Department of Molecular Genetics,
The Donnelly Centre for Cellular and Biomolecular Research,
Department of Pharmacology and Toxicology
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The forkhead transcription factor UNC-130 is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor in C. elegans.
Genes & development Oct, 2000 | Pubmed ID: 11018016
Muscle arm development in Caenorhabditis elegans.
Development (Cambridge, England) Jul, 2005 | Pubmed ID: 15930100
Network news: functional modules revealed during early embryogenesis in C. elegans.
Developmental cell Sep, 2005 | Pubmed ID: 16139218
FGF negatively regulates muscle membrane extension in Caenorhabditis elegans.
Development (Cambridge, England) Apr, 2006 | Pubmed ID: 16495308
A small-molecule screen in C. elegans yields a new calcium channel antagonist.
Nature May, 2006 | Pubmed ID: 16672971
High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans.
Nature protocols , 2006 | Pubmed ID: 17487175
Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system.
Genome biology , 2007 | Pubmed ID: 17612406
A global analysis of genetic interactions in Caenorhabditis elegans.
Journal of biology , 2007 | Pubmed ID: 17897480
Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.
PLoS genetics Feb, 2008 | Pubmed ID: 18454192
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans.
Nature chemical biology Jul, 2010 | Pubmed ID: 20512140
MADD-2, a homolog of the Opitz syndrome protein MID1, regulates guidance to the midline through UNC-40 in Caenorhabditis elegans.
Developmental cell Jun, 2010 | Pubmed ID: 20627078
MADD-4 is a secreted cue required for midline-oriented guidance in Caenorhabditis elegans.
Developmental cell Oct, 2011 | Pubmed ID: 22014523
Compound prioritization methods increase rates of chemical probe discovery in model organisms.
Chemistry & biology Oct, 2011 | Pubmed ID: 22035796
Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans.
Nature chemical biology Dec, 2011 | Pubmed ID: 22057127
Orthosteric and allosteric drug binding sites in the Caenorhabditis elegans mgl-2 metabotropic glutamate receptor.
Neuropharmacology Sep, 2012 | Pubmed ID: 22652059
EVA-1 functions as an UNC-40 Co-receptor to enhance attraction to the MADD-4 guidance cue in Caenorhabditis elegans.
PLoS genetics Aug, 2014 | Pubmed ID: 25122090
Caenorhabditis elegans is a useful model for anthelmintic discovery.
Nature communications Jun, 2015 | Pubmed ID: 26108372
The MADD-3 LAMMER Kinase Interacts with a p38 MAP Kinase Pathway to Regulate the Display of the EVA-1 Guidance Receptor in Caenorhabditis elegans.
PLoS genetics 04, 2016 | Pubmed ID: 27123983
The novel nematicide wact-86 interacts with aldicarb to kill nematodes.
PLoS neglected tropical diseases 04, 2017 | Pubmed ID: 28379972
The marginal cells of the Caenorhabditis elegans pharynx scavenge cholesterol and other hydrophobic small molecules.
Nature communications 09, 2019 | Pubmed ID: 31477732
Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery.
Nature communications 07, 2020 | Pubmed ID: 32709866
A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics.
Scientific reports 04, 2021 | Pubmed ID: 33911106
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