Toshimasa Yamauchi

Determination of endogenous levels of retinoic acid isomers in type II diabetes mellitus patients. Possible correlation with HbA1c values.

Sex differences in the pharmacokinetics of pioglitazone in rats.

Adiponectin: an adipokine linking adipocytes and type 2 diabetes in humans.

Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation.

[Pathogenesis of metabolic syndrome].

Selective purification and characterization of adiponectin multimer species from human plasma.

Reduced adiponectin level is associated with severity of coronary artery disease.

Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.

[Roles of adipocytokines in the development of atherosclerosis].

[Glucose intolerance -- diabetes].

[Anti-metabolic syndrome effects of candesartan].

Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.

[Recent advances in PPARgamma research].

[Regulation of differentiation and hypertrophy of adipocytes and adipokine network by PPARgamma].

[PPARgamma antagonist as a potential drug for the treatment of obesity and diabetes].

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.

[Incretin related drugs].

Adiponectin receptor signaling: a new layer to the current model.

Crystal structure of the Ca²⁺/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609.

[Adipocytes and bone metabolism].

[Dysregulation of adipocytokines expression in metabolic syndrome].

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.

Expression levels of adiponectin receptors are decreased in human endometrial adenocarcinoma tissues.

[Pathophysiological roles of adipocytokines in the development of insulin resistance].

[Functional food component--osmotin].

The epigenome and its role in diabetes.

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.

Adiponectin receptor as a key player in healthy longevity and obesity-related diseases.

[New drug targets for the metabolic syndrome and obesity].

Genome-wide association study identifies three novel loci for type 2 diabetes.

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.

Adiponectin receptors: a review of their structure, function and how they work.

Lung abscess without sepsis in a patient with diabetes with refractory episodes of spontaneous hypoglycemia: a case report and review of the literature.

Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.

Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2.

Crystal structures of the human adiponectin receptors.

A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice.

Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity.

Association between self-stigma and self-care behaviors in patients with type 2 diabetes: a cross-sectional study.

[Adiponectin receptor-targeted therapy for lifestyle-related diseases].

[Epigenetics and Life-style diseases].

Shear Stress-Normal Stress (Pressure) Ratio Decides Forming Callus in Patients with Diabetic Neuropathy.

Willingness of patients with diabetes to use an ICT-based self-management tool: a cross-sectional study.

Psychological and behavioural patterns of stigma among patients with type 2 diabetes: a cross-sectional study.

[Aging and homeostasis. Development of novel AdipoR-targeted drugs with exercise-mimicking and anti-aging properties.].

Adiponectin/adiponectin receptor in disease and aging.

CDK5 Regulatory Subunit-Associated Protein 1-like 1 Negatively Regulates Adipocyte Differentiation through Activation of Wnt Signaling Pathway.

NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program.

Development of an Automatic Puncturing and Sampling System for a Self-Monitoring Blood Glucose Device.

[Developing Exercise-mimicking Drugs toward Realization of Preemptive Medicine for Lifestyle-related Diseases.].

Weekly Versus Daily Dipeptidyl Peptidase 4 Inhibitor Therapy for Type 2 Diabetes: Systematic Review and Meta-analysis.

Structure and function analysis of adiponectin receptors toward development of novel antidiabetic agents promoting healthy longevity.

Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity.

A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes.

Thermographic findings in a case of type 2 diabetes with foot ulcer due to callus deterioration.

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.

NAD supplementation rejuvenates aged gut adult stem cells.

Variation in process quality measures of diabetes care by region and institution in Japan during 2015-2016: An observational study of nationwide claims data.

Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34 cells using the auto-erasable Sendai virus vector.

The association between health literacy levels and patient-reported outcomes in Japanese type 2 diabetic patients.

Adiponectin/AdipoR Research and Its Implications for Lifestyle-Related Diseases.

Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity.

Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice.

A closer inspection of diabetes-related stigma: why more research is needed.

LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover.

Clinical Features of Type B Insulin Resistance in Japanese Patients: Case Report and Survey-Based Case Series Study.

