidase: role of heme and calcium on secondary structure stability.

A new zinc-protein coordination site in intracellular metal trafficking: solution structure of the Apo and Zn(II) forms of ZntA(46-118).

Nuclear magnetic resonance spectroscopy studies on copper proteins.

Solution structure and characterization of the heme chaperone CcmE.

Molecular dynamics simulations of metalloproteins.

Dynamic properties of the G93A mutant of copper-zinc superoxide dismutase as detected by NMR spectroscopy: implications for the pathology of familial amyotrophic lateral sclerosis.

Understanding copper trafficking in bacteria: interaction between the copper transport protein CopZ and the N-terminal domain of the copper ATPase CopA from Bacillus subtilis.

X-ray absorption and NMR spectroscopic studies of CopZ, a copper chaperone in Bacillus subtilis: the coordination properties of the copper ion.

Structural genomics of proteins involved in copper homeostasis.

A redox switch in CopC: an intriguing copper trafficking protein that binds copper(I) and copper(II) at different sites.

A strategy for the NMR characterization of type II copper(II) proteins: the case of the copper trafficking protein CopC from Pseudomonas Syringae.

Superoxide dismutase folding/unfolding pathway: role of the metal ions in modulating structural and dynamical features.

A further investigation of the cytochrome b5-cytochrome c complex.

NMR study of manganese(II) binding by a new versatile peroxidase from the white-rot fungus Pleurotus eryngii.

A core mutation affecting the folding properties of a soluble domain of the ATPase protein CopA from Bacillus subtilis.

Solution structure of Apo Cu,Zn superoxide dismutase: role of metal ions in protein folding.

The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction.

Structural basis for the function of the N-terminal domain of the ATPase CopA from Bacillus subtilis.

Solution structure of Sco1: a thioredoxin-like protein Involved in cytochrome c oxidase assembly.

Solution structure of apo CopZ from Bacillus subtilis: further analysis of the changes associated with the presence of copper.

Paramagnetism-based restraints for Xplor-NIH.

Bioinformatic comparison of structures and homology-models of matrix metalloproteinases.

Solution structure and backbone dynamics of the Cu(I) and apo forms of the second metal-binding domain of the Menkes protein ATP7A.

A docking approach to the study of copper trafficking proteins; interaction between metallochaperones and soluble domains of copper ATPases.

Solution structures of a cyanobacterial metallochaperone: insight into an atypical copper-binding motif.

Solution structure of Cox11, a novel type of beta-immunoglobulin-like fold involved in CuB site formation of cytochrome c oxidase.

Modeling the backbone dynamics of reduced and oxidized solvated rat microsomal cytochrome b5.

The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status.

Integration of XAS and NMR techniques for the structure determination of metalloproteins. Examples from the study of copper transport proteins.

Backbone-only restraints for fast determination of the protein fold: the role of paramagnetism-based restraints. Cytochrome b562 as an example.

An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein.

Ortholog search of proteins involved in copper delivery to cytochrome C oxidase and functional analysis of paralogs and gene neighbors by genomic context.

A copper(I) protein possibly involved in the assembly of CuA center of bacterial cytochrome c oxidase.

Folding studies of Cox17 reveal an important interplay of cysteine oxidation and copper binding.

A prokaryotic superoxide dismutase paralog lacking two Cu ligands: from largely unstructured in solution to ordered in the crystal.

Comparative analysis of the ADAM and ADAMTS families.

An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A.

Fully metallated S134N Cu,Zn-superoxide dismutase displays abnormal mobility and intermolecular contacts in solution.

Structural interplay between calcium(II) and copper(II) binding to S100A13 protein.

A NMR study of the interaction of a three-domain construct of ATP7A with copper(I) and copper(I)-HAH1: the interplay of domains.

From an inactive prokaryotic SOD homologue to an active protein through site-directed mutagenesis.

Human SOD1 before harboring the catalytic metal: solution structure of copper-depleted, disulfide-reduced form.

Structural basis for metal binding specificity: the N-terminal cadmium binding domain of the P1-type ATPase CadA.

Counting the zinc-proteins encoded in the human genome.

Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis.

Structure of human Wilson protein domains 5 and 6 and their interplay with domain 4 and the copper chaperone HAH1 in copper uptake.

NMR structures of paramagnetic metalloproteins.

The delivery of copper for thylakoid import observed by NMR.

The Atx1-Ccc2 complex is a metal-mediated protein-protein interaction.

A hint for the function of human Sco1 from different structures.

Solution structure and intermolecular interactions of the third metal-binding domain of ATP7A, the Menkes disease protein.

