Research Group Immune Regulation,
Immune Regulation Group
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Neuropilin-1: a surface marker of regulatory T cells.
European journal of immunology Mar, 2004 | Pubmed ID: 14991591
CD4 T Lymphocyte-mediated lung disease: steady state between pathological and tolerogenic immune reactions.
American journal of respiratory and critical care medicine Dec, 2004 | Pubmed ID: 15306530
Characterization of a B220+ lymphoid cell subpopulation with immune modulatory functions in nasal-associated lymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2005 | Pubmed ID: 15661888
Intestinal immunity of Escherichia coli NISSLE 1917: a safe carrier for therapeutic molecules.
FEMS immunology and medical microbiology Mar, 2005 | Pubmed ID: 15708311
Multiple synergizing factors contribute to the strength of the CD8+ T cell response against listeriolysin O.
International immunology Jan, 2006 | Pubmed ID: 16291651
On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes.
Diabetes Dec, 2005 | Pubmed ID: 16306354
Lung epithelial NF-kappaB and Stat1 signaling in response to CD8+ T cell antigen recognition.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research May, 2006 | Pubmed ID: 16689660
G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2006 | Pubmed ID: 16785516
Cellular immunity and lung injury in respiratory virus infection.
Viral immunology , 2006 | Pubmed ID: 16817757
Autoimmune-mediated intestinal inflammation-impact and regulation of antigen-specific CD8+ T cells.
Gastroenterology Aug, 2006 | Pubmed ID: 16890605
Intestinal epithelial antigen induces CD4+ T cells with regulatory phenotype in a transgenic autoimmune mouse model.
Annals of the New York Academy of Sciences Aug, 2006 | Pubmed ID: 17057222
Phenotypic alterations in type II alveolar epithelial cells in CD4+ T cell mediated lung inflammation.
Respiratory research , 2007 | Pubmed ID: 17610738
Chronic antigen stimulation in vivo induces a distinct population of antigen-specific Foxp3 CD25 regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2007 | Pubmed ID: 18056346
Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity.
PloS one , 2007 | Pubmed ID: 18074031
Alveolar type II epithelial cells present antigen to CD4(+) T cells and induce Foxp3(+) regulatory T cells.
American journal of respiratory and critical care medicine Mar, 2009 | Pubmed ID: 19096007
Increased susceptibility for superinfection with Streptococcus pneumoniae during influenza virus infection is not caused by TLR7-mediated lymphopenia.
PloS one , 2009 | Pubmed ID: 19290047
Host genetic background strongly influences the response to influenza a virus infections.
PloS one , 2009 | Pubmed ID: 19293935
Frequency and gene expression profile of regulatory T cells in renal cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine , 2009 | Pubmed ID: 19609102
Novel reporter mouse reveals constitutive and inflammatory expression of IFN-beta in vivo.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2009 | Pubmed ID: 19667093
CX3CR1+ CD8alpha+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2010 | Pubmed ID: 20679228
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke.
Brain : a journal of neurology Mar, 2011 | Pubmed ID: 21354973
CD4+CD25+Foxp3+ regulatory T cells are dispensable for controlling CD8+ T cell-mediated lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2011 | Pubmed ID: 21518973
New insights into the molecular pathology of radiation-induced pneumopathy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology Oct, 2011 | Pubmed ID: 21722981
Human regulatory T cells in allogeneic stem cell transplantation.
Blood Sep, 2011 | Pubmed ID: 21778340
Therapeutic intervention in cancer and chronic viral infections: antibody mediated manipulation of PD-1/PD-L1 interaction.
Reviews on recent clinical trials Feb, 2012 | Pubmed ID: 22023178
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Nature Nov, 2011 | Pubmed ID: 22080947
Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.
BMC genomics , 2011 | Pubmed ID: 22182475
CD8+ T Cells Responding to Alveolar Self-Antigen Lack CD25 Expression and Fail to Precipitate Autoimmunity.
American journal of respiratory cell and molecular biology Dec, 2012 | Pubmed ID: 22984087
IL-4 attenuates pulmonary epithelial cell-mediated suppression of T cell priming.
PloS one , 2012 | Pubmed ID: 23029313
TLR7 Contributes to the Rapid Progression but Not to the Overall Fatal Outcome of Secondary Pneumococcal Disease following Influenza A Virus Infection.
Journal of innate immunity Nov, 2012 | Pubmed ID: 23154432
ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells.
BMC genomics Dec, 2012 | Pubmed ID: 23244505
Interferon regulatory factor-1 protects from fatal neurotropic infection with vesicular stomatitis virus by specific inhibition of viral replication in neurons.
PLoS pathogens Mar, 2014 | Pubmed ID: 24675692
Attenuation of immune-mediated influenza pneumonia by targeting the inducible co-stimulator (ICOS) molecule on T cells.
PloS one , 2014 | Pubmed ID: 25029240
Evidence for a causal link between adaptor protein PDZK1 downregulation and Na⁺/H⁺ exchanger NHE3 dysfunction in human and murine colitis.
Pflugers Archiv : European journal of physiology Aug, 2015 | Pubmed ID: 25271043
Ly6C(high) monocytes control cerebral toxoplasmosis.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2015 | Pubmed ID: 25710908
First genomic analysis of dendritic cells from lung and draining lymph nodes in murine asthma.