How self-stigma affects patient activation in persons with type 2 diabetes: a cross-sectional study.

Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.

Identification of type 2 diabetes loci in 433,540 East Asian individuals.

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.

Pseudo-hyperglucagonemia was observed in pancreatectomized patients when measured by glucagon sandwich enzyme-linked immunosorbent assay.

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer.

Association between tear and blood glucose concentrations: Random intercept model adjusted with confounders in tear samples negative for occult blood.

Skin characteristics associated with foot callus in people with diabetes: A cross-sectional study focused on desmocollin1 in corneocytes.

Understanding the experiences of long-term maintenance of self-worth in persons with type 2 diabetes in Japan: a qualitative study.

Human adiponectin receptor AdipoR1 assumes closed and open structures.

Medical nutrition therapy and dietary counseling for patients with diabetes-energy, carbohydrates, protein intake and dietary counseling.

Oxidized albumin in blood reflects the severity of multiple vascular complications in diabetes mellitus.

Factors Associated with Callus Formation in the Plantar Region through Gait Measurement in Patients with Diabetic Neuropathy: An Observational Case-Control Study.

Clinical usefulness of multigene screening with phenotype-driven bioinformatics analysis for the diagnosis of patients with monogenic diabetes or severe insulin resistance.

NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation.

Perceptions, attitudes and barriers to obesity management: Japanese data from the ACTION-IO study.

Using mHealth to Provide Mobile App Users With Visualization of Health Checkup Data and Educational Videos on Lifestyle-Related Diseases: Methodological Framework for Content Development.

Blood Glucose Control Strategy for Type 2 Diabetes Patients With COVID-19.

eHealth Delivery of Educational Content Using Selected Visual Methods to Improve Health Literacy on Lifestyle-Related Diseases: Literature Review.

AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice.

Preparation and culture of bone marrow-derived macrophages from mice for functional analysis.

Association between nutritional guidance or ophthalmological examination and discontinuation of physician visits in patients with newly diagnosed diabetes: A retrospective cohort study using a nationwide database.

Body-weight-independent glucose-lowering effect of the β3-adrenergic receptor agonist mirabegron in humans.

Potassium Concentration in Initial Fluid Therapy and In-Hospital Mortality of Patients with Diabetic Ketoacidosis.

Prevention of diabetic foot ulcers using a smartphone and mobile thermography: a case study.

Genome-wide association studies identify two novel loci conferring susceptibility to diabetic retinopathy in Japanese patients with type 2 diabetes.

Role of Insulin Resistance in MAFLD.

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone-Releasing Hormone in the Hypothalamus.

Factors Associated with the Local Increase of Skin Temperature, 'Hotspot,' of Callus in Diabetic Foot: A Cross-Sectional Study.

Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants.

Factors associated with long-term care certification in older adults: a cross-sectional study based on a nationally representative survey in Japan.

Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes.

Retrospective nationwide study on the trends in first-line antidiabetic medication for patients with type 2 diabetes in Japan.

Clinical Characteristics and Incidences of Benign and Malignant Insulinoma Using a National Inpatient Database in Japan.

Adaptive Response as a Potential Key Link Between SGLT2 Inhibition and Renoprotection.

Chronic Intestinal Pseudo-obstruction with Mitochondrial Diseases.

Efficacy of the Self-management Support System DialBetesPlus for Diabetic Kidney Disease: Protocol for a Randomized Controlled Trial.

Effect of Branched-Chain Amino Acid Infusion on In-Hospital Mortality of Patients With Hepatic Encephalopathy and End-Stage Kidney Disease: A Retrospective Cohort Study Using a National Inpatient Database.

Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth.

Elucidating exercise-induced skeletal muscle signaling pathways and applying relevant findings to preemptive therapy for lifestyle-related diseases.

A cross-population atlas of genetic associations for 220 human phenotypes.

Effect of Digital Health Among People With Type 2 Diabetes Mellitus During the COVID-19 Pandemic in Japan.

Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity.

Risk Classification for Metabolic Syndrome and the Incidence of Cardiovascular Disease in Japan With Low Prevalence of Obesity: A Pooled Analysis of 10 Prospective Cohort Studies.