Zinc through the three domains of life.

Human Sco1 functional studies and pathological implications of the P174L mutant.

Structural proteomics: from the molecule to the system.

Non-heme iron through the three domains of life.

The functions of Sco proteins from genome-based analysis.

The different intermolecular interactions of the soluble copper-binding domains of the menkes protein, ATP7A.

Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS.

NMR structural analysis of cadmium sensing by winged helix repressor CmtR.

Metalation of the amyotrophic lateral sclerosis mutant glycine 37 to arginine superoxide dismutase (SOD1) apoprotein restores its structural and dynamical properties in solution to those of metalated wild-type SOD1.

Matrix metalloproteinase-inhibitor interaction: the solution structure of the catalytic domain of human matrix metalloproteinase-3 with different inhibitors.

A structural characterization of human SCO2.

Interaction of the two soluble metal-binding domains of yeast Ccc2 with copper(I)-Atx1.

Occurrence of copper proteins through the three domains of life: a bioinformatic approach.

An idea whose time has come.

A structural-dynamical characterization of human Cox17.

SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization.

Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer.

Metal binding domains 3 and 4 of the Wilson disease protein: solution structure and interaction with the copper(I) chaperone HAH1.

Mechanism of Cu(A) assembly.

The copper-responsive repressor CopR of Lactococcus lactis is a 'winged helix' protein.

An NMR study of the interaction of the N-terminal cytoplasmic tail of the Wilson disease protein with copper(I)-HAH1.

MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria.

The coiled coil-helix-coiled coil-helix proteins may be redox proteins.

Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants.

Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces.

NMR structural analysis of the soluble domain of ZiaA-ATPase and the basis of selective interactions with copper metallochaperone Atx1.

The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.

Copper trafficking in biology: an NMR approach.

A novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding.

Cellular copper distribution: a mechanistic systems biology approach.

Molecular recognition in copper trafficking.

Affinity gradients drive copper to cellular destinations.

NMR in structural proteomics and beyond.

Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein import.

NMR characterization of a "fibril-ready" state of demetalated wild-type superoxide dismutase.

Sco proteins are involved in electron transfer processes.

Structural and functional characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain.

Molecular recognition and substrate mimicry drive the electron-transfer process between MIA40 and ALR.

Seeking the determinants of the elusive functions of Sco proteins.

Copper exposure effects on yeast mitochondrial proteome.

Anamorsin is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery.

Functional role of two interhelical disulfide bonds in human Cox17 protein from a structural perspective.

In-cell NMR in E. coli to monitor maturation steps of hSOD1.

Cyanobacterial metallochaperone inhibits deleterious side reactions of copper.

An electron-transfer path through an extended disulfide relay system: the case of the redox protein ALR.

Interaction of cisplatin with human superoxide dismutase.

Structure of nucleophosmin DNA-binding domain and analysis of its complex with a G-quadruplex sequence from the c-MYC promoter.

Structural characterization of CHCHD5 and CHCHD7: two atypical human twin CX9C proteins.

Human superoxide dismutase 1 (hSOD1) maturation through interaction with human copper chaperone for SOD1 (hCCS).

HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies.

An intrinsically disordered domain has a dual function coupled to compartment-dependent redox control.

Atomic-resolution monitoring of protein maturation in live human cells by NMR.

Metallomics and the cell: some definitions and general comments.

Molecular view of an electron transfer process essential for iron-sulfur protein biogenesis.

Mechanistic aspects of hSOD1 maturation from the solution structure of Cu(I) -loaded hCCS domain 1 and analysis of disulfide-free hSOD1 mutants.

Visualization of redox-controlled protein fold in living cells.

Human anamorsin binds [2Fe-2S] clusters with unique electronic properties.

Solid-state NMR studies of metal-free SOD1 fibrillar structures.

[2Fe-2S] cluster transfer in iron-sulfur protein biogenesis.

Biological inorganic chemists pay tribute to Ivano Bertini.

Structural insights of proteins in sub-cellular compartments: In-mitochondria NMR.

Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.

Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin.

In-cell NMR reveals potential precursor of toxic species from SOD1 fALS mutants.

Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein.

N-terminal domains mediate [2Fe-2S] cluster transfer from glutaredoxin-3 to anamorsin.

Loop recognition and copper-mediated disulfide reduction underpin metal site assembly of CuA in human cytochrome oxidase.

Protein interaction patterns in different cellular environments are revealed by in-cell NMR.

Direct structural evidence of protein redox regulation obtained by in-cell NMR.

Elucidating the Molecular Function of Human BOLA2 in GRX3-Dependent Anamorsin Maturation Pathway.

