An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human OmentumTerrence Wong 1, Roslyn Tedja 2, Hussein Chehade 2, Robert Morris 1, Ayesha B. Alvero 2, Gil Mor 2
1Department of Gynecologic Oncology, Karmanos Cancer Institute, 2C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University School of Medicine
This protocol describes the establishment of a three-dimensional (3D) ex vivo model of cancer cell-omentum interaction. The model provides a platform for elucidating pro-tumor mechanisms within the adipose niche and for testing novel therapies.