Correction to: Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity.

Correction to: Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity.

Risk for Proteinuria in Newly Defined Hypertensive People Based on the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline.

Addressing screams for evidence on renoprotection by GLP-1 receptor agonists.

New classification and diagnostic criteria for insulin resistance syndrome.

Change in Cardiovascular Health Metrics and Risk for Proteinuria Development: Analysis of a Nationwide Population-Based Database.

Impact of Glucose Tolerance and Its Change on Incident Proteinuria: Analysis of a Nationwide Population-Based Dataset.

Effect of Information and Communication Technology-Based Self-management System DialBeticsLite on Treating Abdominal Obesity in the Specific Health Guidance in Japan: Randomized Controlled Trial.

Association between proteinuria and incident colorectal cancer: analysis of a nationwide population-based database.

Associations between diabetes duration and self-stigma development in Japanese people with type 2 diabetes: a secondary analysis of cross-sectional data.

A Machine Learning-Based Predictive Model to Identify Patients Who Failed to Attend a Follow-up Visit for Diabetes Care After Recommendations From a National Screening Program.

Prediabetes in Young Adults and Its Association With Cardiovascular Health Metrics in the Progression to Diabetes.

New classification and diagnostic criteria for insulin resistance syndrome.

Impact of COVID-19 pandemic on healthcare service use for non-COVID-19 patients in Japan: retrospective cohort study.

Severe aortic stenosis during leptin replacement therapy in a patient with generalized lipodystrophy-associated progeroid syndrome due to an LMNA variant: A case report.

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.

The sodium-glucose co-transporter 2 inhibitor tofogliflozin suppresses atherosclerosis through glucose lowering in ApoE-deficient mice with streptozotocin-induced diabetes.

Evaluation of foot ulcer incidence in diabetic patients at a diabetic foot ulcer prevention clinic over a 10-year period.

NFIA determines the -effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes.

Relationship of normal-weight central obesity with the risk for heart failure and atrial fibrillation: analysis of a nationwide health check-up and claims database.

Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men.

Major complications after percutaneous biopsy of native or transplanted liver in pediatric patients: a nationwide inpatient database study in Japan.

Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling.

Asymptomatic myocardial infarction in a patient with myotonic dystrophy type 1.

Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.

Impact of the COVID-19 pandemic on the glycemic control, eating habits, and body compositions of people with diabetes mellitus: A retrospective longitudinal observational study.

Impact of body mass index on in-hospital mortality in older patients hospitalized for bacterial pneumonia with non-dialysis-dependent chronic kidney disease.

Association of cardiovascular health metrics with annual incidence of prediabetes or diabetes: Analysis of a nationwide real-world database.

Diagnostic ability using fatty liver and metabolic markers for metabolic-associated fatty liver disease stratified by metabolic/glycemic abnormalities.

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes.

Age-Dependent Association Between Modifiable Risk Factors and Incident Cardiovascular Disease.

Intensified Multifactorial Intervention in Patients with Type 2 Diabetes Mellitus.

Progress in genetics of type 2 diabetes and diabetic complications.

Comparison of bleeding complications after pediatric kidney biopsy between intravenous sedation and general anesthesia: a nationwide cohort study.

Blood levels of nicotinic acid negatively correlate with hearing ability in healthy older men.

Development of a high-performance liquid chromatographic glycated albumin assay using finger-prick blood samples.

Associations of sleep quality with the skeletal muscle strength in patients with type 2 diabetes with poor glycemic control.

Evaluation of glycated albumin levels in tears and saliva as a marker in patients with diabetes mellitus.

A novel homozygous nonsense variant of LMF1 in pregnancy-induced hypertriglyceridemia with acute pancreatitis.

Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.

Impact of the COVID-19 pandemic on the glycemic control in people with diabetes mellitus: A retrospective cohort study.

Patient referral flow between physician and ophthalmologist visits for diabetic retinopathy screening among Japanese patients with diabetes: A retrospective cross-sectional cohort study using the National Database.