Roger Lecomte

Quantitative gated PET for the assessment of left ventricular function in small animals.

Assessment of cancer-associated biomarkers by positron emission tomography: advances and challenges.

Respiratory gating for 3-dimensional PET of the thorax: feasibility and initial results.

Breast cancer models to study the expression of estrogen receptors with small animal PET imaging.

Quantitative myocardial perfusion and coronary reserve in rats with 13N-ammonia and small animal PET: impact of anesthesia and pharmacologic stress agents.

Endotoxin-induced heart dysfunction in rats: assessment of myocardial perfusion and permeability and the role of fluid resuscitation.

Positron emission tomography imaging of tumor response after photodynamic therapy.

The effect of insulin on the intracellular distribution of 14(R,S)-[18F]Fluoro-6-thia-heptadecanoic acid in rats.

Dynamic imaging of transient metabolic processes by small-animal PET for the evaluation of photosensitizers in photodynamic therapy of cancer.

PET imaging of apoptosis with (64)Cu-labeled streptavidin following pretargeting of phosphatidylserine with biotinylated annexin-V.

A small animal positron emission tomography study of the effect of chemotherapy and hormonal therapy on the uptake of 2-deoxy-2-[F-18]fluoro-D-glucose in murine models of breast cancer.

A new tool for molecular imaging: the microvolumetric beta blood counter.

Standardization and detailed characterization of the syngeneic Fischer/F98 glioma model.

Comparison of analytical and algebraic 2D tomographic reconstruction approaches for irregularly sampled microCT data.

[11C] acetoacetate utilization by breast and prostate tumors: a PET and biodistribution study in mice.

Mechanism of reduced myocardial glucose utilization during acute hypertriglyceridemia in rats.

Novel detector technology for clinical PET.

PET study of 11C-acetoacetate kinetics in rat brain during dietary treatments affecting ketosis.

A pulse simulator for crystal identification validation of phoswich detectors used in positron emission tomography.

Abnormal in vivo myocardial energy substrate uptake in diet-induced type 2 diabetic cardiomyopathy in rats.

Cyclotron production of 99mTc: an approach to the medical isotope crisis.

Image-derived input function in dynamic human PET/CT: methodology and validation with 11C-acetate and 18F-fluorothioheptadecanoic acid in muscle and 18F-fluorodeoxyglucose in brain.

Mono- and tri-cationic porphyrin-monoclonal antibody conjugates: photodynamic activity and mechanism of action.

Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain.

Mild experimental ketosis increases brain uptake of 11C-acetoacetate and 18F-fluorodeoxyglucose: a dual-tracer PET imaging study in rats.

PET imaging using 64Cu-labeled sulfophthalocyanines: synthesis and biodistribution.

[18F]-fluoroestradiol quantitative PET imaging to differentiate ER+ and ERα-knockdown breast tumors in mice.

[11C]Acetate rest-stress protocol to assess myocardial perfusion and oxygen consumption reserve in a model of congestive heart failure in rats.

Predicting efficacy of photodynamic therapy by real-time FDG-PET in a mouse tumour model.

Comparative study of 64Cu/NOTA-[D-Tyr6,βAla11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging.

Positron emission tomography detection of human endothelial cell and fibroblast monolayers: effect of pretreament and cell density on 18FDG uptake.

Conversion of arterial input functions for dual pharmacokinetic modeling using Gd-DTPA/MRI and 18F-FDG/PET.

Small-animal PET: what is it, and why do we need it?

NEMA NU 4-2008 comparison of preclinical PET imaging systems.

Novel radiolabeled peptides for breast and prostate tumor PET imaging: (64)Cu/and (68)Ga/NOTA-PEG-[D-Tyr(6),βAla(11),Thi(13),Nle(14)]BBN(6-14).

EP 80317, a selective CD36 ligand, shows cardioprotective effects against post-ischaemic myocardial damage in mice.