A Unique Tool for Cellular Structural Biology: In-cell NMR.

The Casein Kinase 2-Dependent Phosphorylation of NS5A Domain 3 from Hepatitis C Virus Followed by Time-Resolved NMR Spectroscopy.

Structural characterization of zinc-bound Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile.

Exploiting Bacterial Operons To Illuminate Human Iron-Sulfur Proteins.

Characterization of proteins by in-cell NMR spectroscopy in cultured mammalian cells.

MetalPredator: a web server to predict iron-sulfur cluster binding proteomes.

Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility.

Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins.

[4Fe-4S] Cluster Assembly in Mitochondria and Its Impairment by Copper.

The Relationship between Environmental Dioxygen and Iron-Sulfur Proteins Explored at the Genome Level.

In-cell NMR: a topical review.

Structural insights into the molecular function of human [2Fe-2S] BOLA1-GRX5 and [2Fe-2S] BOLA3-GRX5 complexes.

Anamorsin/Ndor1 Complex Reduces [2Fe-2S]-MitoNEET via a Transient Protein-Protein Interaction.

Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP.

Intracellular metal binding and redox behavior of human DJ-1.

Protein networks in the maturation of human iron-sulfur proteins.

A molecular chaperone activity of CCS restores the maturation of SOD1 fALS mutants.

The NMR contribution to protein-protein networking in Fe-S protein maturation.

The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.

Investigating the role of the human CIA2A-CIAO1 complex in the maturation of aconitase.

Correction to: The NMR contribution to protein-protein networking in Fe-S protein maturation.

In-Cell NMR in Human Cells: Direct Protein Expression Allows Structural Studies of Protein Folding and Maturation.

A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

The human iron-proteome.

IBA57 Recruits ISCA2 to Form a [2Fe-2S] Cluster-Mediated Complex.

The cellular economy of the Saccharomyces cerevisiae zinc proteome.

Interaction of Half Oxa-/Half -Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity.

Real-Time Insights into Biological Events: In-Cell Processes and Protein-Ligand Interactions.

Cadmium effects on superoxide dismutase 1 in human cells revealed by NMR.

A signalling cascade involving receptor-activated phospholipase A, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility.

In-house high-energy-remote SAD phasing using the magic triangle: how to tackle the P1 low symmetry using multiple orientations of the same crystal of human IBA57 to increase the multiplicity.

Paramagnetic H NMR Spectroscopy to Investigate the Catalytic Mechanism of Radical S-Adenosylmethionine Enzymes.

Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach.

A pathway for assembling [4Fe-4S] clusters in mitochondrial iron-sulfur protein biogenesis.

Structural properties of [2Fe-2S] ISCA2-IBA57: a complex of the mitochondrial iron-sulfur cluster assembly machinery.

Methylglyoxal interaction with superoxide dismutase 1.

CIAO3 protein forms a stable ternary complex with two key players of the human cytosolic iron-sulfur cluster assembly machinery.

GLRX3 Acts as a [2Fe-2S] Cluster Chaperone in the Cytosolic Iron-Sulfur Assembly Machinery Transferring [2Fe-2S] Clusters to NUBP1.

NMR quality control of fragment libraries for screening.

Real-Time Quantitative In-Cell NMR: Ligand Binding and Protein Oxidation Monitored in Human Cells Using Multivariate Curve Resolution.

West-Life: A Virtual Research Environment for structural biology.

H, C, and N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b.

H,C and N chemical shift assignments of the SUD domains of SARS-CoV-2 non-structural protein 3c: "the N-terminal domain-SUD-N".

A combined NMR and EPR investigation on the effect of the disordered RGG regions in the structure and the activity of the RRM domain of FUS.

HIV-1 Tat Protein Enters Dysfunctional Endothelial Cells via Integrins and Renders Them Permissive to Virus Replication.

H,C and N chemical shift assignments of the SUD domains of SARS-CoV-2 non-structural protein 3c: "The SUD-M and SUD-C domains".

New structural and functional insights from in-cell NMR.

Protein in-cell NMR spectroscopy at 1.2 GHz.

ISCA1 Orchestrates ISCA2 and NFU1 in the Maturation of Human Mitochondrial [4Fe-4S] Proteins.

In Cellulo Mössbauer and EPR Studies Bring New Evidence to the Long-Standing Debate on Iron-Sulfur Cluster Binding in Human Anamorsin.

Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 2 Caused by CYS59TYR BOLA3 Mutation.

Rapid protein delivery to living cells for biomolecular investigation.

SARS-CoV-2 M inhibition by a zinc ion: structural features and hints for drug design.