Tomas Olsson

Department of Clinical Neuroscience, Karolinska Institutet

Research Area

Neuroscience

Biography

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JoVE Journal Publications

Article Total : 1	Year
Publication title	2016

Other Publications

Article	Year
Prior poliomyelitis-IVIg treatment reduces proinflammatory cytokine production. Journal of neuroimmunology\| PubMed ID: 15081258	2004
T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in ... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15153541	2004
An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15240732	2004
MHC class II isotype- and allele-specific attenuation of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15294998	2004
Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro. The European journal of neuroscience\| PubMed ID: 15341591	2004
MHC and non-MHC gene regulation of disease susceptibility and disease course in experimental inflammatory peripheral neuropathy. Journal of neuroimmunology\| PubMed ID: 15342198	2004
Parental age, family size, and risk of multiple sclerosis. Epidemiology (Cambridge, Mass.)\| PubMed ID: 15475721	2004
Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block. The Journal of experimental medicine\| PubMed ID: 15630133	2005
Resolution of a 16.8-Mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyelitis quantitative trait loci and evidence for epistasis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15634914	2005
Eae19, a new locus on rat chromosome 15 regulating experimental autoimmune encephalomyelitis. Genetics\| PubMed ID: 15716504	2005
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction. Nature genetics\| PubMed ID: 15821736	2005
Genetic dissection of neurodegeneration and CNS inflammation. Journal of the neurological sciences\| PubMed ID: 15894332	2005
Expression of T cell immunoglobulin- and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems. Journal of neuroimmunology\| PubMed ID: 15913792	2005
Immunological patterns identifying disease course and evolution in multiple sclerosis patients. Journal of neuroimmunology\| PubMed ID: 15949850	2005
CDR3 sequence preference of TCRBV8S2+ T cells within the CNS does not reflect single amino acid dependent avidity expansion. Journal of neuroimmunology\| PubMed ID: 15963573	2005
CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin. Journal of neuroinflammation\| PubMed ID: 16053521	2005
Effects of long term NOS inhibition on disease and the immune system in MOG induced EAE. Nitric oxide : biology and chemistry\| PubMed ID: 16102987	2005
Cytokine responses during chronic denervation. Journal of neuroinflammation\| PubMed ID: 16287511	2005
Neurogenesis in the adult spinal cord in an experimental model of multiple sclerosis. The European journal of neuroscience\| PubMed ID: 16420447	2006
Effect of intravenous immunoglobulin in patients with post-polio syndrome -- an uncontrolled pilot study. Journal of rehabilitation medicine\| PubMed ID: 16546773	2006
Definition of a 1.06-Mb region linked to neuroinflammation in humans, rats and mice. Genetics\| PubMed ID: 16624898	2006
Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16670314	2006
[New era for MS treatment. Severe setback when it comes to enthusiasm--highly effective agent caused serious adverse effects]. Lakartidningen\| PubMed ID: 16708855	2006
Intravenous immunoglobulin for post-polio syndrome: a randomised controlled trial. The Lancet. Neurology\| PubMed ID: 16713921	2006
Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis. Stem cells (Dayton, Ohio)\| PubMed ID: 16916924	2006
Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes. Neurobiology of disease\| PubMed ID: 16934480	2006
Genetics of autoimmune neuroinflammation. Current opinion in immunology\| PubMed ID: 16973343	2006
Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat. Genomics\| PubMed ID: 17010567	2006
Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related. Journal of neuropathology and experimental neurology\| PubMed ID: 17146287	2006
Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE. Journal of neuroinflammation\| PubMed ID: 17484785	2007
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nature genetics\| PubMed ID: 17660816	2007
Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia. Pain\| PubMed ID: 17764842	2008
Neurofascin as a novel target for autoantibody-mediated axonal injury. The Journal of experimental medicine\| PubMed ID: 17846150	2007
Vra4 congenic rats with allelic differences in the class II transactivator gene display altered susceptibility to experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18292553	2008
Increased prevalence of multiple sclerosis among COPD patients and their first-degree relatives: a population-based study. Lung\| PubMed ID: 18351419	2008
Progress and prospects in rat genetics: a community view. Nature genetics\| PubMed ID: 18443588	2008
Host strain-dependent difference in susceptibility in a rat model of herpes simplex type 1 encephalitis. Journal of neurovirology\| PubMed ID: 18444082	2008
The genetics of multiple sclerosis and its experimental models. Current opinion in neurology\| PubMed ID: 18451707	2008
