Tamar Kleinberger

Adenovirus and cell cycle control.

Using the Ras Recruitment System to identify PP2A-B55-interacting proteins.

The scaffolding A/Tpd3 subunit and high phosphatase activity are dispensable for Cdc55 function in the Saccharomyces cerevisiae spindle checkpoint and in cytokinesis.

YND1 interacts with CDC55 and is a novel mediator of E4orf4-induced toxicity.

Adenovirus E4orf4 protein downregulates MYC expression through interaction with the PP2A-B55 subunit.

The cytosolic tail of the Golgi apyrase Ynd1 mediates E4orf4-induced toxicity in Saccharomyces cerevisiae.

The adenovirus E4orf4 protein targets PP2A to the ACF chromatin-remodeling factor and induces cell death through regulation of SNF2h-containing complexes.