Tomas Olsson

Prior poliomyelitis-IVIg treatment reduces proinflammatory cytokine production.

T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis.

An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci.

MHC class II isotype- and allele-specific attenuation of experimental autoimmune encephalomyelitis.

Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro.

MHC and non-MHC gene regulation of disease susceptibility and disease course in experimental inflammatory peripheral neuropathy.

Parental age, family size, and risk of multiple sclerosis.

Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block.

Resolution of a 16.8-Mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyelitis quantitative trait loci and evidence for epistasis.

Eae19, a new locus on rat chromosome 15 regulating experimental autoimmune encephalomyelitis.

MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction.

Genetic dissection of neurodegeneration and CNS inflammation.

Expression of T cell immunoglobulin- and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems.

Immunological patterns identifying disease course and evolution in multiple sclerosis patients.

CDR3 sequence preference of TCRBV8S2+ T cells within the CNS does not reflect single amino acid dependent avidity expansion.

CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin.

Effects of long term NOS inhibition on disease and the immune system in MOG induced EAE.

Cytokine responses during chronic denervation.

Neurogenesis in the adult spinal cord in an experimental model of multiple sclerosis.

Effect of intravenous immunoglobulin in patients with post-polio syndrome -- an uncontrolled pilot study.

Definition of a 1.06-Mb region linked to neuroinflammation in humans, rats and mice.

Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis.

[New era for MS treatment. Severe setback when it comes to enthusiasm--highly effective agent caused serious adverse effects].

Intravenous immunoglobulin for post-polio syndrome: a randomised controlled trial.

Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis.

Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes.

Genetics of autoimmune neuroinflammation.

Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat.

Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related.

Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE.

Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis.

Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia.

Neurofascin as a novel target for autoantibody-mediated axonal injury.

Vra4 congenic rats with allelic differences in the class II transactivator gene display altered susceptibility to experimental autoimmune encephalomyelitis.

Increased prevalence of multiple sclerosis among COPD patients and their first-degree relatives: a population-based study.

Progress and prospects in rat genetics: a community view.

Host strain-dependent difference in susceptibility in a rat model of herpes simplex type 1 encephalitis.

The genetics of multiple sclerosis and its experimental models.

Both MHC and non-MHC genes regulate development of experimental neuropathic pain in rats.

Contrasting genetic effects of major histocompatibility complex on ischemic peripheral nerve and spinal cord injury in female rats.

A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock.

Identification of novel candidate protein biomarkers for the post-polio syndrome - implications for diagnosis, neurodegeneration and neuroinflammation.

Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis.

Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome.

TLR activation induces TNF-alpha production from adult neural stem/progenitor cells.

Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.

Differential nerve injury-induced expression of MHC class II in the mouse correlates to genetic variability in the type I promoter of C2ta.

Differential expression, and genetic association, of CD58 in Swedish multiple sclerosis patients.

Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury.

Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis.

Progressive multifocal leukoencephalopathy after natalizumab monotherapy.

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

Alternative splicing and transcriptome profiling of experimental autoimmune encephalomyelitis using genome-wide exon arrays.

Gene expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?

Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers.

Interleukin 18 receptor 1 expression distinguishes patients with multiple sclerosis.

A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis.

Management of postpolio syndrome.

Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis.

TNF production in macrophages is genetically determined and regulates inflammatory disease in rats.

Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice.

Confirmation of association between multiple sclerosis and CYP27B1.

Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block.

Influence of perineurial cells and Toll-like receptors 2 and 9 on Herpes simplex type 1 entry to the central nervous system in rat encephalitis.

Considerations on discontinuing natalizumab for the treatment of multiple sclerosis.

Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat.

Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis.

IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation.

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.

A Swedish national post-marketing surveillance study of natalizumab treatment in multiple sclerosis.

Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab.

Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis.

Principles of a new treatment algorithm in multiple sclerosis.

Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders.

White matter disease: Roles of anti-MOG antibodies in demyelinating diseases.

The expression of VEGF-A is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosis.

Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655.

Detecting oxysterols in the human circulation.

MRM assay for quantitation of complement components in human blood plasma - a feasibility study on multiple sclerosis.

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development.

Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern.

Randomized trial of oral teriflunomide for relapsing multiple sclerosis.

Shift work at young age is associated with increased risk for multiple sclerosis.

The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls.

Risk stratification for progressive multifocal leukoencephalopathy in patients treated with natalizumab.

High body mass index before age 20 is associated with increased risk for multiple sclerosis in both men and women.

Targeting free prostate-specific antigen for in vivo imaging of prostate cancer using a monoclonal antibody specific for unique epitopes accessible on free prostate-specific antigen alone.

Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis.

Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis.

Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation.

Pre-specified subgroup analyses of a placebo-controlled phase III trial (TEMSO) of oral teriflunomide in relapsing multiple sclerosis.

The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat.

Intravenous immunoglobulin treatment of the post-polio syndrome: sustained effects on quality of life variables and cytokine expression after one year follow up.

Expression of Ccl11 associates with immune response modulation and protection against neuroinflammation in rats.

Lack of replication of interaction between EBNA1 IgG and smoking in risk for multiple sclerosis.

Low serum levels of vitamin D in idiopathic inflammatory myopathies.

Serum levels of LIGHT in MS.

Neurofascin as a target for autoantibodies in peripheral neuropathies.

CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis.

The DQB1 *03:02 HLA haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation.

Effects of natalizumab treatment on the cerebrospinal fluid proteome of multiple sclerosis patients.

Imatinib ameliorates neuroinflammation in a rat model of multiple sclerosis by enhancing blood-brain barrier integrity and by modulating the peripheral immune response.

Magnetic resonance imaging outcomes from a phase III trial of teriflunomide.

Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort.

Changes to anti-JCV antibody levels in a Swedish national MS cohort.

Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17- and activated B-cells and correlates with progression.

Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.

Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity.

Cerebrospinal fluid oligoclonal bands are important in the diagnosis of multiple sclerosis, unreasonably downplayed by the McDonald criteria 2010: Yes.

Intense inflammation and nerve damage in early multiple sclerosis subsides at older age: a reflection by cerebrospinal fluid biomarkers.

Antibody-based profiling of cerebrospinal fluid within multiple sclerosis.

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.

Autoantibody profiling in multiple sclerosis using arrays of human protein fragments.

Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients.

Teriflunomide reduces relapse-related neurological sequelae, hospitalizations and steroid use.

Combining genetic mapping with genome-wide expression in experimental autoimmune encephalomyelitis highlights a gene network enriched for T cell functions and candidate genes regulating autoimmunity.

Smoking and risk of treatment-induced neutralizing antibodies to interferon β-1a.

Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases.

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Teriflunomide versus subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis: a randomised, controlled phase 3 trial.

Smoking and multiple sclerosis susceptibility.

Fatty fish intake is associated with decreased occurrence of multiple sclerosis.

Mortality following a brain tumour diagnosis in patients with multiple sclerosis.

Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.

Alcohol as a modifiable lifestyle factor affecting multiple sclerosis risk.

Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial.

A/H1N1 antibodies and TRIB2 autoantibodies in narcolepsy patients diagnosed in conjunction with the Pandemrix vaccination campaign in Sweden 2009-2010.

Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis.

Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment.

Natural polymorphisms in Tap2 influence negative selection and CD4∶CD8 lineage commitment in the rat.

Smoking and risk of multiple sclerosis: evidence of modification by NAT1 variants.

High-resolution genome screen for bone mineral density in heterogeneous stock rat.

Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE).

Oral ponesimod in relapsing-remitting multiple sclerosis: a randomised phase II trial.

HLA-A(∗)02, gender and tobacco smoking, but not multiple sclerosis, affects the IgG antibody response against human herpesvirus 6.

Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy.

JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants.

Interferon beta treatment of multiple sclerosis increases serum interleukin-7.

