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UCL

3 ARTICLES PUBLISHED IN JoVE

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Medicine

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery
Mark Nowell 1, Roman Rodionov 1, Gergely Zombori 2, Rachel Sparks 2, Michele Rizzi 1, Sebastien Ourselin 2, Anna Miserocchi 3, Andrew McEvoy 3, John Duncan 1
1Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, 2Center of Medical Imaging and Computing, UCL, 3Department of Neurosurgery, National Hospital for Neurology and Neurosurgery

We describe the steps to use our custom designed software for image integration, visualization and planning in epilepsy surgery.

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Engineering

Three-Dimensional Ultrasonic Needle Tip Tracking with a Fiber-Optic Ultrasound Receiver
Wenfeng Xia 1,2, Simeon J. West 3, Malcolm C. Finlay 2,4, Rosalind Pratt 5,6, Sunish Mathews 1,2, Jean-Martial Mari 7, Sebastien Ourselin 1,2,6, Anna L. David 1,5,8,9, Adrien E. Desjardins 1,2
1Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, 2Department of Medical Physics and Biomedical Engineering, University College London, 3Department of Anaesthesia, University College Hospital, 4St Bartholomew's Hospital and Queen Mary University of London, 5Institute for Women's Health, University College London, 6Centre for Medical Imaging Computing, University College London, 7GePaSud, University of French Polynesia, 8Department of Development and Regeneration, KU Leuven (Katholieke Universiteit), 9NIHR University College London Hospitals Biomedical Research Centre

Accurate and efficient visualization of invasive medical devices is extremely important in many ultrasound-guided minimally invasive procedures. Here, a method for localizing the spatial position of a needle tip relative to the ultrasound imaging probe is presented.

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Bioengineering

Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning
Eleanor C. Mackle *1,2, Jonathan Shapey *1,2,3,4, Efthymios Maneas 1,2, Shakeel R. Saeed 3,5,6, Robert Bradford 3, Sebastien Ourselin 4, Tom Vercauteren 4, Adrien E. Desjardins 1,2
1Wellcome / EPSRC Centre for Interventional and Surgical Sciences, University College London, 2Department of Medical Physics and Biomedical Engineering, University College London, 3Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, 4School of Biomedical Engineering & Imaging Sciences, King's College London, 5The Ear Institute, University College London, 6The Royal National Throat, Nose and Ear Hospital, London

This protocol describes the fabrication of a patient specific skull, brain and tumor phantom. It uses 3D printing to create molds, and polyvinyl alcohol (PVA-c) is used as the tissue mimicking material.

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