International journal of genomics , 2015 | Pubmed ID: 25811019
Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease.
Lung Dec, 2015 | Pubmed ID: 26319657
Erratum to: Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease.
Lung Dec, 2015 | Pubmed ID: 26459043
Modeling Influenza Virus Infection: A Roadmap for Influenza Research.
Viruses Oct, 2015 | Pubmed ID: 26473911
ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2016 | Pubmed ID: 26787852
Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals.
mBio May, 2016 | Pubmed ID: 27143386
Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies against Influenza-Pneumococcus Coinfection.
Frontiers in cellular and infection microbiology , 2016 | Pubmed ID: 27379214
ADAP plays a pivotal role in CD4+ T cell activation but is only marginally involved in CD8+ T cell activation, differentiation, and immunity to pathogens.
Journal of leukocyte biology 02, 2017 | Pubmed ID: 27605210
Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation.
Infection and immunity Dec, 2016 | Pubmed ID: 27647871
Mechanism of granuloma formation in sarcoidosis.
Current opinion in hematology 01, 2017 | Pubmed ID: 27755127
A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection.
Vaccine 12, 2016 | Pubmed ID: 27816372
Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course.
Lung 02, 2017 | Pubmed ID: 27864635
Hierarchical effects of pro-inflammatory cytokines on the post-influenza susceptibility to pneumococcal coinfection.
Scientific reports 11, 2016 | Pubmed ID: 27872472
Targeted antigen delivery to dendritic cells elicits robust antiviral T cell-mediated immunity in the liver.
Scientific reports Mar, 2017 | Pubmed ID: 28266658
c-REL and IκB Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors.
Journal of immunology (Baltimore, Md. : 1950) 08, 2017 | Pubmed ID: 28652399
IL-33: a jack of all trades in the orchestration of respiratory antibacterial immunity.
Cellular & molecular immunology Jul, 2017 | Pubmed ID: 28690328
Chronic lung inflammation primes humoral immunity and augments antipneumococcal resistance.
Scientific reports 07, 2017 | Pubmed ID: 28694492
Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation Toll-Like Receptor 7.
Frontiers in immunology , 2018 | Pubmed ID: 29497422
Proteomic definition of human mucosal-associated invariant T cells determines their unique molecular effector phenotype.
European journal of immunology 08, 2018 | Pubmed ID: 29749611
Respiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice.
International journal of molecular sciences Sep, 2018 | Pubmed ID: 30200513
Hemodialysis-related changes in phenotypical features of monocytes.
Scientific reports 09, 2018 | Pubmed ID: 30228352
Presence of Infected Gr-1CD11bCD11c Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in -Infected Mice.
Frontiers in immunology , 2018 | Pubmed ID: 30386330
Activates Human Mucosal-Associated Invariant T Cells.
Frontiers in microbiology , 2018 | Pubmed ID: 30410474
Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFI16 in cd44-/- tumor cells, MEFs and macrophages.
PloS one , 2018 | Pubmed ID: 30540779
Essential role of IκB for in vivo CD4 T-cell activation, proliferation, and Th1-cell differentiation during Listeria monocytogenes infection in mice.
European journal of immunology 09, 2019 | Pubmed ID: 31049948
The STING activator c-di-AMP exerts superior adjuvant properties than the formulation poly(I:C)/CpG after subcutaneous vaccination with soluble protein antigen or DEC-205-mediated antigen targeting to dendritic cells.
Vaccine 08, 2019 | Pubmed ID: 31320219
Neutralization of Pro-inflammatory Cytokines During Secondary Infection Post Influenza A Virus Infection.
Frontiers in immunology , 2019 | Pubmed ID: 31474978
Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge.
PLoS pathogens 09, 2019 | Pubmed ID: 31525249
ADAP Promotes Degranulation and Migration of NK Cells Primed During Infection in Mice.
Frontiers in immunology , 2019 | Pubmed ID: 32038647
Topological data analysis to model the shape of immune responses during co-infections.
Communications in nonlinear science & numerical simulation Jun, 2020 | Pubmed ID: 32288422
NMP4: a nuclear driver of innate inflammatory responses during influenza A virus infection.
Cellular & molecular immunology Dec, 2020 | Pubmed ID: 32747686
Eosinophilic pulmonary vasculitis as a manifestation of the hyperinflammatory phase of COVID-19.
The Journal of allergy and clinical immunology 01, 2021 | Pubmed ID: 33139059
Resolved Influenza A Virus Infection Has Extended Effects on Lung Homeostasis and Attenuates Allergic Airway Inflammation in a Mouse Model.
Microorganisms Nov, 2020 | Pubmed ID: 33260910
Julia Volckmar1,2,
Laura Knop1,2,3,
Tatjana Hirsch1,
Sarah Frentzel1,2,
Christian Erck4,
Marco van Ham4,
Sabine Stegemann-Koniszewski*,1,2,5,
Dunja Bruder*,1,2
1Immune Regulation Group, Helmholtz Centre for Infection Research,
2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg,
3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg,
4Cellular Proteome Research, Helmholtz Centre for Infection Research,
5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg
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