Age-dependent effects on the treatment response of natalizumab in MS patients.

Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research.

Teriflunomide reduces relapses with sequelae and relapses leading to hospitalizations: results from the TOWER study.

Neonatal vitamin D status and risk of multiple sclerosis.

Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general.

A cell culture model for monitoring α-synuclein cell-to-cell transfer.

No association between rheumatoid arthritis, amyotrophic lateral sclerosis, and tumour necrosis factor inhibitor treatment.

Signaling networks in MS: a systems-based approach to developing new pharmacological therapies.

Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort.

Oral teriflunomide for patients with a first clinical episode suggestive of multiple sclerosis (TOPIC): a randomised, double-blind, placebo-controlled, phase 3 trial.

Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis.

Obesity during childhood and adolescence increases susceptibility to multiple sclerosis after accounting for established genetic and environmental risk factors.

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells.

Interaction between passive smoking and two HLA genes with regard to multiple sclerosis risk.

Initial lymphocyte count and low BMI may affect fingolimod-induced lymphopenia.

β-Amyloid peptides and amyloid plaques in Alzheimer's disease.

Natalizumab exerts a suppressive effect on surrogates of B cell function in blood and CSF.

Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis.

The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.

Genetic variants are major determinants of CSF antibody levels in multiple sclerosis.

Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes.

The Role of Environment and Lifestyle in Determining the Risk of Multiple Sclerosis.

Complement component C3 and butyrylcholinesterase activity are associated with neurodegeneration and clinical disability in multiple sclerosis.

γ-Secretase directly sheds the survival receptor BCMA from plasma cells.

Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms.

Cell Fusion along the Anterior-Posterior Neuroaxis in Mice with Experimental Autoimmune Encephalomyelitis.

Fine mapping of bone structure and strength QTLs in heterogeneous stock rat.

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Effect of Smoking Cessation on Multiple Sclerosis Prognosis.

PML: The Dark Side of Immunotherapy in Multiple Sclerosis.

MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated.

Rat bone marrow-derived dendritic cells generated with GM-CSF/IL-4 or FLT3L exhibit distinct phenotypical and functional characteristics.

A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.

The Expression of BAFF Is Controlled by IRF Transcription Factors.

Translational utility of experimental autoimmune encephalomyelitis: recent developments.

Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.

Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination.

Posterior Accumulation of Tau and Concordant Hypometabolism in an Early-Onset Alzheimer's Disease Patient with Presenilin-1 Mutation.

Pooled safety and tolerability data from four placebo-controlled teriflunomide studies and extensions.

[New techniques can radically change health care].

Anoctamin 2 identified as an autoimmune target in multiple sclerosis.

High-intensity resistance training in multiple sclerosis - An exploratory study of effects on immune markers in blood and cerebrospinal fluid, and on mood, fatigue, health-related quality of life, muscle strength, walking and cognition.

Cerebrospinal fluid biomarkers of inflammation and degeneration as measures of fingolimod efficacy in multiple sclerosis.

Environmental factors and their interactions with risk genotypes in MS susceptibility.

Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis.

Multiple sclerosis and risk of young-adult-onset Hodgkin lymphoma.

Autoantibody targets in vaccine-associated narcolepsy.

Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis.

Multiple sclerosis relapses are associated with increased fatigue and reduced health-related quality of life - A post hoc analysis of the TEMSO and TOWER studies.

Effect of high-dose vitamin D3 supplementation on antibody responses against Epstein-Barr virus in relapsing-remitting multiple sclerosis.

Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins.

T-cell activation and HLA-regulated response to smoking in the deep airways of patients with multiple sclerosis.

Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS.

TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells.

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies.

Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis.

Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk.

IL-22 binding protein regulates murine skin inflammation.

Increased basal ganglia binding of (18) F-AV-1451 in patients with progressive supranuclear palsy.

Modeling strategies for quantification of in vivo 18F-AV1451 binding in patients with tau pathology.

Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing-remitting multiple sclerosis.