Department of Bioanalytical Ecotoxicology
I am a PhD student at the Center for Electromicrobiology at Aarhus University, Denmark and intrigued by the impact of electrogenic cable bacteria on the geochemistry of the rhizosphere in aquatic plants. The cable bacteria-plant interactions could have benefits, constraints, and even climate-relevant implications on a global scale.
Induction of vitellogenin in vivo and in vitro in the model teleost medaka (Oryzias latipes): comparison of gene expression and protein levels.
Marine environmental research Apr, 2004 | Pubmed ID: 14580810
Analysis of estrogenic effects by quantification of green fluorescent protein in juvenile fish of a transgenic medaka.
Environmental toxicology and chemistry Oct, 2005 | Pubmed ID: 16268157
Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae.
Aquatic toxicology (Amsterdam, Netherlands) Mar, 2007 | Pubmed ID: 17292976
The role of cyp1a and heme oxygenase 1 gene expression for the toxicity of 3,4-dichloroaniline in zebrafish (Danio rerio) embryos.
Aquatic toxicology (Amsterdam, Netherlands) Jan, 2008 | Pubmed ID: 18045703
The zebrafish embryo model in environmental risk assessment--applications beyond acute toxicity testing.
Environmental science and pollution research international Jul, 2008 | Pubmed ID: 18575912
Effects of endocrine disrupters on sexual, gonadal development in fish.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation , 2009 | Pubmed ID: 19684458
Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians--screening for estrogen, androgen and thyroid hormone disruption.
Critical reviews in toxicology Jan, 2013 | Pubmed ID: 23190036
A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment.
Regulatory toxicology and pharmacology : RTP Dec, 2013 | Pubmed ID: 24161465
OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing.
Regulatory toxicology and pharmacology : RTP Aug, 2014 | Pubmed ID: 24874798
Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos.
Aquatic toxicology (Amsterdam, Netherlands) Sep, 2014 | Pubmed ID: 24927039
Extensive review of fish embryo acute toxicities for the prediction of GHS acute systemic toxicity categories.
Regulatory toxicology and pharmacology : RTP Aug, 2014 | Pubmed ID: 24929227
Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).
Regulatory toxicology and pharmacology : RTP Dec, 2014 | Pubmed ID: 25261300
Comparative analysis of goitrogenic effects of phenylthiourea and methimazole in zebrafish embryos.
Reproductive toxicology (Elmsford, N.Y.) Nov, 2015 | Pubmed ID: 25962731
In Response: Quantitative adverse outcome pathways for prediction of adverse effects--An academic perspective.
Environmental toxicology and chemistry Sep, 2015 | Pubmed ID: 26313028
From the exposome to mechanistic understanding of chemical-induced adverse effects.
Environment international Feb, 2017 | Pubmed ID: 27939949
Applicability of the fish embryo acute toxicity (FET) test (OECD 236) in the regulatory context of Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH).
Environmental toxicology and chemistry Mar, 2018 | Pubmed ID: 29226368
Cellular Uptake Kinetics of Neutral and Charged Chemicals in in Vitro Assays Measured by Fluorescence Microscopy.
Chemical research in toxicology Aug, 2018 | Pubmed ID: 29939727
An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos.
PloS one , 2018 | Pubmed ID: 30157258
Automated Morphological Feature Assessment for Zebrafish Embryo Developmental Toxicity Screens.
Toxicological sciences : an official journal of the Society of Toxicology Feb, 2019 | Pubmed ID: 30295906
Zebrafish embryo and acute fish toxicity test show similar sensitivity for narcotic compounds.
ALTEX , 2019 | Pubmed ID: 30376146
Elemental imaging (LA-ICP-MS) of zebrafish embryos to study the toxicokinetics of the acetylcholinesterase inhibitor naled.
Analytical and bioanalytical chemistry Jan, 2019 | Pubmed ID: 30443774
DRomics: A Turnkey Tool to Support the Use of the Dose-Response Framework for Omics Data in Ecological Risk Assessment.
Environmental science & technology Dec, 2018 | Pubmed ID: 30444611
Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment.
Environmental toxicology and chemistry Sep, 2019 | Pubmed ID: 31127958
Diffraction-limited axial scanning in thick biological tissue with an aberration-correcting adaptive lens.
Scientific reports Jul, 2019 | Pubmed ID: 31267005
Comparative Assessment of the Sensitivity of Fish Early-Life Stage, Daphnia, and Algae Tests to the Chronic Ecotoxicity of Xenobiotics: Perspectives for Alternatives to Animal Testing.
