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Universidad de Antioquia

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Federico Perdomo-Celis^1,2, Sandra Medina-Moreno¹, Alonso Heredia¹, Harry Davis¹, Joseph Bryant¹, Juan Carlos Zapata¹

¹Institute of Human Virology, School of Medicine, University of Maryland, ²Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia

Described here are three experimental approaches for studying the dynamics of HIV infection in humanized mice. The first permits the study of chronic infection events, whereas the two latter allows for the study of acute events after primary infection or viral reactivation.