Both MHC and non-MHC genes regulate development of experimental neuropathic pain in rats. Neuroscience letters\| PubMed ID: 18640240	2008
Contrasting genetic effects of major histocompatibility complex on ischemic peripheral nerve and spinal cord injury in female rats. Neuroscience letters\| PubMed ID: 18675884	2008
A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock. Genome research\| PubMed ID: 18971309	2009
Identification of novel candidate protein biomarkers for the post-polio syndrome - implications for diagnosis, neurodegeneration and neuroinflammation. Journal of proteomics\| PubMed ID: 19100873	2009
Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis. Journal of neuroimmunology\| PubMed ID: 19269041	2009
Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19299744	2009
TLR activation induces TNF-alpha production from adult neural stem/progenitor cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19454685	2009
Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis. Respiratory research\| PubMed ID: 19480659	2009
Differential nerve injury-induced expression of MHC class II in the mouse correlates to genetic variability in the type I promoter of C2ta. Journal of neuroimmunology\| PubMed ID: 19481818	2009
Differential expression, and genetic association, of CD58 in Swedish multiple sclerosis patients. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19497873	2009
Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury. Journal of neuroimmunology\| PubMed ID: 19525015	2009
Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis. Neurology\| PubMed ID: 19720976	2009
Progressive multifocal leukoencephalopathy after natalizumab monotherapy. The New England journal of medicine\| PubMed ID: 19741229	2009
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis. European journal of human genetics : EJHG\| PubMed ID: 19888296	2010
Alternative splicing and transcriptome profiling of experimental autoimmune encephalomyelitis using genome-wide exon arrays. PloS one\| PubMed ID: 19915720	2009
Gene expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery? Neurobiology of disease\| PubMed ID: 19944761	2010
Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers. Journal of proteomics\| PubMed ID: 20093204	2010
Interleukin 18 receptor 1 expression distinguishes patients with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 20354066	2010
A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis. Science translational medicine\| PubMed ID: 20368159	2009
Management of postpolio syndrome. The Lancet. Neurology\| PubMed ID: 20494327	2010
Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. Nature genetics\| PubMed ID: 20502484	2010
TNF production in macrophages is genetically determined and regulates inflammatory disease in rats. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20505148	2010
Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice. Autoimmunity reviews\| PubMed ID: 20601202	2010
Confirmation of association between multiple sclerosis and CYP27B1. European journal of human genetics : EJHG\| PubMed ID: 20648053	2010
Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20696861	2010
Influence of perineurial cells and Toll-like receptors 2 and 9 on Herpes simplex type 1 entry to the central nervous system in rat encephalitis. PloS one\| PubMed ID: 20806060	2010
Considerations on discontinuing natalizumab for the treatment of multiple sclerosis. Annals of neurology\| PubMed ID: 20818795	2010
Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat. PloS one\| PubMed ID: 20856809	2010
Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 20921238	2011
IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21041731	2010
Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21135023	2011
A Swedish national post-marketing surveillance study of natalizumab treatment in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21228027	2011
Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab. Annals of neurology\| PubMed ID: 21280078	2011
Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 21303861	2011
Principles of a new treatment algorithm in multiple sclerosis. Expert review of neurotherapeutics\| PubMed ID: 21375441	2011
Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders. PloS one\| PubMed ID: 21533133	2011
White matter disease: Roles of anti-MOG antibodies in demyelinating diseases. Nature reviews. Neurology\| PubMed ID: 21537356	2011
The expression of VEGF-A is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosis. PloS one\| PubMed ID: 21573104	2011
Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655. European journal of human genetics : EJHG\| PubMed ID: 21610746	2011
Detecting oxysterols in the human circulation. Nature immunology\| PubMed ID: 21685947	2011
MRM assay for quantitation of complement components in human blood plasma - a feasibility study on multiple sclerosis. Journal of proteomics\| PubMed ID: 21703369	2011
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature\| PubMed ID: 21833088	2011
The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development. The Journal of experimental medicine\| PubMed ID: 21948080	2011
Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern. Annals of the rheumatic diseases\| PubMed ID: 21953338	2012
