サインイン

The Medicines and Healthcare Products Regulatory Agency (MHRA)

1 ARTICLES PUBLISHED IN JoVE

image

Immunology and Infection

Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety
Elliot MacLeod 1, Deepa Rajagopal 1, Sandrine Vessillier 1
1The Medicines and Healthcare Products Regulatory Agency (MHRA)

The use of cytokine release assay reference reagents allows for more reproducible and standardized in vitro safety profiles of immunotherapeutic monoclonal antibodies. Here we describe how cytokine release assays can be used alongside a reference reagent panel to predict the safety of some therapeutic monoclonal antibodies.

JoVE Logo

個人情報保護方針

利用規約

一般データ保護規則

研究

教育

JoVEについて

Copyright © 2023 MyJoVE Corporation. All rights reserved