Toward truly combined PET/CT imaging using PET detectors and photon counting CT with iterative reconstruction implementing physical detector response.

Blood compatible microfluidic system for pharmacokinetic studies in small animals.

The ketogenic diet increases brain glucose and ketone uptake in aged rats: a dual tracer PET and volumetric MRI study.

Quantitative hormone therapy follow-up in an ER+/ERαKD mouse tumor model using FDG and [11C]-methionine PET imaging.

PET-based geometrical calibration of a pinhole SPECT add-on for an animal PET scanner.

Mammary cancer bone metastasis follow-up using multimodal small-animal MR and PET imaging.

Assessment of the novel estrogen receptor PET tracer 4-fluoro-11β-methoxy-16α-[(18)F]fluoroestradiol (4FMFES) by PET imaging in a breast cancer murine model.

Angiotensin II-converting enzyme inhibition improves survival, ventricular remodeling, and myocardial energetics in experimental aortic regurgitation.

(68)Ga/DOTA- and (64)Cu/NOTA-phthalocyanine conjugates as fluorescent/PET bimodal imaging probes.

Fully 3D iterative CT reconstruction using polar coordinates.

Comment on "Temperature dependence of APD-based PET scanners" [Med. Phys. 40(9) 092506 (13pp.) (2013)].

Imaging performance of LabPET APD-based digital PET scanners for pre-clinical research.

Arterial input function sampling without surgery in rats for positron emission tomography molecular imaging.

Optimization of the reference region method for dual pharmacokinetic modeling using Gd-DTPA/MRI and (18) F-FDG/PET.

Deciphering PDT-induced inflammatory responses using real-time FDG-PET in a mouse tumour model.

[(11)C]-Acetoacetate PET imaging: a potential early marker for cardiac heart failure.

A Longitudinal Low Dose μCT Analysis of Bone Healing in Mice: A Pilot Study.

Endurance training or beta-blockade can partially block the energy metabolism remodeling taking place in experimental chronic left ventricle volume overload.

In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis.

[(18)F]-fluorodeoxyglucose positron emission tomography of the cat brain: A feasibility study to investigate osteoarthritis-associated pain.

A real-time follow-up of photodynamic therapy during PET imaging.

Radioisotopic Purity of Sodium Pertechnetate 99mTc Produced with a Medium-Energy Cyclotron: Implications for Internal Radiation Dose, Image Quality, and Release Specifications.

Multipinhole SPECT helical scan parameters and imaging volume.

Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism.

Metabolic activity of brown, "beige," and white adipose tissues in response to chronic adrenergic stimulation in male mice.

Postprandial fatty acid uptake and adipocyte remodeling in angiotensin type 2 receptor-deficient mice fed a high-fat/high-fructose diet.

Real-Time Microfluidic Blood-Counting System for PET and SPECT Preclinical Pharmacokinetic Studies.

Clinical Trial with Sodium (99m)Tc-Pertechnetate Produced by a Medium-Energy Cyclotron: Biodistribution and Safety Assessment in Patients with Abnormal Thyroid Function.

mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.

Simulation of scintillation light output in LYSO scintillators through a full factorial design.

A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate.

Impact of dianionic and dicationic linkers on tumor uptake and biodistribution of [(64) Cu]Cu/NOTA peptide-based gastrin-releasing peptide receptors antagonists.

Loss of UCP2 impairs cold-induced non-shivering thermogenesis by promoting a shift toward glucose utilization in brown adipose tissue.

Toward truly combined PET/CT imaging using PET detectors and photon counting CT with iterative reconstruction implementing physical detector response.

Improved Estrogen Receptor Assessment by PET Using the Novel RadiotracerF-4FMFES in Estrogen Receptor-Positive Breast Cancer Patients: An Ongoing Phase II Clinical Trial.

The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis.

Targeting IL-5Rα with antibody-conjugates reveals a strategy for imaging and therapy for invasive bladder cancer.