Roman J. Szczesny

Down-regulation of human RNA/DNA helicase SUV3 induces apoptosis by a caspase- and AIF-dependent pathway.

Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance.

The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

[Final doctorate competition 2009. Study of hSuv3p human helicase function].

Human Suv3 protein reveals unique features among SF2 helicases.

RNA degradation in yeast and human mitochondria.

Human mitochondrial RNA decay mediated by PNPase-hSuv3 complex takes place in distinct foci.

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels.

A new strategy for gene targeting and functional proteomics using the DT40 cell line.

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target.

Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease.

Two novel C-terminal frameshift mutations in the β-globin gene lead to rapid mRNA decay.

Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system.

Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria.

Mitochondrial double-stranded RNA triggers antiviral signalling in humans.

Controlling the mitochondrial antisense - role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance.

Quantitative proteomics revealed C6orf203/MTRES1 as a factor preventing stress-induced transcription deficiency in human mitochondria.

Mitochondrial Gene Expression and Beyond-Novel Aspects of Cellular Physiology.

Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA.

Loading messenger RNAs onto ribosomes in human mitochondria: lessons learned from a bacterial toxin.

High-Throughput Measurement of Mitochondrial RNA Turnover in Human Cultured Cells.

DNA Repair Protein APE1 Degrades Dysfunctional Abasic mRNA in Mitochondria Affecting Oxidative Phosphorylation.

Human Mitochondrial RNA Processing and Modifications: Overview.

Mitochondrial RNA, a new trigger of the innate immune system.

Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings.

In vitro reconstitution reveals a key role of human mitochondrial EXOG in RNA primer processing.