Molecular Diabetology
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Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells.
The Journal of biological chemistry Jul, 2003 | Pubmed ID: 12682071
Secretory granules: and the last shall be first...
Trends in cell biology Aug, 2003 | Pubmed ID: 12888291
Rhabdomyolysis and paraneoplastic stiff-man syndrome with amphiphysin autoimmunity.
Annals of neurology Feb, 2004 | Pubmed ID: 14755734
Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis.
Nature cell biology Mar, 2004 | Pubmed ID: 15039777
BetaIV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2004 | Pubmed ID: 15317849
BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.
The Journal of cell biology Sep, 2004 | Pubmed ID: 15381686
Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells.
The Journal of cell biology Dec, 2004 | Pubmed ID: 15596545
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway.
The Journal of cell biology Aug, 2005 | Pubmed ID: 16103228
Effect of oxygenated perfluorocarbons on isolated rat pancreatic islets in culture.
Cell transplantation , 2005 | Pubmed ID: 16285252
cAMP-dependent phosphorylation of PTB1 promotes the expression of insulin secretory granule proteins in beta cells.
Cell metabolism Feb, 2006 | Pubmed ID: 16459313
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5.
Nature cell biology May, 2006 | Pubmed ID: 16622421
Genes of type 2 diabetes in beta cells.
Endocrinology and metabolism clinics of North America Jun, 2006 | Pubmed ID: 16632098
Biogenesis of secretory granules.
Current opinion in cell biology Aug, 2006 | Pubmed ID: 16806882
ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2008 | Pubmed ID: 18178618
ICA69 is a novel Rab2 effector regulating ER-Golgi trafficking in insulinoma cells.
European journal of cell biology Apr, 2008 | Pubmed ID: 18187231
Pancreas islets in metabolic signaling--focus on the beta-cell.
Frontiers in bioscience : a journal and virtual library , 2008 | Pubmed ID: 18508724
Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.
The Journal of biological chemistry Nov, 2008 | Pubmed ID: 18824546
Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells.
Molecular & cellular proteomics : MCP Mar, 2009 | Pubmed ID: 18854578
beta-Cells at the crossroads: choosing between insulin granule production and proliferation.
Diabetes, obesity & metabolism Nov, 2009 | Pubmed ID: 19817789
Automated suppression of sample-related artifacts in Fluorescence Correlation Spectroscopy.
Optics express May, 2010 | Pubmed ID: 20588964
The insulin secretory granule as a signaling hub.
Trends in endocrinology and metabolism: TEM Oct, 2010 | Pubmed ID: 20609596
Insulin release: shedding light on a complex matter.
Cell metabolism Jul, 2010 | Pubmed ID: 20620989
β2-Syntrophin is a Cdk5 substrate that restrains the motility of insulin secretory granules.
PloS one , 2010 | Pubmed ID: 20886068
Tamoxifen-independent recombination in the RIP-CreER mouse.
PloS one , 2010 | Pubmed ID: 21063464
Impaired insulin turnover in islets from type 2 diabetic patients.
Islets Jan-Feb, 2010 | Pubmed ID: 21099291
Human stiff-person syndrome IgG induces anxious behavior in rats.
PloS one , 2011 | Pubmed ID: 21346811
PTBP1 is required for embryonic development before gastrulation.
PloS one , 2011 | Pubmed ID: 21423341
Functional assessment of automatically sorted pancreatic islets using large particle flow cytometry.
Islets Sep-Oct, 2011 | Pubmed ID: 21799307
Protein-protein interactions in crystals of the human receptor-type protein tyrosine phosphatase ICA512 ectodomain.
PloS one , 2011 | Pubmed ID: 21935384
Dorothée Sturm1,2,
Lorella Marselli3,
Florian Ehehalt1,2,
Daniela Richter1,
Marius Distler2,
Stephan Kersting1,2,
Robert Grützmann2,
Krister Bokvist4,
Philippe Froguel5,
Robin Liechti6,
Anne Jörns7,
Paolo Meda8,
Gustavo Bruno Baretton9,
Hans-Detlev Saeger2,
Anke M. Schulte10,
Piero Marchetti3,
Michele Solimena1
1Molecular Diabetology, Paul Langerhans Institute Dresden,
2Department of GI-, Thoracic- and Vascular Surgery, University Hospital Carl Gustav Carus, University of Technology Dresden,
3Department of Endocrinology and Metabolism, Metabolic Unit University of Pisa,
4Labs DC0522, Lilly Corporate Center,
5Genomics, Faculty of Medicine Imperial College London,
6Vital-IT, SIB Swiss Institute of Bioinformatics,
7Clinical Biochemistry, Hannover Medical School,
8Cell Physiology and Metabolism, Medical School, University of Geneva,
9Department of Pathology, University Hospital Carl Gustav Carus, University of Technology Dresden,
10R&D DIAB Division / Translational Medicine, Sanofi-Aventis
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