Randomized trial of oral teriflunomide for relapsing multiple sclerosis. The New England journal of medicine\| PubMed ID: 21991951	2011
Shift work at young age is associated with increased risk for multiple sclerosis. Annals of neurology\| PubMed ID: 22006815	2011
The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls. Genome medicine\| PubMed ID: 22264340	2012
Risk stratification for progressive multifocal leukoencephalopathy in patients treated with natalizumab. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22312009	2012
High body mass index before age 20 is associated with increased risk for multiple sclerosis in both men and women. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22328681	2012
Targeting free prostate-specific antigen for in vivo imaging of prostate cancer using a monoclonal antibody specific for unique epitopes accessible on free prostate-specific antigen alone. Cancer biotherapy & radiopharmaceuticals\| PubMed ID: 22489659	2012
Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 22561643	2012
Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis. PloS one\| PubMed ID: 22586495	2012
Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation. Science translational medicine\| PubMed ID: 22674551	2012
Pre-specified subgroup analyses of a placebo-controlled phase III trial (TEMSO) of oral teriflunomide in relapsing multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22723573	2012
The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat. PLoS pathogens\| PubMed ID: 22761571	2012
Intravenous immunoglobulin treatment of the post-polio syndrome: sustained effects on quality of life variables and cytokine expression after one year follow up. Journal of neuroinflammation\| PubMed ID: 22776106	2012
Expression of Ccl11 associates with immune response modulation and protection against neuroinflammation in rats. PloS one\| PubMed ID: 22815714	2012
Lack of replication of interaction between EBNA1 IgG and smoking in risk for multiple sclerosis. Neurology\| PubMed ID: 22933744	2012
Low serum levels of vitamin D in idiopathic inflammatory myopathies. Annals of the rheumatic diseases\| PubMed ID: 22993226	2013
Serum levels of LIGHT in MS. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23037546	2013
Neurofascin as a target for autoantibodies in peripheral neuropathies. Neurology\| PubMed ID: 23100406	2012
CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23178691	2013
The DQB1 *03:02 HLA haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation. Pain\| PubMed ID: 23318129	2013
Effects of natalizumab treatment on the cerebrospinal fluid proteome of multiple sclerosis patients. Journal of proteome research\| PubMed ID: 23339689	2013
Imatinib ameliorates neuroinflammation in a rat model of multiple sclerosis by enhancing blood-brain barrier integrity and by modulating the peripheral immune response. PloS one\| PubMed ID: 23437178	2013
Magnetic resonance imaging outcomes from a phase III trial of teriflunomide. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23447359	2013
Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23459571	2013
Changes to anti-JCV antibody levels in a Swedish national MS cohort. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 23463870	2013
Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17- and activated B-cells and correlates with progression. PloS one\| PubMed ID: 23469245	2013
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles. PloS one\| PubMed ID: 23472185	2013
Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23610432	2013
Cerebrospinal fluid oligoclonal bands are important in the diagnosis of multiple sclerosis, unreasonably downplayed by the McDonald criteria 2010: Yes. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23658235	2013
Intense inflammation and nerve damage in early multiple sclerosis subsides at older age: a reflection by cerebrospinal fluid biomarkers. PloS one\| PubMed ID: 23667585	2013
Antibody-based profiling of cerebrospinal fluid within multiple sclerosis. Proteomics\| PubMed ID: 23696371	2013
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature genetics\| PubMed ID: 23708188	2013
Autoantibody profiling in multiple sclerosis using arrays of human protein fragments. Molecular & cellular proteomics : MCP\| PubMed ID: 23732997	2013
Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. PloS one\| PubMed ID: 23785401	2013
Teriflunomide reduces relapse-related neurological sequelae, hospitalizations and steroid use. Journal of neurology\| PubMed ID: 23852658	2013
Combining genetic mapping with genome-wide expression in experimental autoimmune encephalomyelitis highlights a gene network enriched for T cell functions and candidate genes regulating auto... Human molecular genetics\| PubMed ID: 23900079	2013
Smoking and risk of treatment-induced neutralizing antibodies to interferon β-1a. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23924603	2014
Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24014878	2013
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature genetics\| PubMed ID: 24076602	2013