Environmental toxicology and chemistry Jan, 2020 | Pubmed ID: 31598995
A multi-omics concentration-response framework uncovers novel understanding of triclosan effects in the chlorophyte Scenedesmus vacuolatus.
Journal of hazardous materials Oct, 2020 | Pubmed ID: 32361673
Yolk-Water Partitioning of Neutral Organic Compounds in the Model Organism Danio rerio.
Environmental toxicology and chemistry Aug, 2020 | Pubmed ID: 32383281
Yolk Sac of Zebrafish Embryos as Backpack for Chemicals?
Environmental science & technology 08, 2020 | Pubmed ID: 32639148
Optimization of the spontaneous tail coiling test for fast assessment of neurotoxic effects in the zebrafish embryo using an automated workflow in KNIME®.
Neurotoxicology and teratology , 2020 | Pubmed ID: 32730898
Chemical effects on dye efflux activity in live zebrafish embryos and on zebrafish Abcb4 ATPase activity.
FEBS letters Mar, 2021 | Pubmed ID: 33274443
Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines.
Chemical research in toxicology Sep, 2021 | Pubmed ID: 34357765
Photomotor response data analysis approach to assess chemical neurotoxicity with the zebrafish embryo.
ALTEX , 2022 | Pubmed ID: 34363684
Automated measurement of the spontaneous tail coiling of zebrafish embryos as a sensitive behavior endpoint using a workflow in KNIME.
MethodsX , 2021 | Pubmed ID: 34434841
The Eco-Exposome Concept: Supporting an Integrated Assessment of Mixtures of Environmental Chemicals.
Environmental toxicology and chemistry Jan, 2022 | Pubmed ID: 34714945
Inhibition of neurite outgrowth and enhanced effects compared to baseline toxicity in SH-SY5Y cells.
Archives of toxicology Apr, 2022 | Pubmed ID: 35182163
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network.
Computational toxicology (Amsterdam, Netherlands) Feb, 2022 | Pubmed ID: 35211661
The EU chemicals strategy for sustainability: an opportunity to develop new approaches for hazard and risk assessment.
Archives of toxicology Aug, 2022 | Pubmed ID: 35543751
Validation of an SH-SY5Y Cell-Based Acetylcholinesterase Inhibition Assay for Water Quality Assessment.
Environmental toxicology and chemistry Dec, 2022 | Pubmed ID: 36165561
A mechanistic understanding of the effects of polyethylene terephthalate nanoplastics in the zebrafish (Danio rerio) embryo.
Scientific reports Feb, 2023 | Pubmed ID: 36732581
Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods.
Archives of toxicology Mar, 2023 | Pubmed ID: 36952002
Monitoring Mixture Effects of Neurotoxicants in Surface Water and Wastewater Treatment Plant Effluents with Neurite Outgrowth Inhibition in SH-SY5Y Cells.
ACS environmental Au Nov, 2022 | Pubmed ID: 37101724
A metabolomics approach to reveal the mechanism of developmental toxicity in zebrafish embryos exposed to 6-propyl-2-thiouracil.
Chemico-biological interactions Sep, 2023 | Pubmed ID: 37236578
Uptake and Biotransformation of the Tire Rubber-derived Contaminants 6-PPD and 6-PPD Quinone in the Zebrafish Embryo ().
Environmental science & technology Oct, 2023 | Pubmed ID: 37782849
Analysis of vascular disruption in zebrafish embryos as an endpoint to predict developmental toxicity.
Archives of toxicology Dec, 2023 | Pubmed ID: 38129683
Gaëlle Hayot1,
Daniel Marcato1,2,
Christina A. Cramer von Clausbruch1,
Giuseppina Pace1,
Uwe Strähle1,3,
John K. Colbourne4,
Christian Pylatiuk5,
Ravindra Peravali1,
Carsten Weiss1,
Stefan Scholz6,
Thomas Dickmeis1
1Institute of Biological and Chemical Systems - Biological Information Processing, Karlsruhe Institute of Technology - Campus Nord,
2, DITABIS AG - Digital Biomedical Imaging Systems AG,
3Centre for Organismal Studies, Heidelberg University,
4School of Biosciences, University of Birmingham,
5Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology - Campus Nord,
6Department of Bioanalytical Ecotoxicology, Helmholtz-Centre for Environmental Research - UFZ
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