Piero Marchetti

Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells.

p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress.

Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.

Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.

Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes.

The emerging role of autophagy in the pathophysiology of diabetes mellitus.

EuroDia: a beta-cell gene expression resource.

Pancreas rejection after pandemic influenzavirus A(H1N1) vaccination or infection: a report of two cases.

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.

Segmental live donor pancreas transplantation: review and critique of rationale, outcomes, and current recommendations.

Neutralizing interleukin-1beta (IL-1beta) induces beta-cell survival by maintaining PDX1 protein nuclear localization.

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis.

ENPP1 affects insulin action and secretion: evidences from in vitro studies.

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death.

Current perspectives on laparoscopic robot-assisted pancreas and pancreas-kidney transplantation.

Histopathology and ex vivo insulin secretion of pancreatic islets in gestational diabetes: A case report.

Zinc transporter 8 autoantibodies increase the predictive value of islet autoantibodies for function loss of technically successful solitary pancreas transplant.

Pleiotropic effects of GIP on islet function involve osteopontin.

Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.

PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.

Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus.

Results of pancreas transplantation alone with special attention to native kidney function and proteinuria in type 1 diabetes patients.

Nanomedicine for treatment of diabetes in an aging population: state-of-the-art and future developments.

Laparoscopic robot-assisted pancreas transplantation: first world experience.

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

Long-term (5 years) efficacy and safety of pancreas transplantation alone in type 1 diabetic patients.

The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets.

Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.

Nanomedicine for treatment of diabetes in an aging population: state-of-the-art and future developments.

ECTOPIC EXPRESSION OF FSH RECEPTOR ISOFORMS IN NEOPLASTIC BUT NOT IN ENDOTHELIAL CELLS FROM PANCREATIC NEUROENDOCRINE TUMOURS.

Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.

Transplantation of the pancreas.

Guidelines for the use and interpretation of assays for monitoring autophagy.

From genotype to human β cell phenotype and beyond.

Ultrastructural morphometric analysis of insulin secretory granules in human type 2 diabetes.

Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.

Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetes.

Follow-up of secondary diabetic complications after pancreas transplantation.