Teriflunomide versus subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis: a randomised, controlled phase 3 trial. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24126064	2014
Smoking and multiple sclerosis susceptibility. European journal of epidemiology\| PubMed ID: 24146047	2013
Fatty fish intake is associated with decreased occurrence of multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24158977	2014
Mortality following a brain tumour diagnosis in patients with multiple sclerosis. BMJ open\| PubMed ID: 24220114	2013
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects. PLoS genetics\| PubMed ID: 24278027	2013
Alcohol as a modifiable lifestyle factor affecting multiple sclerosis risk. JAMA neurology\| PubMed ID: 24395432	2014
Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet. Neurology\| PubMed ID: 24461574	2014
A/H1N1 antibodies and TRIB2 autoantibodies in narcolepsy patients diagnosed in conjunction with the Pandemrix vaccination campaign in Sweden 2009-2010. Journal of autoimmunity\| PubMed ID: 24485154	2014
Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis. Neurology\| PubMed ID: 24500647	2014
Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment. Genome medicine\| PubMed ID: 24571673	2014
Natural polymorphisms in Tap2 influence negative selection and CD4∶CD8 lineage commitment in the rat. PLoS genetics\| PubMed ID: 24586191	2014
Smoking and risk of multiple sclerosis: evidence of modification by NAT1 variants. Epidemiology (Cambridge, Mass.)\| PubMed ID: 24625537	2014
High-resolution genome screen for bone mineral density in heterogeneous stock rat. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 24643965	2014
Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Drug development research\| PubMed ID: 24648292	2014
Oral ponesimod in relapsing-remitting multiple sclerosis: a randomised phase II trial. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 24659797	2014
HLA-A(∗)02, gender and tobacco smoking, but not multiple sclerosis, affects the IgG antibody response against human herpesvirus 6. Human immunology\| PubMed ID: 24662416	2014
Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy. Annals of neurology\| PubMed ID: 24729444	2014
JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. PLoS pathogens\| PubMed ID: 24763718	2014
Interferon beta treatment of multiple sclerosis increases serum interleukin-7. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24821684	2014
Age-dependent effects on the treatment response of natalizumab in MS patients. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24866201	2015
Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research. BMC genomics\| PubMed ID: 24885425	2014
Teriflunomide reduces relapses with sequelae and relapses leading to hospitalizations: results from the TOWER study. Journal of neurology\| PubMed ID: 24972678	2014
Neonatal vitamin D status and risk of multiple sclerosis. Annals of neurology\| PubMed ID: 24985080	2014
Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general. Journal of neuroimmunology\| PubMed ID: 25037176	2014
A cell culture model for monitoring α-synuclein cell-to-cell transfer. Neurobiology of disease\| PubMed ID: 25046995	2015
No association between rheumatoid arthritis, amyotrophic lateral sclerosis, and tumour necrosis factor inhibitor treatment. Annals of the rheumatic diseases\| PubMed ID: 25096786	2014
Signaling networks in MS: a systems-based approach to developing new pharmacological therapies. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25112814	2015
Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort. European journal of human genetics : EJHG\| PubMed ID: 25159868	2015
Oral teriflunomide for patients with a first clinical episode suggestive of multiple sclerosis (TOPIC): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet. Neurology\| PubMed ID: 25192851	2014
Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis. Journal of proteome research\| PubMed ID: 25231264	2014
Obesity during childhood and adolescence increases susceptibility to multiple sclerosis after accounting for established genetic and environmental risk factors. Obesity research & clinical practice\| PubMed ID: 25263833	2014
Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells. Nature communications\| PubMed ID: 25278028	2014
Interaction between passive smoking and two HLA genes with regard to multiple sclerosis risk. International journal of epidemiology\| PubMed ID: 25324153	2014
Initial lymphocyte count and low BMI may affect fingolimod-induced lymphopenia. Neurology\| PubMed ID: 25361781	2014
β-Amyloid peptides and amyloid plaques in Alzheimer's disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 25371168	2015
Natalizumab exerts a suppressive effect on surrogates of B cell function in blood and CSF. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25392339	2015
Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25480867	2015
The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25505277	2015
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 25616667	2015
Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes. Brain : a journal of neurology\| PubMed ID: 25688078	2015
