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3 ARTICLES PUBLISHED IN JoVE

Medicine

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

Mark Nowell¹, Roman Rodionov¹, Gergely Zombori², Rachel Sparks², Michele Rizzi¹, Sebastien Ourselin², Anna Miserocchi³, Andrew McEvoy³, John Duncan¹

¹Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, ²Center of Medical Imaging and Computing, UCL, ³Department of Neurosurgery, National Hospital for Neurology and Neurosurgery

We describe the steps to use our custom designed software for image integration, visualization and planning in epilepsy surgery.

Engineering

Three-Dimensional Ultrasonic Needle Tip Tracking with a Fiber-Optic Ultrasound Receiver

Wenfeng Xia^1,2, Simeon J. West³, Malcolm C. Finlay^2,4, Rosalind Pratt^5,6, Sunish Mathews^1,2, Jean-Martial Mari⁷, Sebastien Ourselin^1,2,6, Anna L. David^1,5,8,9, Adrien E. Desjardins^1,2

¹Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, ²Department of Medical Physics and Biomedical Engineering, University College London, ³Department of Anaesthesia, University College Hospital, ⁴St Bartholomew's Hospital and Queen Mary University of London, ⁵Institute for Women's Health, University College London, ⁶Centre for Medical Imaging Computing, University College London, ⁷GePaSud, University of French Polynesia, ⁸Department of Development and Regeneration, KU Leuven (Katholieke Universiteit), ⁹NIHR University College London Hospitals Biomedical Research Centre

Accurate and efficient visualization of invasive medical devices is extremely important in many ultrasound-guided minimally invasive procedures. Here, a method for localizing the spatial position of a needle tip relative to the ultrasound imaging probe is presented.

Bioengineering

Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning

Eleanor C. Mackle^*1,2, Jonathan Shapey^*1,2,3,4, Efthymios Maneas^1,2, Shakeel R. Saeed^3,5,6, Robert Bradford³, Sebastien Ourselin⁴, Tom Vercauteren⁴, Adrien E. Desjardins^1,2

¹Wellcome / EPSRC Centre for Interventional and Surgical Sciences, University College London, ²Department of Medical Physics and Biomedical Engineering, University College London, ³Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, ⁴School of Biomedical Engineering & Imaging Sciences, King's College London, ⁵The Ear Institute, University College London, ⁶The Royal National Throat, Nose and Ear Hospital, London

This protocol describes the fabrication of a patient specific skull, brain and tumor phantom. It uses 3D printing to create molds, and polyvinyl alcohol (PVA-c) is used as the tissue mimicking material.