Rajat Varma

The immunological synapse balances T cell receptor signaling and degradation.

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins.

Nanoscale organization of multiple GPI-anchored proteins in living cell membranes.

A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.

T cell-dendritic cell immunological synapses.

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.

Necrotizing fasciitis: delay in diagnosis results in loss of limb.

Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse.

Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes.

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.

Safety and efficacy of subcutaneously administered efalizumab in adults with moderate-to-severe hand and foot psoriasis: an open-label study.

Supported planar bilayers for study of the immunological synapse.

TCR triggering by the pMHC complex: valency, affinity, and dynamics.

Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.

The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.

Diffusion and signaling revisited.

Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain.

A new fractionation assay, based on the size of formaldehyde-crosslinked, mildly sheared chromatin, delineates the chromatin structure at promoter regions.

Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster.

Immunological synapse: a multi-protein signalling cellular apparatus for controlling gene expression.

Naftifine, a topical allylamine.

On the issue of peptide recognition in T cell development.