The Role of Environment and Lifestyle in Determining the Risk of Multiple Sclerosis. Current topics in behavioral neurosciences\| PubMed ID: 25707369	2015
Complement component C3 and butyrylcholinesterase activity are associated with neurodegeneration and clinical disability in multiple sclerosis. PloS one\| PubMed ID: 25835709	2015
γ-Secretase directly sheds the survival receptor BCMA from plasma cells. Nature communications\| PubMed ID: 26065893	2015
Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms. Brain, behavior, and immunity\| PubMed ID: 26189678	2016
Cell Fusion along the Anterior-Posterior Neuroaxis in Mice with Experimental Autoimmune Encephalomyelitis. PloS one\| PubMed ID: 26207625	2015
Fine mapping of bone structure and strength QTLs in heterogeneous stock rat. Bone\| PubMed ID: 26297441	2015
Class II HLA interactions modulate genetic risk for multiple sclerosis. Nature genetics\| PubMed ID: 26343388	2015
Effect of Smoking Cessation on Multiple Sclerosis Prognosis. JAMA neurology\| PubMed ID: 26348720	2015
PML: The Dark Side of Immunotherapy in Multiple Sclerosis. Trends in pharmacological sciences\| PubMed ID: 26497099	2015
MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated. Journal of neuroinflammation\| PubMed ID: 26511327	2015
Rat bone marrow-derived dendritic cells generated with GM-CSF/IL-4 or FLT3L exhibit distinct phenotypical and functional characteristics. Journal of leukocyte biology\| PubMed ID: 26516183	2016
A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases. Science translational medicine\| PubMed ID: 26560356	2015
The Expression of BAFF Is Controlled by IRF Transcription Factors. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26590315	2016
Translational utility of experimental autoimmune encephalomyelitis: recent developments. Journal of inflammation research\| PubMed ID: 26622189	2015
Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid. Journal of neuroinflammation\| PubMed ID: 26683050	2015
Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 26770997	2016
Posterior Accumulation of Tau and Concordant Hypometabolism in an Early-Onset Alzheimer's Disease Patient with Presenilin-1 Mutation. Journal of Alzheimer's disease : JAD\| PubMed ID: 26836192	2016
Pooled safety and tolerability data from four placebo-controlled teriflunomide studies and extensions. Multiple sclerosis and related disorders\| PubMed ID: 26856952	2016
[New techniques can radically change health care]. Lakartidningen\| PubMed ID: 26859854	2016
Anoctamin 2 identified as an autoimmune target in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26862169	2016
High-intensity resistance training in multiple sclerosis - An exploratory study of effects on immune markers in blood and cerebrospinal fluid, and on mood, fatigue, health-related quality of... Journal of the neurological sciences\| PubMed ID: 26944158	2016
Cerebrospinal fluid biomarkers of inflammation and degeneration as measures of fingolimod efficacy in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27003946	2016
Environmental factors and their interactions with risk genotypes in MS susceptibility. Current opinion in neurology\| PubMed ID: 27035899	2016
Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 27144214	2016
Multiple sclerosis and risk of young-adult-onset Hodgkin lymphoma. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 27144218	2016
Autoantibody targets in vaccine-associated narcolepsy. Autoimmunity\| PubMed ID: 27206786	2016
Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis. PloS one\| PubMed ID: 27224245	2016
Multiple sclerosis relapses are associated with increased fatigue and reduced health-related quality of life - A post hoc analysis of the TEMSO and TOWER studies. Multiple sclerosis and related disorders\| PubMed ID: 27237754	2016
Effect of high-dose vitamin D3 supplementation on antibody responses against Epstein-Barr virus in relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27325604	2016
Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27325759	2016
T-cell activation and HLA-regulated response to smoking in the deep airways of patients with multiple sclerosis. Clinical immunology (Orlando, Fla.)\| PubMed ID: 27339331	2016
Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 27386506	2016
TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells. Glia\| PubMed ID: 27479807	2016
Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies. Neurology. Genetics\| PubMed ID: 27540591	2016
Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis. Cell reports\| PubMed ID: 27626663	2016
Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk. Neurology. Genetics\| PubMed ID: 27652346	2016
IL-22 binding protein regulates murine skin inflammation. Experimental dermatology\| PubMed ID: 27676439	2016
Increased basal ganglia binding of (18) F-AV-1451 in patients with progressive supranuclear palsy. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 27709757	2016
Modeling strategies for quantification of in vivo 18F-AV1451 binding in patients with tau pathology. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 27765859	2016
Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing-remitting multiple sclerosis. Journal of neurochemistry\| PubMed ID: 27787906	2016